Results 221 to 230 of about 708,274 (274)

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2021–2022

Mass Spectrometry Reviews, Volume 44, Issue 3, Page 213-453, May/June 2025.
Abstract The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022.
David J. Harvey
wiley   +1 more source

Hyphenation of microflow chromatography with electrospray ionization mass spectrometry for bioanalytical applications focusing on low molecular weight compounds: A tutorial review

Mass Spectrometry Reviews, Volume 44, Issue 3, Page 491-512, May/June 2025.
Abstract Benefits of miniaturized chromatography with various detection modes, such as increased sensitivity, chromatographic efficiency, and speed, were recognized nearly 50 years ago. Over the past two decades, this approach has experienced rapid growth, driven by the emergence of mass spectrometry applications serving ‐omics sciences and the need ...
Sergey Girel, Isabel Meister, Gaetan Glauser, Serge Rudaz   +3 more
wiley   +1 more source

Dsembler - DNA Assembly Designer: A Tool for Facilitating Assembly of Oligomers. [PDF]

J Microbiol Biotechnol
Gupta A, Park G, Park SY, Kim H, Rha E, Lee DH, Lee SG, Kim H.   +7 more
europepmc   +1 more source

α‐Synuclein in Parkinson's Disease: From Bench to Bedside

Medicinal Research Reviews, Volume 45, Issue 3, Page 909-946, May 2025.
ABSTRACT α‐Synuclein (α‐syn), a pathological hallmark of PD, is emerging as a bridging element at the crossroads between neuro/immune‐inflammatory responses and neurodegeneration in PD. Several evidence show that pathological α‐syn accumulates in neuronal and non‐neuronal cells (i.e., neurons, microglia, macrophages, skin cells, and intestinal cells ...
Gabriele Bellini, Vanessa D'Antongiovanni, Giovanni Palermo, Luca Antonioli, Matteo Fornai, Roberto Ceravolo, Nunzia Bernardini, Pascal Derkinderen, Carolina Pellegrini   +8 more
wiley   +1 more source

Genomic structural variants analysis in leukemia by a novel cytogenetic technique: Optical genome mapping. [PDF]

Cancer Sci
Lu S, Liu K, Wang D, Ye Y, Jiang Z, Gao Y.   +5 more
europepmc   +1 more source

The value of age of onset and family history as predictors of molecular diagnosis in a Swedish cohort of inherited retinal disease

Acta Ophthalmologica, Volume 103, Issue 3, Page 327-338, May 2025.
Abstract Purpose This study aimed to characterize clinical and genetic findings in a Swedish cohort with inherited retinal disease (IRD), identify predictors for achieving a molecular diagnosis and evaluate the effects of increased genetic testing over time.
Karl De Geer, Stefan Löfgren, Anna Lindstrand, Malin Kvarnung, Erik Björck   +4 more
wiley   +1 more source

Editorial Note: Design and characterization of an 87k SNP genotyping array for Arctic charr (Salvelinus alpinus). [PDF]

PLoS One
PLOS ONE Editors.
europepmc   +1 more source

Hybrid DNA Origami – Graphene Platform for Electrically‐Gated Nanoscale Motion

Advanced Materials Interfaces, Volume 12, Issue 8, April 21, 2025.
A hybrid DNA origami‐graphene architecture is employed in a nearfield sensing device for optical distance assessment in biosensors and biorecognition purposes. Using Fluorescence Lifetime Imaging Microscopy (FLIM), a nearfield quenching model is verified and test the device response under several electrostatic gating conditions, which leads to changes ...
João D. G. Azevedo, Tiago Queirós, Filipe Camarneiro, Maria João Lopes, João Freitas, Agnes Purwidyantri, Praneetha Sundar Prakash, Soumya Chandrasekhar, Thorsten‐Lars Schmidt, Pedro Alpuim, Jana B. Nieder   +10 more
wiley   +1 more source

In silico PCR analysis: a comprehensive bioinformatics tool for enhancing nucleic acid amplification assays. [PDF]

Front Bioinform
Kalendar R, Shevtsov A, Otarbay Z, Ismailova A.   +3 more
europepmc   +1 more source

Electrochemical Detection of BRAF V600E Mutation in a Liquid Biopsy Format: LAMPing the Way to an Improved Diagnostics and Treatment

Advanced Materials Technologies, Volume 10, Issue 7, April 4, 2025.
Simple and rapid technology is developed for the analysis of BRAF V600E point mutation. It combines isothermal LAMP reaction to selectively amplify only mutated DNA, with electrochemical readout at screen‐printed electrode chips. The bioplatform is successfully applied to tumor tissue DNA and circulating tumor DNA in serum from colorectal carcinoma and
Ludmila Moranova, Johana Strmiskova, Katerina Ondraskova, Miroslav Bardelcik, Matous Cwik, Igor Kiss, Roman Hrstka, Martin Bartosik   +7 more
wiley   +1 more source