Results 231 to 240 of about 330,852 (300)

Update and optimization of a multiplex RT-qPCR assay to overcome diagnostic failure in emerging influenza A(H3N2) subclades J.2 and K (Peru, 2024-2026). [PDF]

IJID Reg
Aguilar-Luis MA, Valle-Mendoza JD, Tarazona-Castro Y, Aguilar-Luis D, de Villa EB, Cornejo-Tapia A, Antón A, Andrés C, Laguna-Torres A.   +8 more
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Mapping subcellular microenvironments using oligonucleotide-directed proximity labeling. [PDF]

Curr Opin Chem Biol
Schactler SA, Skiados NG, Gajendragadkar AA, DeLeon LE, Shechner DM.   +4 more
europepmc   +1 more source

Aptamer-based DNA nanoswitches for multiplexed protein detection.

Chem Commun (Camb)
Kovvali S, Beckles CA, Chandrasekaran AR, Halvorsen K.   +3 more
europepmc   +1 more source

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Oligonucleotide Therapy

2017
Oligonucleotides (ONs), the focus of the chapter herein, are mostly known for their utility to selectively manipulate RNA processing by increasing or decreasing target gene levels, in particular by inducing enzymatic RNA degradation, blocking or mimicking miRNAs, inhibiting mRNA translation or modulating pre-mRNA splicing.
Covello, Giuseppina, Denti, Michela Alessandra   +1 more
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Synthesis of Oligonucleotide—Peptide and Oligonucleotide—Protein Conjugates

ChemInform, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
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Immunostimulatory Oligonucleotides

Recent Patents on Inflammation & Allergy Drug Discovery, 2011
RNA-protein interactions have been characterized often. Above all, the proteins which are associated with the studied RNA should be precisely identified. The pharmaceutical compositions containing nucleic acids and/or other compounds can be administered by any suitable route for administering medications. The immunostimulatory oligonucleotides play the
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Oligonucleotide lipoplexes: the influence of oligonucleotide composition on complexation

Biochimica et Biophysica Acta (BBA) - General Subjects, 2001
Despite extensive investigations into oligonucleotide lipoplexes, virtually no work has addressed whether the physicochemical properties of these assemblies vary as a function of the constituent oligonucleotide (ODN) sequence and/or composition. The present study was aimed at answering this question.
Meidan, V.M., Glezer, J., Amariglio, N., Cohen, J.S., Barenholz, Y.   +4 more
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Synthesis of Oligonucleotides and Oligonucleotide Analogues

1989
The aim of this review is to outline modern methods for synthesizing natural oligodeoxynucleotides and certain analogues that may be inhibitors of gene expression. As a consequence, several DNA chemical synthesis methodologies such as the phosphate diester and phosphate triester approaches, which are now primarily only of historical interest, will not ...
openaire   +1 more source