Results 181 to 190 of about 130,578 (251)

Development of Enhanced Separation Techniques for Oligonucleotides Utilizing Mixed-Mode Chromatography and 2D-LC/UV/MS Analysis. [PDF]

J Sep Sci
Haglöf J, Nilsson JM, Ludvigsson JW.
europepmc   +1 more source

Novel Bioconjugate Materials: Synthesis, Characterization and Medical Applications

Advanced Healthcare Materials, Volume 14, Issue 31, December 8, 2025.
This review discusses the bioconjugation of novel materials grouped under “biological”, “hybrid” and “synthetic” categories. Medical applications ranging from cancer therapy and diagnostics to optogenetics and tissue engineering are explored, and conjugation trends are highlighted as a general guide. The review concludes with a comparison of techniques
Ellie Martin, Sean P. Doidge, Eiman Aleem, Suela Kellici, Steven Dunn, Claire Atkinson, Philip D. Howes   +6 more
wiley   +1 more source

Mapping of HOCl-oxidized RNA identifies abasic sites as major damage and oxidation product of oxo⁸G. [PDF]

Nat Commun
Weber M, Raorane K, Grampp CJ, Bourguignon V, Kilz LM, Glänzer D, Marchand V, Kreutz C, Motorin Y, Helm M.   +9 more
europepmc   +1 more source

DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications

Advanced Materials, Volume 37, Issue 49, December 10, 2025.
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding, Bing Liu, Andreas Peil, Sisi Fan, Jie Chao, Na Liu   +5 more
wiley   +1 more source

Compact RNA sensors for increasingly complex functions of multiple inputs. [PDF]

Nat Chem
Choe CA, Andreasson JOL, Melaine F, Kladwang W, Wu MJ, Portela F, Wellington-Oguri R, Nicol JJ, Wayment-Steele HK, Gotrik M, Eterna Participants, Khatri P, Greenleaf WJ, Das R.   +13 more
europepmc   +1 more source

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

Advanced Materials, Volume 37, Issue 48, December 3, 2025.
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi, Yadi Fan, Qin Zhang, Yingying Huang, Mo Yang   +4 more
wiley   +1 more source

Repurposing large-format microarrays for scalable spatial transcriptomics. [PDF]

Nat Methods
Cipurko D, Ueda T, Mei L, Chevrier N.
europepmc   +1 more source

PRDM16 Reduces Cellular Senescence by Upregulating GSTM1

Advanced Science, Volume 12, Issue 45, December 4, 2025.
Cellular senescence drives aging and aging‐related organ disorders, yet PRDM16's role remains unexplored. This work uncovers that PRDM16 decreases significantly in aged organs, while its loss accelerates cellular senescence and aging‐related organ injury.
Qian Yuan, Yuting Zhu, Ben Tang, Yaru Xie, Mingcun Hu, Hua Su, Youhua Liu, Chun Zhang   +7 more
wiley   +1 more source

Anticodon Engineered Transfer RNA (tRNASUAG) Inhibits Hepatitis B Virus Replication by Promoting the Degradation of Core Protein

Advanced Science, Volume 12, Issue 45, December 4, 2025.
This study employed tRNASUAG, an anticodon‐engineered tRNA (ACE‐tRNA), to introduce a phosphorylatable serine into the C‐terminal domain of HBc by reading through its stop codon, thereby potentially promoting the ubiquitin‐proteasome degradation of HBc, and subsequently inhibiting HBV replication. Through a tRNASUAG‐gHBV1‐tRNASUAG‐gHBV2‐tRNASUAG tandem
Xingwen Yang, Huiying Sun, Ziheng Luo, Qinxin Zhang, Yarong Song, Jie Li, Xiaoyun Liu, Jie Wang   +7 more
wiley   +1 more source

Genome-wide association study of agronomic traits in winter wheat (Triticum aestivum L.) using a custom SNP marker set. [PDF]

BMC Plant Biol
Bazhenov M, Bespalova L, Samarina M, Polevikova N, Agaeva E, Debeliy A, Beliakova A, Ponisko A, Nazarova L, Chernook A, Karlov G, Divashuk M.   +11 more
europepmc   +1 more source