Results 171 to 180 of about 119,501 (270)

RNA-based therapies for neurodevelopmental disorders: innovative tools for molecular correction. [PDF]

Front Mol Biosci
Drongitis D, Verrillo L, de Bellis A, Miano MG.   +3 more
europepmc   +1 more source

Strigolactones Regulate Sugar Allocation to Control Rice Tillering and Root Development via the OsSPL14‐OsSHR1‐OsSWEET16 Pathway

Plant Biotechnology Journal, EarlyView.
ABSTRACT Strigolactones (SLs) are root‐to‐shoot phytohormones that regulate tillering (branching) and root development. Sugar, as an essential energy substance and signalling molecule, plays a fundamental role in the growth and development of plants. However, the molecular mechanisms by which SL directly regulates sugar allocation to control tillering ...
Miao Feng, Wenfan Luo, Sheng Luo, Rong Miao, Manpo Gu, Shuai Li, Xinxin Xing, Jinhui Zhang, Jinsheng Qian, Xin Liu, Chunlei Zhou, Qi Sun, Tong Luo, Nuo Chen, Yulong Ren, Zhijun Cheng, Cailin Lei, Zhichao Zhao, Shanshan Zhu, Xin Wang, Xiuping Guo, Qibing Lin, Jianmin Wan   +22 more
wiley   +1 more source

Enhancing the intracellular delivery of antisense oligonucleotides (ASO) : a comparative study of aptamer, vitamin E, and cholesterol ASO conjugates. [PDF]

RSC Adv
Balachandran AA, Poudel BH, Rahimizadeh K, Chikkanna A, Veedu RN.   +4 more
europepmc   +1 more source

ZmMYB127 Modulates Maize Kernel Texture and Size by Integrating the Synthesis of Starch, Zein Proteins and Auxin

Plant Biotechnology Journal, EarlyView.
ABSTRACT Kernel texture is an important agronomic trait that determines the end‐uses of maize kernels and affects their integrity at harvest and susceptibility to pests and diseases. The ratio of the vitreous endosperm (RVE) is the key index for assessing kernel texture, and identifying key genes involved in its formation is crucial for maize breeding.
Tiandan Long, Yayun Wang, Zhou Liu, Yongbin Wang, Changqing Mao, Dening Wang, Aying Qin, Qiang Liao, Jin Yang, Xiujun Fan, Lei Gao, Yufeng Hu, Jing Wang, Yubi Huang, Yangping Li   +14 more
wiley   +1 more source

Viral and non-viral cellular therapies for neurodegeneration. [PDF]

Front Med (Lausanne)
Srivastav J, Sharma S.
europepmc   +1 more source

Protein production is an early biomarker for RNA‐targeted therapies [PDF]

, 2018
Alex, Jacob, Barthélemy, Nicolas, Bateman, Randall J, Bollinger, James G, Cole, Tracy, Kordasiewicz, Holly B, Miller, Timothy M, Sato, Chihiro, Schoch, Kathleen M, Self, Wade K, Swayze, Eric   +10 more
core   +2 more sources

CsYABBY1 and CsMYB114 Enhance Acquired Drought Tolerance by Mediating Flavonoid Biosynthesis in Camellia sinensis

Plant Biotechnology Journal, EarlyView.
ABSTRACT Drought priming is a critical agronomic strategy for enhancing plant drought tolerance, yet the optimal priming intensity and transcriptional regulatory mechanisms underlying subsequent drought responses in the tea plant (Camellia sinensis) remain poorly characterised.
Caiyun Tian, Chengzhe Zhou, Shengjing Wen, Cheng Zhang, Anru Zheng, Lele Jiang, Niannian Yang, Zhuo Tang, Xiaowen Hu, Zhendong Zhang, Jiaxin Fang, Zhong Wang, Yuqiong Guo   +12 more
wiley   +1 more source

Discovery of long-acting APOC3 siRNA for treating patients with hypertriglyceridemia. [PDF]

Nucleic Acids Res
Prakash TP, Mullick AE, Riney S, Yu J, Nikan M, Quirk C, Crutchfield A, Damle SS, Klein S, Swayze EE.   +9 more
europepmc   +1 more source

Precision RNAi in Tomato Using Synthetic Trans‐Acting Small Interfering RNAs Derived From Minimal Precursors

Plant Biotechnology Journal, EarlyView.
ABSTRACT RNA interference (RNAi) is a highly conserved gene silencing mechanism regulating gene expression at transcriptional and post‐transcriptional levels in plants. Synthetic trans‐acting small interfering RNAs (syn‐tasiRNAs) have emerged as powerful tools for highly specific and efficient gene silencing.
Ariel H. Tomassi, María Juárez‐Molina, Adriana E. Cisneros, Ana Alarcia, Francesca Orlando, Sara Toledano‐Franco, Silvia Presa, Antonio Granell, Alberto Carbonell   +8 more
wiley   +1 more source

Gene expression silencing therapy in tumors, focus on gastrointestinal and genitourinary tumors. [PDF]

Front Immunol
El-Ghazzi N, Italiano A, Angeli E.
europepmc   +1 more source