Unraveling Heparan Sulfate Proteoglycan Binding Motif for Cancer Cell Selectivity
Membrane heparan sulfate proteoglycans (HSPG) regulate cell proliferation, migration, and differentiation and are therefore considered key players in cancer cell development processes.
Jlenia Brunetti +9 more
doaj +1 more source
The structure of a resuscitation-promoting factor domain from Mycobacterium tuberculosis shows homology to lysozymes [PDF]
Resuscitation-promoting factor (RPF) proteins reactivate stationary-phase cultures of (G+C)-rich Gram-positive bacteria including the causative agent of tuberculosis, Mycobacterium tuberculosis.
AT Brunger +27 more
core +2 more sources
Amadori Products - Substrates and Inhibitors for Intestinal Brush Border Glycosidases
The effect of oligosaccharide-derived Amadori products on intestinal disaccharidases was investigated to answer the question, whether these products, ingested in relevant amounts with the daily diet, are degraded by carbohydrate-digesting enzymes and in ...
A. Seidowski, D. Lunow, T. Henle
doaj +1 more source
Active Site Mapping of Xylan-Deconstructing Enzymes with Arabinoxylan Oligosaccharides Produced by Automated Glycan Assembly [PDF]
Xylan-degrading enzymes are crucial for the deconstruction of hemicellulosic biomass, making the hydrolysis products available for various industrial applications such as the production of biofuel.
de Kruijff, Goswinus H. M. +6 more
core +1 more source
Different types of soluble fermentable dietary fibre decrease food intake, body weight gain and adiposity in young adult male rats [PDF]
We thank Donna Wallace and the Rowett Animal House staff for the daily care of experimental rats, body weight and food intake measurements and MRI scanning, Vivien Buchan and Donna Henderson of the Rowett Analytical Department for proximate analyses and ...
Adam, Clare L +7 more
core +2 more sources
Shotgun ion mobility mass spectrometry sequencing of heparan sulfate saccharides [PDF]
Despite evident regulatory roles of heparan sulfate (HS) saccharides in numerous biological processes, definitive information on the bioactive sequences of these polymers is lacking, with only a handful of natural structures sequenced to date.
Grabarics, Márkó +9 more
core +1 more source
Maternal fucosyltransferase 2 status affects the gut bifidobacterial communities of breastfed infants. [PDF]
BackgroundIndividuals with inactive alleles of the fucosyltransferase 2 gene (FUT2; termed the 'secretor' gene) are common in many populations. Some members of the genus Bifidobacterium, common infant gut commensals, are known to consume 2'-fucosylated ...
German, J Bruce +11 more
core +1 more source
Sugar Type Discrimination in O-glycosylation Based on Protein Primary Sequences
Glycosylation is one of the most important protein post-translational modifications. O-glycosylation plays important roles in biological functions. There are several variations of O-glycosylation, with each having a different function.
Kenji ETCHUYA, Yuri MUKAI
doaj +1 more source
Protein-carbohydrate interactions during fertilization [PDF]
Interaction between gametes during fertilization is at least in part regulated by carbohydrate moieties of the zona pellucida (ZP) and carbohydrate binding proteins of the sperm surface. This review focuses on the protein-carbohydrate interactions during
Kolle, S., Plendl, J., Sinowatz, Fred
core +1 more source
Comparative composition, diversity, and abundance of oligosaccharides in early lactation milk from commercial dairy and beef cows. [PDF]
Prebiotics are nondigestible dietary ingredients, usually oligosaccharides (OS), that provide a health benefit to the host by directly modulating the gut microbiota.
Barile, Daniela +4 more
core +2 more sources

