Results 231 to 240 of about 430,879 (296)

Targeted Inhibition of Oncogenic microRNAs miR-21, miR-17, and miR-155 Suppresses Tumor Growth and Modulates Immune Response in Colorectal Cancer. [PDF]

Pharmaceutics
Patutina O, Sen'kova A, Miroshnichenko S, Awad M, Markov O, Gladkikh D, Savin I, Seroklinova E, Zhukov S, Kupryushkin M, Maslov M, Vlassov V, Zenkova M.   +12 more
europepmc   +1 more source

De Novo Complex Genomic Rearrangement Spanning 2q31.1 in a Proband With Congenital Malformations: Genotype–Phenotype Correlation and Development of a CGR Detection Pipeline

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The 2q31 region is commonly associated with pathogenic alleles of the HOXD cluster leading to various clinical phenotypes related to skeletal development. We present a proband with tetralogy of Fallot and multiple congenital anomalies. Genomic variant screening including an in‐house CGR detection pipeline pairing genome sequencing (GS ...
Katherine Helle, Jesse D. Bengtsson, Mira Gandhi, Christopher M. Grochowski, Ming Yin Lun, Neha Sudhir, Shalini N. Jhangiani, Fritz J. Sedlazeck, Seema R. Lalani, Neil A. Hanchard, Claudia M. B. Carvalho   +10 more
wiley   +1 more source

The impact of chemical modifications of antisense oligonucleotides on CTX-M-15 β-lactamase target affinity and expression of ceftriaxone-resistant <i>Escherichia coli</i>. [PDF]

NAR Mol Med
Barry H, Scillia L, Gaubert A, Amrane S, Vialet B, Bégu D, Barthélémy P, Arpin C, Kauss T.   +8 more
europepmc   +1 more source

Nucleic acid base pair open states by hydrogen exchange. [PDF]

Proc Natl Acad Sci U S A
Englander SW.
europepmc   +1 more source

Thermodynamic Profiling Reveals DNA Polymerase Template Binding, Substrate Incorporation, and Exonuclease Function. [PDF]

Int J Mol Sci
Sun Y, Lin W, Fu K, Gao J, Zhao X, He Y, Tian H.   +6 more
europepmc   +1 more source

Mechanistic Insights Into the Retention and Separation Mechanism of Poly(Ethylene Glycol)-Modified Short Oligonucleotides in Anion-Exchange Chromatography. [PDF]

Biotechnol J
Yoshimoto N, Matsumoto T, Ono Y, Kumagai Y.   +3 more
europepmc   +1 more source

Recognition of Non-standard Base Pairs by Triplex-Forming Oligonucleotides Containing an Expanded Genetic Alphabet

Rusling D, Brazzill M, Ma R, Munn K, Prestifilippo L, Pickford A, Kim H, Chen C, Hoshika S, Benner S.   +9 more
europepmc   +1 more source

Chemotherapeutic Spherical Nucleic Acids. [PDF]

ACS Nano
Luo T, Kim YJ, Han Z, Hwang J, Kumari S, Mayer V, Cushing A, Romero RA, Mirkin CA.   +8 more
europepmc   +1 more source

Application of Antisense Oligonucleotides as an Alternative Approach for Gene Expression Control and Functional Studies. [PDF]

Int J Mol Sci
Szukowska A, Żuk M, Sztompke J, Bednarz B, Kaźmierczak U.   +4 more
europepmc   +1 more source