Results 61 to 70 of about 1,327 (120)

Frequency and Prognostic Impact of Local Ablation Therapy for Oligoprogression in Non‐Small Cell Lung Cancer

Thoracic Cancer
Background During the systemic treatment of patients with non‐small cell lung cancer (NSCLC), oligoprogression (OP), a condition in which most lesions remain controlled while a few progress or develop, has recently attracted attention.
Daisuke Morinaga, Jun Sakakibara‐Konishi, Ryohei Kamada, Masahiro Kashima, Kosuke Tsuji, Shotaro Ito, Megumi Furuta, Tetsuaki Shoji, Yuta Takashima, Hidenori Kitai, Yasuyuki Ikezawa, Hiroshi Taguchi, Tatsuya Kato, Yoshiki Shinomiya, Kanako C Hatanaka, Yutaka Hatanaka, Satoshi Konno   +16 more
doaj   +1 more source

Efficacy of radiotherapy in stabilization of oligoprogressive lesions of malignant melanoma treated with immunotherapy

Reports of Practical Oncology and Radiotherapy
BACKGROUND: This study aims to evaluate the effectiveness of radiotherapy (RT) in stabilizing oligoprogressive disease (OPD) in melanoma patients undergoing immunotherapy.
Martin Palkovsky, Alzbeta Hlodakova, Jindrich Kopecky, Marek Pasek, Jiri Svec, Monika Arenbergerova, Petr Arenberger, Renata Soumarova   +7 more
doaj   +1 more source

Impact of local treatment on survival outcomes in patients with metastatic lung cancer with oligoprogression undergoing immunotherapy

Swiss Medical Weekly
PURPOSE: Immune checkpoint inhibitors have revolutionised the management of non-small cell lung cancer (NSCLC) without oncogenic addictions and have improved its prognosis. A manifestation of acquired resistance to immunotherapy, which is typically seen
Barbara Domenach, Valentine Mismetti, Wafa Bouleftour, Anne Bareille, Olivier Tiffet, Anne-Laure Desage, Pierre Fournel   +6 more
doaj   +1 more source

Complex situations in lung cancer: multifocal disease, oligoprogression and oligorecurrence

European Respiratory Review
With the emergence of lung cancer screening programmes and newly detected localised and multifocal disease, novel treatment compounds and multimodal treatment approaches, the treatment landscape of non-small cell lung cancer is becoming increasingly ...
Raphael Werner, Nina Steinmann, Herbert Decaluwe, Hiroshi Date, Dirk De Ruysscher, Isabelle Opitz   +5 more
doaj   +1 more source

Efficacy and safety of radiotherapy to delay second-line systemic therapy in patients with oligoprogressive hepatocellular carcinoma: study protocol of a multicentre, single-arm, phase II trial

Therapeutic Advances in Medical Oncology
Background: Hepatocellular carcinoma (HCC) is a highly aggressive cancer with a paucity of efficacious treatment options, particularly in advanced stages following first-line systemic therapy (FLST).
Haohua Wang, Xiang Zhang, Kunli Zhu, Shumei Jiang, Tianxing Liu, Rui Feng, Xue Dou, Lei Xu, Junyi He, Fang Shi, Jinbo Yue   +10 more
doaj   +1 more source

Oligometastatic NSCLC: Current Perspectives and Future Challenges

Current Oncology
Oligometastatic non-small cell lung cancer (NSCLC) represents a separate entity with a different biology and prognosis compared to stage IV NSCLC. Challenges range from the very definition of oligometastatic disease to the timing and techniques of local ...
Sara Torresan, Jacopo Costa, Carol Zanchetta, Lorenzo De Marchi, Simona Rizzato, Francesco Cortiula   +5 more
doaj   +1 more source

Local ablative treatment and continuation of systemic therapy for oligoprogressive metastatic breast cancer: a retrospective cohort study

Cancer Treatment and Research Communications
Introduction: Patients with metastatic breast cancer (MBC) typically receive palliative systemic therapy until unmanageable toxicity or progression, at which point treatment is changed.
Cornelia A.M. Almekinders, Tess I.M. Snellen, Annemiek van Ommen-Nijhof, Tessa G. Steenbruggen, Elisabeth G. Klompenhouwer, Niels F.M. Kok, Koert F.D. Kuhlmann, Frederieke van Duijnhoven, Monique E.M.M. Bos, Terry G. Wiersma, Vincent O. Dezentjé, Gabe S. Sonke   +11 more
doaj   +1 more source

Computed tomography guided high dose rate brachytherapy for induced oligoprogression of colorectal cancer liver metastases

Scientific Reports
Data on the efficacy of computer tomography guided brachytherapy (CT-BRT) for limited liver metastases is lacking; to assess CT-BRT’s role in inducedoligoprogression in colorectal cancer (CRC), we performed a retrospective cohort study on CRC patients ...
Paweł Cisek, Łukasz Kuncman, Barbara Alicja Jereczek-Fossa, Ewa Wojtyna, Magdalena Orzechowska, Sylwia Sroka, Izabela Kordzińska-Cisek, Jacek Fijuth, Mateusz Bilski   +8 more
doaj   +1 more source

Patterns of failure and the subsequent treatment after progression on first-line immunotherapy monotherapy in advanced non-small cell lung cancer: a retrospective study

BMC Cancer
Background Immune checkpoint inhibitors (ICIs) have become the recommended first-line treatment for advanced non-small cell lung cancer (NSCLC) without driver gene mutations. However, data on the failure patterns of first-line ICIs monotherapy is limited,
Jia-Yi Deng, Ming-Yi Yang, Xiao-Rong Yang, Zhi-Hong Chen, Chong-Rui Xu, Qing Zhou   +5 more
doaj   +1 more source

Metastatic Malignant Mesothelioma of the Tunica Vaginalis Testis Treated With Sequential Immunotherapy, Chemotherapy, and Radiotherapy With Prolonged Disease Stabilisation: A Case Report. [PDF]

Cureus
Mathiyalagan N, Khan S, Pascoe A, Chauhan M, Sarwar MA, Abuzahra WN, Azad S, Mohindru G.   +7 more
europepmc   +1 more source