Results 41 to 50 of about 22,136 (209)

The EROP-Moscow oligopeptide database [PDF]

Nucleic Acids Research, 2006
Natural oligopeptides may regulate nearly all vital processes. To date, the chemical structures of nearly 6000 oligopeptides have been identified from >1000 organisms representing all the biological kingdoms. We have compiled the known physical, chemical and biological properties of these oligopeptides--whether synthesized on ribosomes or by non ...
Alexander A. Zamyatnin, Alexander S. Borchikov, Michail G. Vladimirov, Olga L. Voronina   +3 more
openaire   +2 more sources

Late‐Stage Functionalization of Peptides on the Solid Phase

Angewandte Chemie International Edition, EarlyView.
Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner, Truc Lam Pham, Franziska Thomas   +2 more
wiley   +1 more source

Milk oligopeptide inhibition of (α)-tocopherol fortified linoleic acid oxidation

International Journal of Food Properties, 2019
This study investigated the effect of milk oligopeptides and (α)-tocopherol on inhibition of linoleic acid oxidation using Fe2+-vitamin C induced linoleic acid oxidation model through analysis of malondialdehyde, peroxide value, and conjugated diene and ...
Haina Yuan, Jinyan Gong, Kun Tang, Jinge Huang, Gongnian Xiao, Jianmin Lv   +5 more
doaj   +1 more source

Natural Antibodies Produced in Vaccinated Patients and COVID-19 Convalescents Recognize and Hydrolyze Oligopeptides Corresponding to the S-Protein of SARS-CoV-2

Vaccines, 2023
The S-protein is the major antigen of the SARS-CoV-2 virus, against which protective antibodies are generated. The S-protein gene was used in adenoviral vectors and mRNA vaccines against COVID-19.
Anna M. Timofeeva, Sergey E. Sedykh, Tatyana A. Sedykh, Georgy A. Nevinsky   +3 more
doaj   +1 more source

Protein hydrolysates in cell culture: Toward multi‐omics characterization

Biotechnology Progress, EarlyView.
While protein hydrolysates are widely used in cell culture applications, they remain undefined and variable products. Multi‐omic characterization evaluating composition and function can transition hydrolysates toward semi‐defined media components.
Michelle Combe, Brandon M. Wrage, Angel Varela‐Rohena, Stanislav Sokolenko   +3 more
wiley   +1 more source

Efficacy and safety of μ1-opioid receptor agonist (Taphalgin®) for emergency analgesia in outpatient practice

Saudi Journal of Anaesthesia
Background: A new peptide analgesic, a highly selective μ1-opioid receptor agonist (Taphalgin®) has shown the high efficacy in treating acute postoperative and chronic oncological pain, it appears to be a promising option for the treatment of patients ...
Alexey G. Voloshin, Kseniya N. Avetisova, Natal’ya V. Smirnova   +2 more
doaj   +1 more source

Indices of peroxidation of lipids of biological membranes and endogenous intoxication in patients with psoriasis on the background of chronic viral hepatitis С

Vestnik Dermatologii i Venerologii, 2019
Aim. To study the features of lipid peroxidation of biological membranes and accumulation of toxic metabolites in the body of patients with psoriasis, depending on the presence of concomitant chronic viral hepatitis C.Materials and methods. In the survey,
M. Yu. Marzhokhova, Ashour Ahmad Mahmud Hussein, A. R. Marzhokhova   +2 more
doaj   +1 more source

Bond-specific fragmentation of oligopeptides via electronic stopping of swift heavy ions in molecular films

Scientific Reports, 2022
Highly bond-specific fragmentation of oligopeptides induced by swift heavy ion (SHI) irradiation was investigated by means of mass spectrometry. In pronounced contrast to measurements of samples irradiated with keV ions, oligopeptides which were exposed ...
P. Schneider, P. Keller, I. Schubert, M. Bender, C. Trautmann, M. Dürr   +5 more
doaj   +1 more source

Self-Assembly of the Dipeptide L-Alanyl-L-Phenylalanine under the Action of Methanol Vapor with the Formation of Micro- and Nanostructures

Учёные записки Казанского университета: Серия Естественные науки, 2023
The mechanism of self-assembly by short-chain peptides (oligopeptides) – the process by which their molecules spontaneously form an ordered structure – has received much attention recently.
A. S. Morozova, E. O. Kudryavtseva, S. A. Ziganshina, M. A. Ziganshin, A. A. Bukharaev   +4 more
doaj   +1 more source

Substrate‐Selective Inhibition of the SARS‐CoV‐2 Papain‐Like Protease: Inhibition of Hydrolysis of Human Over Viral Substrates

Chemistry – A European Journal, EarlyView.
The SARS‐CoV‐2 papain‐like protease (PLpro) is a medicinal chemistry target. Here we report mass spectrometry assays employing oligopeptide substrates based on the sequences of the viral polyproteins 1a/1ab and on an ISG15‐modified human protein, which enabled the identification of substrate‐selective PLpro inhibitors.
Sakshi Sharma, Peter A. C. Wing, Wojtek Treyde, Shyam Basak, Simeon D. Draganov, Taylah Andrews‐Clark, Eidarus Salah, Petra Lukacik, Claire Strain‐Damerell, Adán Pinto‐Fernández, Martin A. Walsh, Fernanda Duarte, Christopher J. Schofield, Lennart Brewitz   +13 more
wiley   +1 more source