Results 181 to 190 of about 131,505 (250)

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, Volume 36, Issue 1, 2 January 2026.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Specificity of the stabilizing interaction between intrinsically disordered protein sequences and G-quadruplexes in RNA. [PDF]

Nucleic Acids Res
Cox LB, Mattick JS, Middleton IA, Rizzuto FJ, Thordarson P.   +4 more
europepmc   +1 more source

Biogenic Next‐Gen CPL Emitters: Strategies with Proteins, Polysaccharides, and Nucleotides

Advanced Optical Materials, Volume 14, Issue 1, 9 January 2026.
Biogenic molecules such as proteins, peptides, saccharides, and DNA can act as natural scaffolds for generating circularly polarized luminescence (CPL). This review highlights recent strategies exploiting these inherently chiral frameworks to achieve light emission with controllable handedness under unpolarized excitation, bridging biological ...
Ricardo Chavez‐Jimenez, Gustavo González‐Gaitano, Julio Fernandez‐Cestau, Mattia Nieddu, Juan Pablo Fuenzalida‐Werner   +4 more
wiley   +1 more source

Quantifying transcription factor specificity with advanced DNA universal microarrays featuring long and modified binding sites. [PDF]

Nucleic Acids Res
Bayer Y, O'Hagan MP, Miodownik I, Afek A.   +3 more
europepmc   +1 more source

Cryptocyanine‐Based Fluorescent Probes for DNA Detection: Controlling Solubility and Aggregation Through Side Chain Design

Advanced Sensor Research, Volume 5, Issue 1, January 2026.
Cryptocyanine‐based fluorogenic DNA probes with improved water solubility and reduced aggregation were developed by tuning side‐chain polarity. The derivatives exhibit high fluorescence enhancement upon DNA binding, highlighting their potential as environment‐sensitive tools for nucleic acid detection and bioanalytical applications.
Farkas Domahidy, Levente Cseri, Gábor Turczel, Blanka Huszár, Balázs J. Rózsa, Zoltán Mucsi, Ervin Kovács   +6 more
wiley   +1 more source

Comprehensive web-based platform for advanced PCR design, genotyping, synthetic biology, molecular diagnostics, and sequence analysis. [PDF]

Mol Ther Nucleic Acids
Kalendar R.
europepmc   +1 more source

Single Cell and Spatial Transcriptomics Define a Proinflammatory and Profibrotic Niche After Kidney Injury

Advanced Science, Volume 13, Issue 2, 9 January 2026.
By integrating single‐cell RNA sequencing and spatial transcriptomics, tenascin C (TNC) is unveiled as a central organizer of the proinflammatory and profibrotic niche in kidney fibrosis. TNC promotes macrophage activation through TLR4/NF‐κB signaling, leading to renal inflammation and fibrosis.
Li Li, Jinlin Liao, Yuxi Zhang, Zifu Yao, Junxin Huang, Kejia Wu, Lu Li, Yiling Peng, Haili Zhu, Xue Hong, Xi Liu, Lili Zhou, Fan Fan Hou, Haiyan Fu, Youhua Liu   +14 more
wiley   +1 more source

A 4NsL chromosome segment from <i>Leymus mollis</i> confers stripe rust and Fusarium head blight resistance in wheat. [PDF]

Front Plant Sci
Du X, Jin Y, Ren W, Ge D, Xu X, Zhao X, Wang Y, Li T, Zhao J, Wang C, Li T, Chen C, Liu X, Deng P, Ji W.   +14 more
europepmc   +1 more source

First description of co-occurrence of 49,XXXXY and X-linked Cornelia de Lange syndrome: case report. [PDF]

Front Endocrinol (Lausanne)
Al-Rashdi S, Ekstrom L, Collins A, Schulz HL, Dinwiddie A, Samango-Sprouse C, Olaya M, Moser E, Green AJ.   +8 more
europepmc   +1 more source

Red Blood Cell‐Derived Exosomal miR‐93‐5p Promotes Lung Cancer Progression through PTEN Suppression

Advanced Science, Volume 13, Issue 3, 14 January 2026.
Red blood cell (RBC)‐derived exosomal miR‐93‐5p is elevated in lung cancer patients and correlates with poor outcomes. Exosomal miR‐93‐5p suppresses PTEN in cancer cells, enhancing proliferation, migration, and invasion. In mouse models, therapeutic inhibition with ASO‐miR‐93 5p reduces tumor growth, highlighting a bidirectional tumor‐RBC‐tumor axis ...
Ning Li, Pushpa Dhilipkannah, Van K Holden, Ashutosh Sachdeva, Feng Jiang   +4 more
wiley   +1 more source