Results 41 to 50 of about 1,653 (153)

Stereotactic ablative radiotherapy for acquired resistance to EGFR therapy in metastatic non-small cell lung cancer

Frontiers in Oncology, 2023
The advent of targeted therapy has transformed the treatment paradigm and survival of patients with metastatic non-small cell lung cancer (NSCLC) with driver mutations.
Rodolfo Chicas-Sett, Juan Castilla Martinez, Abrahan Hernández Blanquisett, Juan Zafra, Juan Zafra, Juan Zafra, Jorge Pastor-Peidro   +6 more
doaj   +1 more source

Successful Treatment of a Resistant Subclone in ALK-Rearranged NSCLC

Case Reports in Oncology, 2020
Anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitors (TKIs) are established effective therapies in patients with ALK-rearranged advanced non-small-cell lung cancer (NSCLC).
David König, Urs R. Meier, Bernd Klaeser, Spasenija Savic, Miklos Pless   +4 more
doaj   +1 more source

Oligometastatic NSCLC: Current Perspectives and Future Challenges

Current Oncology
Oligometastatic non-small cell lung cancer (NSCLC) represents a separate entity with a different biology and prognosis compared to stage IV NSCLC. Challenges range from the very definition of oligometastatic disease to the timing and techniques of local ...
Sara Torresan, Jacopo Costa, Carol Zanchetta, Lorenzo De Marchi, Simona Rizzato, Francesco Cortiula   +5 more
doaj   +1 more source

Dataset related to article "The impact of stereotactic ablative radiotherapy on oligoprogressive metastases from renal cell carcinoma"

, 2023
<p>This record contains raw data related to article "The impact of stereotactic ablative radiotherapy on oligoprogressive metastases from renal cell carcinoma"</p><p><strong> Abstract</strong></p><p> ...
Tomatis, Stefano, franzese, ciro, Lo faro, Lorenzo, Badalamenti, Marco, Di Cristina, Luciana, Massaro, Maria, Bellu, Luisa, Navarria, Pierina, Comito, Tiziana, Franceschini, Davide, Clerici, Elena, Teriaca, Maria Ausilia, Marini, Beatrice, Scorsetti, Marta, Baldaccini, Davide   +14 more
core   +1 more source

Stereotactic Body Radiation Therapy for the Treatment of Locally Recurrent and Oligoprogressive Non-Small Cell Lung Cancer: A Single Institution Experience

Frontiers in Oncology, 2022
ObjectivesTo investigate the efficacy and safety of lung stereotactic body radiation therapy (SBRT) for non-small cell lung cancer (NSCLC) including oligorecurrent and oligoprogressive disease.MethodsSingle-institution retrospective analysis of 60 NSCLC ...
Leah M. Katz, Victor Ng, S. Peter Wu, Sherry Yan, David Grew, Samuel Shin, Nicholas W. Colangelo, Allison McCarthy, Harvey I. Pass, Abraham Chachoua, Peter B. Schiff   +10 more
doaj   +1 more source

Local ablative therapy of oligoprogressive TKI-treated thyroid cancer

, 2019
Metastatic cancer patients generally respond well to treatment with tyrosine kinase inhibitors (TKIs). However, TKI resistance occurs in almost all cases and often leads to a change in treatment.
SESSA, FRANCESCA, Porcelli T., Salvatore Domenico, Luongo C.   +3 more
core   +1 more source

Management of one patient with oligoprogressive thyroid cancer during treatment with lenvatinib

, 2019
Recent thyroid cancer guidelines found it reasonable to use local therapies during treatment with tyrosine kinase inhibitors (TKIs) in selected patients with oligoprogressive disease, namely, in the presence of a single progressing lesion in an otherwise
Porcelli T., Salvatore Domenico, GAMBALE, CARLA, Luongo C., Sessa F.   +4 more
core   +1 more source

Liver Metastases from Colorectal Cancer: From Pathogenesis to Current Treatment

MedComm, Volume 7, Issue 10, October 2026.
The liver is not merely a passive recipient of disseminated tumor cells, but a unique metastatic organ shaped by anatomical, metabolic, and immunological characteristics that support tumor colonization. Increasing evidence indicates that colorectal cancer liver metastasis development is driven by dynamic interactions between tumor intrinsic programs ...
Jialiang Fan, Huiru Zhang, Deyang Kong, Yu Sun, Shuaibing Lu, Wenjing Yang, Renshen Xiang, Qi Zhang, Wei Pei, Haizeng Zhang, Lin Feng   +10 more
wiley   +1 more source

Treatment Approaches for Oligoprogressive Non-Small Cell Lung Cancer: A Review of Ablative Radiotherapy. [PDF]

Cancers (Basel)
Oligoprogressive disease refers to the setting of a prior or ongoing receipt of systemic therapy, with typically up to three metastatic areas having increased in size and/or avidity compared to the start of the systemic therapy.
Gombrich W, Eustace N, Liu Y, Muddasani R, Rock A, Salgia R, Williams T, Malhotra J, Lee P, Amini A.   +9 more
europepmc   +2 more sources

Dose-escalated radiotherapy with simultaneous integrated boost for bone metastases in selected patients with assumed favourable prognosis

Radiology and Oncology, 2022
Stereotactic body radiotherapy (SBRT) concepts for dose escalation are increasingly used for bone metastases in patients with oligometastatic or oligoprogressive disease.
Potkrajcic Vlatko, Mueller Arndt-Christian, Frey Bettina, Gani Cihan, Zips Daniel, Hoffmann Ruediger, Frantz Sandra, Warm Verena, Paulsen Frank, Eckert Franziska   +9 more
doaj   +1 more source