Taiwanese Journal of Obstetrics & Gynecology, 2022 Objective: We present our study about the significance of karyotyping and azoospermia factor(AZF) analysis in patients with azoospermia or oligozoospermia.
Shin-Wen Chen +4 more
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Chromosomal abnormalities and Y chromosome microdeletions in infertile men with azoospermia and oligozoospermia in Eastern China [PDF]
Journal of International Medical Research, 2020 Objective The objective was to investigate the frequency and type of chromosomal abnormalities and Y chromosome microdeletions in infertile men with azoospermia and oligozoospermia to ensure appropriate genetic counseling before assisted reproduction in ...
Jing Sha +5 more
doaj +2 more sources
Genetic Insights into Azoospermia and Severe Oligozoospermia: Discovering Seven SNPs through GWAS and In Silico Analysis [PDF]
Current Issues in Molecular BiologyAzoospermia and severe oligozoospermia represent the most extreme forms of male infertility. Despite their prevalence, the genetic foundations of these conditions are not well understood, with only a limited number of genetic factors identified so far ...
Alexia Chatziparasidou +4 more
doaj +2 more sources
Association between methylenetetrahydrofolate reductase C677T polymorphisms and male oligozoospermia, asthenozoospermia or oligoasthenozoospermia: a case–control study [PDF]
Scientific ReportsMutation of methylenetetrahydrofolate reductase (MTHFR) C677T leads to the decrease of folate utilization and the impairment of spermatogenesis. This study attempts to investigate the association between MTHFR C677T polymorphisms and nonobstructive ...
Fu-jia Ren +2 more
doaj +2 more sources
Novel biallelic HFM1 variants cause severe oligozoospermia with favorable intracytoplasmic sperm injection outcome [PDF]
Asian Journal of AndrologyMale factors contribute to 50% of infertility cases, with 20%–30% of cases being solely attributed to male infertility. Helicase for meiosis 1 (HFM1) plays a crucial role in ensuring proper crossover formation and synapsis of homologous chromosomes ...
Liu Liu +7 more
doaj +2 more sources
Conception in Spite of Extreme Oligozoospermia [PDF]
BMJ, 1951 M M, WHITE, M, BARTON
openaire +4 more sources
Study the Association Between CPEB2 Gene Polymorphism with the Risk of Idiopathic Azoospermia/Severe Oligozoospermia of Men [PDF]
Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2018 Background and Aim: The CPEB gene encodes an important protein, which play critical roles in translational regulation of oogenesis and spermatogenesis procedures.
Reza Kian Bostanabad, Saeid Ghorbian
doaj +1 more source
Methylation Status Of MTHFR Promoter And Oligozoospermia Risk: An Epigenetic Study And In Silico Analysis [PDF]
Cell Journal, 2021 Objective: In this study, we evaluated the effects of promoter methylation of MTHFR on oligozoospermia risk, followed by an in silico analysis. Materials and Methods: In a case-control study, semen samples were collected from infertile and healthy ...
Atefeh Rezaeian +2 more
doaj +1 more source
From azoospermia to macrozoospermia, a phenotypic continuum due to mutations in the ZMYND15 gene
Asian Journal of Andrology, 2022 Thanks to tremendous advances in sequencing technologies and in particular to whole exome sequencing (WES), many genes have now been linked to severe sperm defects.
Zine-Eddine Kherraf +7 more
doaj +1 more source
Evaluation of five candidate genes from GWAS for association with oligozoospermia in a Han Chinese population. [PDF]
PLoS ONE, 2013 BACKGROUND: Oligozoospermia is one of the severe forms of idiopathic male infertility. However, its pathology is largely unknown, and few genetic factors have been defined.
Miaofei Xu +13 more
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