Results 91 to 100 of about 414,656 (346)
Applications of Biomolecular Nanostructures for Anti-Angiogenic Theranostics
International Journal of NanomedicineKevin Kent Vincent Canlas, Hansoo Park School of Integrative Engineering, Chung-Ang University, Seoul, 06974, KoreaCorrespondence: Hansoo Park, Email heyshoo@cau.ac.krAbstract: Angiogenesis is a physiological process of forming new blood vessels that has
Canlas KKV, Park H
doaj
Nucleic Acids Research, 2015 The therapeutic use of antisense and siRNA oligonucleotides has been constrained by the limited ability of these membrane-impermeable molecules to reach their intracellular sites of action.
Bing Yang +10 more
semanticscholar +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, EarlyView.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Molecular Therapy: Nucleic Acids, 2017 Low allelic and clonal variability among endogenous RNAi targets has focused mismatch tolerance studies to RNAi-active guide strands. However, the inherent genomic instability of RNA viruses such as hepatitis C virus (HCV) gives rise to quasi-species ...
Pantazis I. Theotokis +4 more
doaj +1 more source
Smart Nanogels as Enzyme‐Driven Nanomotors for Navigating Viscous Physiological Barriers
Advanced Functional Materials, EarlyView.Two families of urease‐powered nanomotors (NMs), with and without a p‐(2‐hydroxyethyl methacrylate) (p‐HEMA) shell, have been successfully prepared. Both types exhibit effective motion in highly viscous synovial fluid media at low urea concentrations (25 mM).
David Esporrín‐Ubieto +6 more
wiley +1 more source
Genetic Approach for the Fast Discovery of Phenazine Producing Bacteria
Marine Drugs, 2011 A fast and efficient approach was established to identify bacteria possessing the potential to biosynthesize phenazines, which are of special interest regarding their antimicrobial activities.
Johannes F. Imhoff +3 more
doaj +1 more source
Advanced Functional Materials, EarlyView.A sequence‐encoded supramolecular construct containing two accessible toeholds is developed herein for enabling multiple editing operations. By introducing specific input strands, it is possible to selectively erase or rewrite digital content through parallel or series toehold‐mediated strand displacement (PTMSD or STMSD).
Jakub Ossowski +3 more
wiley +1 more source
Inhibition of microRNA function by antimiR oligonucleotides
Silence, 2012 MicroRNAs (miRNAs) have emerged as important post-transcriptional regulators of gene expression in many developmental and cellular processes. Moreover, there is now ample evidence that perturbations in the levels of individual or entire families of ...
J. Stenvang +4 more
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.A miniaturized, label‐free, and enzyme‐free biosensor (miR‐TFT) enables direct electrical detection of microRNA (miRNA) with single‐nucleotide specificity and a detection limit of 0.6 fM. Built on a tri‐channel In2O3/ZnO heterojunction and functionalized with bespoke peptide nucleic acid (PNA) probes, the device is robust, reusable, and compatible with
Wejdan S. Al Ghamdi +5 more
wiley +1 more source
An electrophoretic investigation of the mixture of oligonucleotides formed by the enzymic degradation of deoxyribonucleic acid by deoxyribonuclease [PDF]
, 1951 A. H. Gordon, Peter Reichard
openalex +1 more source