Results 21 to 30 of about 403,843 (306)

Automated Platform for the Synthesis of Heparan Sulfate Oligosaccharide Libraries for Decoding Glycosaminoglycan-Protein Interactions

, 2022
Glycosaminoglycans (GAGs) are abundant, ubiquitous carbohydrates in biology, yet their structural complexity has limited an understanding of their biological roles and structure-function relationships.
Lei, Wang, Guowei, Su, Mallory, Kern, Alexander, Sorum, Jian, Liu, Xuefei, Huang, Nicola, Pohl, Linda, Hsieh-Wilson, Bo-Shun, Huang   +8 more
core   +1 more source

Sugar Type Discrimination in O-glycosylation Based on Protein Primary Sequences

Journal of Biomechanical Science and Engineering, 2013
Glycosylation is one of the most important protein post-translational modifications. O-glycosylation plays important roles in biological functions. There are several variations of O-glycosylation, with each having a different function.
Kenji ETCHUYA, Yuri MUKAI
doaj   +1 more source

Synthesis of Heparin Oligosaccharides. [PDF]

ChemInform, 2003
An efficient preparation of rare 2-O-benzoyl-3-O-benzyl-1,6-anhydro-beta-l-idopyranose from commercially available diacetone alpha-d-glucose in five straightforward steps is described here. With this key building block in hand, the total syntheses of heparin oligosaccharides with three, five, seven, and nine sugar units are successfully carried out.
Jinq-Chyi, Lee, Xin-An, Lu, Suvarn S, Kulkarni, Yuh-Sheng, Wen, Shang-Cheng, Hung   +4 more
openaire   +2 more sources

CIP103108 LPS Core Oligosaccharide

, 2021
International audienceAcetobacter pasteurianus, a member of the Alphaproteobacteria, is an acetic acid-producing bacterium present on sugar-rich substrates such as such as fruits, flowers and vegetables and traditionally used in the production of ...
Pallach, Mateusz, Ferran Nieto Fabregat, Gully, Djamel, Duda, Katarzyna, Mateusz Pallach, Djamel Gully, Katarzyna A. Duda, Silipo, Alba, Eric Giraud, Nieto Fabregat, Ferran, Roberta Marchetti, Marchetti, Roberta, Molinaro, Antonio, Alba Silipo, Giraud, Eric, Antonio Molinaro   +15 more
core   +1 more source

Classical and novel strategies to develop a Shigella glycoconjugate vaccine: from concept to efficacy in human

Human Vaccines & Immunotherapeutics, 2019
Shigella are gram-negative bacteria that cause severe diarrhea and dysentery, with a high level of antimicrobial resistance. Disease-induced protection against reinfection in Shigella-endemic areas provides convincing evidence on the feasibility of a ...
Louis-Antoine Barel, Laurence A. Mulard
doaj   +1 more source

Precise Structure and Anticoagulant Activity of Fucosylated Glycosaminoglycan from Apostichopus japonicus: Analysis of Its Depolymerized Fragments

Marine Drugs, 2019
Apostichopus japonicus is one of the most economically important species in sea cucumber aquaculture in China. Fucosylated glycosaminoglycan from A. japonicus (AjFG) has shown multiple pharmacological activities.
Ruowei Guan, Yuan Peng, Lutan Zhou, Wenqi Zheng, Xixi Liu, Pin Wang, Qingxia Yuan, Na Gao, Longyan Zhao, Jinhua Zhao   +9 more
doaj   +1 more source

Oligosaccharide release from frozen and paraffin-wax-embedded archival tissues.

, 1996
Altered glycosylation is a feature of many solid tissue diseases such as ulcerative colitis, Crohn's disease, cancer, and connective tissue disorders. Conventionally, oligosaccharide changes have been studied by immunohistochemical techniques.
Streets, A.J., Brooks, S.A., Leathem, A.J., Dwek, M.V., Harvey, D.J.   +4 more
core   +1 more source

Preparation and characterization of EGCase I, applicable to the comprehensive analysis of GSLs, using a rhodococcal expression system

Journal of Lipid Research, 2012
Endoglycoceramidase (EGCase) is a glycosidase capable of hydrolyzing the β -glycosidic linkage between the oligosaccharides and ceramides of glycosphingolipids (GSLs).
Yohei Ishibashi, Utaro Kobayashi, Atsushi Hijikata, Keishi Sakaguchi, Hatsumi M. Goda, Tomohiro Tamura, Nozomu Okino, Makoto Ito   +7 more
doaj   +1 more source

Physiological response of bacillus licheniformis NCIMB 8874to oligosaccharide elicitors [PDF]

, 2012
The mechanism by which certain oligosaccharides elicit overproduction of secondary metabolites in Bacillus licheniformis was investigated. Mannan oligosaccharides (MO) derived from locust bean gum, and oligoguluronate (OG) and oligomannuronate (OM) from ...
Reffatti, P.
core   +1 more source

A New Chemical Approach to Human ABO Histo-Blood Group Type 2 Antigens

Molecules, 2013
A new chemical approach to synthesizing human ABO histo-blood type 2 antigenic determinants was developed. N-Phthaloyl-protected lactosaminyl thioglycoside derived from lactulose via the Heyns rearrangement was employed to obtain a type 2 core ...
Atsushi Hara, Akihiro Imamura, Hiromune Ando, Hideharu Ishida, Makoto Kiso   +4 more
doaj   +1 more source