Results 81 to 90 of about 22,136 (209)
Knowledge and Management of Aquatic Ecosystems, 2018 Cyanobacterial toxins are a global threat to aquatic organisms; however, they represent only one group of bioactive cyanobacterial metabolites. Very little is known about the effects of other cyanobacterial products (e.g., non-ribosomal oligopeptides) on
Pawlik-Skowrońska Barbara +2 more
doaj +1 more source
Mapping the Substrate Specificity Landscape of PAD2 and PAD4 Enzymes
ChemBioChem, Volume 27, Issue 11, 15 June 2026.Protein citrullination, driven by peptidyl arginine deiminases (PAD2, PAD4), is linked to multiple diseases. Using a combinatorial peptide library and advanced mass spectrometry, we reveal distinct substrate selectivity profiles of PAD2 and PAD4. While PAD2 broadly citrullinates arginine‐containing peptides, PAD4 is highly sequence‐restricted, with ...
Adina Borbély +6 more
wiley +1 more source
In Silico Approach towards Designing Virtual Oligopeptides for HRSV
The Scientific World Journal, 2014 HRSV (human respiratory syncytial virus) is a serious cause of lower respiratory tract illness in infants and young children. Designing inhibitors from the proteins involved in virus replication and infection process provides target for new therapeutic ...
Ruchi Jain, Shanmughavel Piramanayagam
doaj +1 more source
Advanced Science, Volume 13, Issue 36, 29 June 2026.ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley +1 more source
Ion‐Pairing and Counterion Effects in Contemporary Photochemistry
Angewandte Chemie Novit, Volume 2, Issue 2, June 2026.Ion‐pairing and counterion effects have emerged as fundamental yet underexplored determinants of photochemical behavior. Far from inert, counterions, and Coulombic interactions modulate excited‐state dynamics, quenching efficiencies, emission, and catalytic pathways.
Matthias Schmitz, Christoph Kerzig
wiley +1 more source
Intravenous lanadelumab for the treatment of moderately ill COVID‐19 patients
British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1685-1695, June 2026.Aims Kallikrein‐kinin system (KKS) dysregulation is hypothesized to play a pathogenetic role in COVID‐19‐associated pulmonary oedema. To investigate the efficacy and safety of intravenous lanadelumab, a monoclonal antibody that inhibits plasma kallikrein, in COVID‐19, we conducted a phase 2, open‐label, randomized‐controlled, proof‐of‐concept ...
Job J. Engel +12 more
wiley +1 more source
The Canadian Journal of Chemical Engineering, Volume 104, Issue 6, Page 2786-2796, June 2026.This study quantifies the effects of different soils found in the food processing environment on the efficiency of pulsed‐xenon UV disinfection. Abstract Listeria monocytogenes is a foodborne illness that poses a significant threat to human health in young, old, and immunocompromised persons and accordingly, prevention of Listeria contamination is of ...
Nazanin Yasoubi +2 more
wiley +1 more source
MccB‐catalyzed C‐terminal Thioesterification for Protein Bioconjugation
Current Protocols, Volume 6, Issue 6, June 2026.Abstract Protein bioconjugation enables the installation of functional groups, probes, and payloads that cannot be genetically encoded, thereby enabling the study and manipulation of biological systems. An important class of intermediates in protein bioconjugation is C‐terminal protein α‐thioesters, which are kinetically stable yet thermodynamically ...
Di Yang, Amy M. Weeks
wiley +1 more source
Current Protocols, Volume 6, Issue 6, June 2026.Abstract Immunohistochemistry (IHC) is a widely used technique for the identification, localization, and analysis of protein expression in tissues, playing a critical role in pathological diagnosis and validation of data derived from molecular biology. Despite its well‐established use in mammalian tissues, applying IHC to fish still presents challenges,
Erika Stefani Perez +5 more
wiley +1 more source
Ecology and Evolution, Volume 16, Issue 6, June 2026.Despite their evolutionary relatedness to malaria parasites that infect humans, wildlife Plasmodium—particularly those that infect birds and lizards—are understudied, leaving their vast genetic diversity to be explored. By assembling parasite transcriptomes from Plasmodium‐infected lizard blood, we provide the first evidence that lizard‐infective ...
Sarah J. Pangburn +4 more
wiley +1 more source