Results 61 to 70 of about 22,170 (201)

The Influence of Peptidases in Intestinal Brush Border Membranes on the Absorption of Oligopeptides from Whey Protein Hydrolysate: An Ex Vivo Study Using an Ussing Chamber

Foods, 2020
For many years, it was believed that only amino acids, dipeptides, and tripeptides could be absorbed and thus reach the bloodstream. Nowadays, the bioavailability of oligopeptides is also considered possible, leading to new research.
Luísa Ozorio, Caroline Mellinger-Silva, Lourdes M. C. Cabral, Julien Jardin, Gaelle Boudry, Didier Dupont   +5 more
doaj   +1 more source

Peripheral targets for neuropathic pain

British Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour, Cosmin I. Ciotu, Felix J. Resch, Michael J. M. Fischer   +3 more
wiley   +1 more source

Intracellular Pool of Low- and Medium-Molecular-Weight Substances as a Nonspecific Integrative Indicator of Immunometabolism

Журнал медико-биологических исследований
Low- and medium-molecular-weight substances (LMMWS) and oligopeptides (OPs) constitute a pool of heterogeneous molecules formed during metabolic processes. These substances have been found to play a significant role in the development of metabolic shifts
Olga V. Zubatkina, Sergey D. Kruglov
doaj   +1 more source

Primary Step Towards In Situ Detection of Chemical Biomarkers in the UNIVERSE via Liquid-Based Analytical System: Development of an Automated Online Trapping/Liquid Chromatography System

Molecules, 2019
The search for biomarkers in our solar system is a fundamental challenge for the space research community. It encompasses major difficulties linked to their very low concentration levels, their ambiguous origins (biotic or abiotic), as well as their ...
Thomas Ribette, Bertrand Leroux, Balkis Eddhif, Audrey Allavena, Marc David, Robert Sternberg, Pauline Poinot, Claude Geffroy-Rodier   +7 more
doaj   +1 more source

Bio‐active designed peptide for hair keratin strengthening

International Journal of Cosmetic Science, EarlyView.
Bioactive tripeptides through in silico screening revealed KCV (Tripeptide‐132) as the most promising keratin‐targeting candidate. Experimental studies confirmed its superior hair‐strengthening performance with 44% tensile strength enhancement, 50% breakage reduction, improved surface integrity and fibre penetration.
Chan‐Su Rha, Byeong Gyu In, Kilsun Myoung, Chaeyeon Song, Eun‐Soo Lee, Heung Soo Baek, Won Seok Park   +6 more
wiley   +1 more source

Isolation and characterization of peptides from blood serum of patients with multiple sclerosis

Біологічні студії, 2015
In order to find novel molecular markers of multiple sclerosis we developed a scheme of oligopeptides’ isolation including their extraction from blood serum with 10 % trichloroacetic acid, followed by precipitation of soluble substances with acetone in ...
S. Myronovskij, N. Negrych, T. Nehrych, M. Starykovych, V. Tkachenko, V. Yukalo, L. Storozh, O. Nemchenko, G. Lavryk, R. Stoika, Y. Kit   +10 more
doaj   +1 more source

Evaluating the In Vitro Digestibility of Black Soldier Fly (Hermetia illucens L.) Larvae as Potential Feed Ingredient in Dairy Cattle Silage‐Based Diets: A Focus on Proteins

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Dietary protein has a substantial economic impact on cattle feed, and it is also a critical component for animal growth and productivity. Several environmental issues related to soybeans have led to an increased interest in novel protein sources, such as insects.
Maria Giulia Bonomini, Marica Simoni, Matteo Profeti, Federico Righi, Augusta Caligiani   +4 more
wiley   +1 more source

Bioactive oligopeptides and the application in skin regeneration and rejuvenation

Journal of Applied Biomaterials & Functional Materials
Oligopeptides, composed of 2–10 amino acid residues, are protein fragments with unique structural characteristics, including small molecular size, high biocompatibility, and modifiable functional groups.
Qiulin He, Youguo Liao, Yaru Wu, Huahui Zhang, Xiaohui Long, Yuxiang Zhang   +5 more
doaj   +1 more source

Iron homeostasis in the annual and perennial stem zones of Arabis alpina

Plant Biology, EarlyView.
Iron accumulates in secondary growth tissues in the perennial stem zone and is correlated with particular gene expression patterns in the perennial model plant Arabis alpina. Abstract Plants store nutrients, including the micronutrient iron, in bioavailable forms to support growth in subsequent seasons. The perennial lifestyle is preponderant in nature.
A. Sergeeva, H.‐J. Mai, P. Bauer
wiley   +1 more source

Time‐series multi‐omics analysis of micronutrient stress in Sorghum bicolor reveals iron and zinc crosstalk and regulatory network conservation

Plant Biology, EarlyView.
Overlap between Fe and Zn responsive gene regulatory networks (GRNs) were found, indicative of micronutrient crosstalk, and conservation of root and leaf GRNs and genes suggests strong constraint on homeostasis networks in plants. Abstract Micronutrient stress impacts growth, biomass production, and grain yield in crops.
A. Mishra, A. Bhat, S. Kumari, R. Sharma, J. Braynen, D. Tadesse, S. El Alaoui, S. Seaver, N. Grosjean, D. Ware, M. Xie, T. Paape   +11 more
wiley   +1 more source