Results 261 to 270 of about 1,424,575 (357)

Quantitative determination of intracellular miRNA content using dual gold and iron nanoreporters and single particle ICP-ToF-MS. [PDF]

Mikrochim Acta
González Morales S, Añón Álvarez E, Clases D, Corte-Rodriguez M, Montes-Bayón M.   +4 more
europepmc   +1 more source

The Long Noncoding RNA ΒFaar Promotes White Adipose Tissue Browning and Prevents Diet‐Induced Obesity

Advanced Science, EarlyView.
βFaar selectively targets and inhibits the GTPase activity of the RAB18 protein, thereby reducing LD volume. Conversely, βFaar promotes nuclear translocation of the transcription factor IRF4 in inguinal white adipose tissue (iWAT), facilitating the browning of white adipose tissue and attenuating body fat accumulation.
Yue Yang, Bin Huang, Baixue Sha, Danni Gao, Yimeng Qin, Ziyi Li, Xi Chen, Yinuo Jin, Yi Pan, Yanfeng Zhang, Yumeng Shen, Yu Liu, Liang Jin, Fangfang Zhang   +13 more
wiley   +1 more source

DNA-Based Nanobiosensor for the Colorimetric Detection of Dengue Virus Serotype 2 Synthetic Target Oligonucleotide. [PDF]

Biosensors (Basel)
Flores MSC, Alocilja EC, Amalin DM, Aguila MJB, Purificacion MV, Merca FE, Manuel MCC, Dimamay MPS, Bautista MAM, Fernando LM.   +9 more
europepmc   +1 more source

Phylogenetic Analysis of and Oligonucleotide Probe Development for Eikelboom Type 021N Filamentous Bacteria Isolated from Bulking Activated Sludge

, 2000
Takahiro Kanagawa, Yoichi Kamagata, Shinobu Aruga, Tetsuro Kohno, Matthias Horn, Michael Wagner   +5 more
openalex   +1 more source

Gene Editing of a Susceptibility LncRNA Enhances Broad‐Spectrum Disease Resistance in Rice without Developmental Trade‐Offs

Advanced Science, EarlyView.
Editing susceptibility lncRNAs offers a strategy to enhance disease resistance without yield loss. RESIS, a domestication‐acquired, pathogen‐induced lncRNA, promotes protein N‐terminal acetylation through its interaction with NatA complex. Knockout of RESIS increases translation and confers broad‐spectrum resistance to both fungal and bacterial ...
Wen‐long Zhao, Ye Cheng, Jia‐hui Huang, Jun‐jie Feng, Hui‐yin Pang, Yi‐chao Qin, Zheng‐tong Chen, Yu Cheng, Jian‐ping Lian, Yan‐fei Zhou, Rui‐rui He, Meng‐qi Lei, Zi‐qin Cao, Lu Yang, Chao Yuan, Jie Jiang, Yue‐qin Chen, Yu‐chan Zhang   +17 more
wiley   +1 more source

Highly Ordered DNA Framework Interface Enables Efficient Enzymatic Oligonucleotide Synthesis

Advanced Science, EarlyView.
Tetrahedral DNA nanostructures (TDN) ‐based nanoscopic interface provides ordered upright orientation and optimal spacing for initiator primers, enhancing enzyme accessibility in interfacial enzymatic oligonucleotide synthesis (EOS). Notably, efficient TDN‐based EOS is employed for DNA information storage by synthesizing a 60‐nucletide DNA fragment ...
Kunjie Li, Dongbao Tang, Xiaoyun Lu, Xinyao Yang, Luxuan Liu, Zhaoyuan Jia, Zhi Zhu, Yuyu Tan, Huimin Zhang, Chaoyong Yang   +9 more
wiley   +1 more source

A Software Tool for Reagent Design to Expand Access to Single-Nucleotide Variant Detection by the Oligonucleotide Ligation Assay. [PDF]

J Mol Diagn
Nelson DJ, Chugh K, Pua HH, Haselton FR.
europepmc   +1 more source

Quorum Sensing Inhibits Type III‐A CRISPR‐Cas System Activity Through Repressing Positive Regulators SarA and ArcR in Staphylococcus Aureus

Advanced Science, EarlyView.
This study proposes a novel model illustrating how quorum sensing (QS) regulates the type III‐A CRISPR‐Cas system in Staphylococcus aureus. The QS regulator AgrA suppresses CRISPR‐Cas activity by downregulating the transcriptional regulators SarA and ArcR.
Yang Li, Yuanyue Tang, Xiaofei Li, Nina Molin Høyland‐Kroghsbo, Hanne Ingmer, Xinan Jiao, Qiuchun Li   +6 more
wiley   +1 more source

Approaches for Identifying LncRNA-Associated Proteins for Therapeutic Targets and Cancer Biomarker Discovery. [PDF]

Targets (Basel)
Hussain MS, Vij P, Kotnala S, Ahmad S, Chauhan SC, Tripathi MK.   +5 more
europepmc   +1 more source

A Natural Major Module Confers the Trade‐Off between Phenotypic Mean and Plasticity of Grain Chalkiness in Rice

Advanced Science, EarlyView.
This study reveals the genetic and molecular mechanisms controlling the general trade‐off between phenotypic mean and plasticity of grain chalkiness in rice and identifies two major external drivers (high temperature and wide grain) and a natural major module (GCP6‐MPC5) that control this trade‐off.
Juncheng Zhang, Yu Du, Pengkun Xu, Luyu Zhong, Zhi Li, Wenran Zhu, Yicheng Li, Bo Cheng, Xinyuan Chang, Yawei Fan, Yibo Li   +10 more
wiley   +1 more source