Results 111 to 120 of about 37,441 (229)
ABSTRACT Recombinant protein expression in heterologous biological systems is an expanding field in synthetic biology. Photosynthetic organisms have the potential to provide an efficient low‐cost platform for recombinant protein production because they require minimal growth nutrients and are less susceptible to zoonotic and other contaminants ...
Bharat Kumar Majhi, Anastasios Melis
wiley +1 more source
Insect‐Derived Bioactives for Glycemic Control and Gut Health: A Review
Insect‐derived bioactive compounds (e.g., peptides, polysaccharides) effectively regulate blood glucose through dual mechanisms: directly inhibiting carbohydrate‐digesting enzymes and glucose transporters, and indirectly modulating gut microbiota to enhance intestinal barrier integrity.
Chaoyi Lv +5 more
wiley +1 more source
Oligopeptide sequences of the metal binding domain of CueR metalloregulatory proteins as candidates for toxic metal ion capture [PDF]
Various toxic metal ion resistance systems operate from bacterial level up to higher plants and animals. In bacteria, metalloregulatory proteins are key factors in the control of metal ion level.
Gyurcsik, Béla +2 more
core +2 more sources
This randomized, double‐blind, placebo‐controlled trial demonstrated that probiotic supplementation in individuals with non‐celiac gluten/wheat sensitivity improved tolerance to gluten reintroduction in nearly half of participants. The effect was associated with beneficial shifts in gut microbiome composition and function, including enhanced microbial ...
Ilario Ferrocino +14 more
wiley +1 more source
Residual Chemical Shift Anisotropies in the Structure Determination of Small Molecules
Plasma neutrophil elastase(ELANE) was markedly elevated in patients with alcohol use disorder, indicating a dysregulated protease‐antiprotease inflammatory balance characterised by decreased SERPINA3. ELANE showed excellent diagnostic specificity(AUC = 0.8683), supporting its potential utility as a neuroinflammatory biomarker for AUD.
Nilamoni Nath +3 more
wiley +1 more source
Cyanobacterial toxins are a global threat to aquatic organisms; however, they represent only one group of bioactive cyanobacterial metabolites. Very little is known about the effects of other cyanobacterial products (e.g., non-ribosomal oligopeptides) on
Pawlik-Skowrońska Barbara +2 more
doaj +1 more source
Ab initio simulations of Cu binding sites in the N-terminal region of PrP [PDF]
The prion protein (PrP) binds Cu2+ ions in the octarepeat domain of the N-terminal tail up to full occupancy at pH=7.4. Recent experiments show that the HGGG octarepeat subdomain is responsible for holding the metal bound in a square planar coordination.
Furlan, S. +4 more
core +1 more source
In Silico Approach towards Designing Virtual Oligopeptides for HRSV
HRSV (human respiratory syncytial virus) is a serious cause of lower respiratory tract illness in infants and young children. Designing inhibitors from the proteins involved in virus replication and infection process provides target for new therapeutic ...
Ruchi Jain, Shanmughavel Piramanayagam
doaj +1 more source
A Review of Current Computational Tools for Peptide–Protein Docking
In this review, we compare 14 specialized peptide‐protein docking programs, adaptable small‐molecule docking tools, and emerging AI‐driven approaches. By clarifying how each method works, we offer researchers an accessible guide to selecting the most suitable tools for biochemical studies and peptide‐focused drug discovery.
Fábio G. Martins +2 more
wiley +1 more source
A peptide‐functionalized zwitterionic polymer enables label‐free and noninvasive isolation of human mesenchymal stem cells (hMSCs). The antifouling polymer surface selectively captured hMSCs based on CD44 recognition, achieving high‐purity separation while preserving cell viability and differentiation potential for safe cell transplantation ...
Moe Kato +6 more
wiley +1 more source

