Results 151 to 160 of about 23,719,178 (251)

Universal, Rapid, and Cleavable Labeling of Antibodies by Fluorophores and DNA Oligonucleotides for Multiplex Immunostaining and Spatial Proteomics Through MIST Linker. [PDF]

Biosensors (Basel)
Meah A, Yin S, Anderson SS, Lin M, Liang S, Davuluri M, Qin YX, Mallipattu SK, Wang J.   +8 more
europepmc   +1 more source

Plant cis‐regulatory grammar: Decoding the multidimensional code of transcriptional regulation for programmable crop engineering

Journal of Integrative Plant Biology, EarlyView.
This review decodes the grammar of plant cis‐regulatory elements, revealing that their function emerges from sequence, chromatin accessibility, 3D topology, and cell type context. It highlights how single‐cell omics, CRISPR dissection, and AI‐driven design converge to enable predictive engineering and crop improvement. ABSTRACT Cis‐regulatory elements (
Libin Zhang, Maoteng Li
wiley   +1 more source

Safety and toxicity assessment of antisense oligonucleotides in brain-relevant human cellular models. [PDF]

Mol Ther Nucleic Acids
Colar Zanjko L, Andrés-Santamaria R, Balogh A, van Roon-Mom WMC, Dinnyés A.   +4 more
europepmc   +1 more source

Characterisation of human hair follicle development

Journal of Anatomy, EarlyView.
Schematic of hair follicle development in human skin. Hair follicle primordia of similar sizes, but different densities, are laid out across the skin. The distinction between terminal and vellus hair sites is not obvious at early stages of hair follicle development.
Zoe R. Sudderick, James D. Glover, Cameron Batho‐Samblas, Barbara Bo‐Ju Shih, Denis J. Headon   +4 more
wiley   +1 more source

Molecular Diagnostics of Infectious Diseases. [PDF]

Yonago Acta Med
Takata M, Chikumi H, Yoshifuji A.
europepmc   +1 more source

Archaeal Cytoskeletal Protein CetZ1 Influences Assembly of the Motility Machinery

Molecular Microbiology, EarlyView.
The Haloferax volcanii tubulin‐like protein CetZ1 is required for rod‐cell morphogenesis and motility. We show that CetZ1 loss or GTPase inactivation impairs assembly of the motility machinery, including the archaellum base protein ArlD, the chemotaxis adaptor CheW1, and the response regulator CheY.
Hannah J. Brown, Md Imtiazul Islam, Juanfang Ruan, Matthew A. B. Baker, Solenne Ithurbide, Iain G. Duggin   +5 more
wiley   +1 more source

Toward Comprehensive Clinical Genomics: Integrating Exon-Level Analysis for Detecting Monogenic Copy Number Variations. [PDF]

Ann Lab Med
Seo EJ.
europepmc   +1 more source

High‐variance phenome database reveals important roles of WD40 proteins in the plant pathogenic fungus Fusarium graminearum

New Phytologist, EarlyView.
Functional analysis of predicted interaction‐associated WD40 blades in Fgwd101 and Fgwd048 of Fusarium graminearum. Summary WD40 is a highly conserved protein domain in eukaryotes that functions as a versatile platform for protein–protein interactions and participates in diverse biological processes.
Soyoung Choi, Nahyun Lee, Jiyeun Park, Hosung Jeon, Sieun Kim, Jung‐Eun Kim, Jiyoung Shin, Heeji Moon, Kyunghun Min, Yejin Choi, Aram Hwangbo, Hun Kim, Gyung Ja Choi, Yin‐Won Lee, Dae‐Geun Song, Hokyoung Son   +15 more
wiley   +1 more source

Toward Multi(radio)metalated DNA: Enzymatic Polymerization of Metal-Chelate-Modified Deoxyribonucleoside Triphosphates. [PDF]

Angew Chem Int Ed Engl
Wong AAWL, Bénard F, Perrin DM.
europepmc   +1 more source

Machine Learning-Enhanced Ultrasensitive Immuno-CRISPR Array Facilitates Early Diagnosis of Alzheimer's Disease by Detecting Multiple Plasma Biomarkers. [PDF]

Adv Sci (Weinh)
This work presents a CRISPR‐based, ultrasensitive multiplex protein detection array capable of simultaneously analyzing six plasma biomarkers associated with Alzheimer's disease (AD). By integrating antibody‐mediated signal transduction, recombinase polymerase amplification, and spatially encoded CRISPR‐Cas12a, the system achieves detection sensitivity
Zhang L, Yang C, Yao Q, Du X, Ding S, Shi Y, Sheng C, Wang M, Han Y, Luo H.   +9 more
europepmc   +2 more sources