Results 231 to 240 of about 42,078 (262)

Electronic structure analysis of glycine oligopeptides and glycine–tryptophan oligopeptides

Physica E: Low-dimensional Systems and Nanostructures, 2014
Abstract Using the density functional theory (DFT), we have studied the energy gap, charge distribution, density of states and chemical activity of glycine (Gn) oligopeptides and glycine–tryptophan (GWn) oligopeptides. The results show that: (1) with the increasing of Gn residues, the chemical activity of Gn oligopeptides focuses on the terminal ...
Xin Li, Shuai Yu, Mengshi Yang, Can Xu, Yu Wang, Liang Chen   +5 more
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Oligopeptide cyclophilin inhibitors: A reassessment

European Journal of Medicinal Chemistry, 2011
Potent cyclophilin A (CypA) inhibitors such as non-immunosuppressive cyclosporin A (CsA) derivatives have been already used in clinical trials in patients with viral infections. CypA is a peptidyl prolyl cis/trans isomerase (PPIase) that catalyzes slow prolyl bond cis/trans interconversions of the backbone of substrate peptides and proteins.
Michael, Schumann, Günther, Jahreis, Viktoria, Kahlert, Christian, Lücke, Gunter, Fischer   +4 more
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Thermolysin: Kinetic Study with Oligopeptides

European Journal of Biochemistry, 1970
Thermolysin is a well‐known protease which exhibits its specificity against hydrophobic amino acid residues such as l‐leucine, l‐phenylalanine, etc. whose amino groups donate the susceptible peptide bonds (amino‐endopeptidase). The present study was undertaken to investigate the effects of neighboring residues surrounding the sensitive amino acid ...
K, Morihara, H, Tsuzuki
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Metal ion selectivity of oligopeptides

Dalton Trans., 2006
Metal binding affinity and selectivity of peptides are reviewed with a special emphasis on the high structural variety of peptide complexes. The most common structural type of these complexes is built up by the deprotonation and metal ion coordination of subsequent amide groups in the form of fused five-membered chelate rings. The metal ion selectivity
Imre, Sóvágó, Katalin, Osz
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Bacterial oligopeptide-binding proteins

Cellular and Molecular Life Sciences (CMLS), 2003
This review focuses on bacterial oligopeptide-binding proteins, which form part of the oligopeptide transport system belonging to the ATP-binding cassette family of transporters. Depending on the bacterial species, these binding proteins (OppA) capture peptides ranging in size from 2 to 18 amino acids from the environment and pass them on to the other ...
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Conformational Preferences of Proline Oligopeptides

The Journal of Physical Chemistry B, 2006
A conformational study on the terminally blocked proline oligopeptides, Ac-(Pro)(n)()-NMe(2) (n = 2-5), is carried out using the ab initio Hartree-Fock level of theory with the self-consistent reaction field method in the gas phase and in solutions (chloroform, 1-propanol, and water) to explore the preference and transition between polyproline II (PPII)
Young Kee, Kang, Jong Suk, Jhon, Hae Sook, Park   +2 more
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Self-Assembly of Homo Phenylalanine Oligopeptides: Role of Oligopeptide Chain Length

Langmuir
The self-assembly of phenylalanine (F)-based peptides is a critical area of research with potential implications for the development of advanced biomaterials and technologies. Previous studies indicate that homo-oligopeptides with F-X residues (X = 1 to 6) can self-assemble into diverse nano-microstructures, but the role of oligopeptide chain length on
Safaa Kader, Muntadher Sultan, Esmaiel Jabbari   +2 more
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Vibrational optical activity of oligopeptides

Biopolymers, 1995
AbstractVibrational optical activity (VOA) is a relatively newspectroscopic technique, which has two principal manifestations, ir vibrational CD and vibrational Raman optical activity. Progress in the study of oligopeptides using both of these forms of VOA is reviewed from the perspective of theoretical and instrumental techniques, spectral results ...
T B, Freedman, L A, Nafie, T A, Keiderling   +2 more
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Molecular Radical Cations of Oligopeptides

The Journal of Physical Chemistry B, 2000
An unprecedented method of producing molecular radical cations of oligopeptides in the gas phase has been discovered. Electrospraying a methanolic mixture of a Cu(II)−amine complex, e.g., CuII(dien)(NO3)2 (where dien = diethylenetriamine), and an oligopeptide (M) yields the [CuII(dien)M]•2+ ion, whose collision-induced dissociation (CID) produces [CuI ...
Hopkinson, AC, Chu, IK, Rodriquez, CF, Lau, TC, Michael Siu, KW   +4 more
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Interaction of Oligopeptides with Heparin

Macromolecular Symposia, 1998
Macromolecular drugs, such as heparin and insulin, are easily degraded by acids and enzymes in the GI tract and do not readily penetrate the lipophilic biomembranes, resulting in low bioavailability by the oral route.1–3 Currently, these drugs have to be administered by injections. Proteinoids,4–8 which can form microspheres with certain macromolecular
Ruifeng Zhao, Mamoru Haratake, Raphael M. Ottenbrite   +2 more
openaire   +1 more source