Results 151 to 160 of about 449,240 (358)
Hybridization to surface-bound oligonucleotide probes: Influence of point defects [PDF]
arXiv, 2006 Microarray-based genotyping is based on the high discrimination capability of oligonucleotide probes. For detection of Single Nucleotide Polymorphisms (SNPs) single-base discrimination is required. We investigate how various point-mutations, comprising single base mismatches (MMs), insertions and deletions, affect hybridization of DNA-DNA ...
arxiv
Power-law Signatures and Patchiness in Genechip Oligonucleotide Microarrays [PDF]
arXiv, 2007 . Genechip oligonucleotide microarrays have been used widely for transcriptional profiling of a large number of genes in a given paradigm. Gene expression estimation precedes biological inference and is given as a complex combination of atomic entities on the array called probes.
arxiv
Microarray detection of human parainfluenzavirus 4 infection associated with respiratory failure in an immunocompetent adult. [PDF]
, 2006 A pan-viral DNA microarray, the Virochip (University of California, San Francisco), was used to detect human parainfluenzavirus 4 (HPIV-4) infection in an immunocompetent adult presenting with a life-threatening acute respiratory illness.
Blackburn, Brian G +13 more
core
Advanced Materials Interfaces, EarlyView.The formation of stable clusters of gold nanoparticles with oligonucleotides at different solution conditions is explored. DNA base homogeneity and strand directionality influence the binding with gold nanoparticles leading to interesting clustering behavior that can be relevant for SERS applications.
Shaila Thakur +3 more
wiley +1 more source
Artificial DNA Lattice Fabrication by Non-Complementarity and Geometrical Incompatibility [PDF]
arXiv, 2011 Fabrication of DNA nanostructures primarily follows two fundamental rules. First, DNA oligonucleotides mutually combine by Watson-Crick base pairing rules between complementary base sequences. Second, the geometrical compatibility of the DNA oligonucleotide must match for lattices to form. Here we present a fabrication scheme of DNA nanostructures with
arxiv
Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules
Advanced Materials Interfaces, EarlyView.This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania +2 more
wiley +1 more source
Cooperative Hybridization of Oligonucleotides
Journal of the American Chemical Society, 2010 Nucleic acids have been demonstrated to be versatile nanoscale engineering materials with the construction of dynamic DNA structures, motors, and circuits. These constructions generally rely on the clever use and integration of relatively few reaction mechanisms and design primitives.
openaire +5 more sources
Exploring DNA Functionalization Techniques for Silver Nanoparticles
Advanced Materials Interfaces, EarlyView.This study evaluates four functionalization methods—salt‐aging, pH‐assisted, freezing‐directed, and microwave‐assisted—for attaching DNA strands to 20 nm silver nanoparticles (AgNPs). The resulting DNA‐AgNP conjugates are characterized and colloidal stability and DNA loading are assessed.
Sebastian Freko +3 more
wiley +1 more source
Statistical Thermodynamic Theory for Helix—Coil Transitions Involving Poly- and Oligonucleotides. II. The Case of Partial Binding [PDF]
, 1965 William S. Magee +2 more
openalex +1 more source
Modification and Patterning of Thiolate‐Anchored Self‐Assembled Monolayers with UV Light
Advanced Materials Interfaces, EarlyView.This paper reviews the relevant work regarding the modification and patterning of thiolate‐anchored self‐assembled monolayers with UV light. Performed alone or in combination with a subsequent exchange reaction, introducing specific molecular substituents, this approach enables the preparation of functional binary SAMs and the creation of complex ...
Michael Zharnikov, Andreas Terfort
wiley +1 more source