Results 11 to 20 of about 8,465 (222)

Tyrosol effectively improves spermatogenesis recovery by S100A9/TLR4/NF-κB pathway in busulfan-induced oligozoospermia mice [PDF]

PeerJ
Background Oligozoospermia is a prevalent clinical manifestation of male infertility. It has been provided to be bound up with testicular inflammation and oxidative stress.
Weizhen Wang, Wenbiao Zhou, Xiaoran Li, Taowen Ye, Wanqing Zhu, Guanning Zhong, Chengniu Wang, Haiying Geng, Xiaofang Tan, RuiKun Hu, Xiaorong Wang   +10 more
doaj   +3 more sources

Novel biallelic HFM1 variants cause severe oligozoospermia with favorable intracytoplasmic sperm injection outcome [PDF]

Asian Journal of Andrology
Male factors contribute to 50% of infertility cases, with 20%–30% of cases being solely attributed to male infertility. Helicase for meiosis 1 (HFM1) plays a crucial role in ensuring proper crossover formation and synapsis of homologous chromosomes ...
Liu Liu, Yi-Ling Zhou, Wei-Dong Tian, Feng Jiang, Jia-Xiong Wang, Feng Zhang, Chun-Yu Liu, Hong Zhu   +7 more
doaj   +2 more sources

Association between methylenetetrahydrofolate reductase C677T polymorphisms and male oligozoospermia, asthenozoospermia or oligoasthenozoospermia: a case–control study [PDF]

Scientific Reports
Mutation of methylenetetrahydrofolate reductase (MTHFR) C677T leads to the decrease of folate utilization and the impairment of spermatogenesis. This study attempts to investigate the association between MTHFR C677T polymorphisms and nonobstructive ...
Fu-jia Ren, Guo-ying Fang, Zhi-yong Zhang   +2 more
doaj   +2 more sources

Chromosomal abnormalities and Y chromosome microdeletions in infertile men with azoospermia and oligozoospermia in Eastern China

Journal of International Medical Research, 2020
Objective The objective was to investigate the frequency and type of chromosomal abnormalities and Y chromosome microdeletions in infertile men with azoospermia and oligozoospermia to ensure appropriate genetic counseling before assisted reproduction in ...
Jing Sha, Guiping Huang, Bei Zhang, Xia Wang, Zaochun Xu, Jingfang Zhai   +5 more
doaj   +1 more source

Homozygous mutation in the prokineticin-receptor2 gene (Val274Asp) presenting as reversible Kallmann syndrome and persistent oligozoospermia: case report. [PDF]

, 2008
Prokineticin 2 (Prok2) or prokineticin-receptor2 (Prok-R2) gene mutations are associated with Kallmann syndrome (KS). We describe a new homozygous mutation of Prok-R2 gene in a man displaying KS with an apparent reversal of hypogonadism.
Asci R, Bellastella A, Bellastella G, De Bellis A, ELEFANTE, ANDREA, Esposito D, IOLASCON, ACHILLE, Maione L, Sinisi AA   +8 more
core   +1 more source

Fertility of rats with artificial oligozoospermia [PDF]

Reproduction, 1980
Summary. Three different methods to obtain "oligospermic" rats were investigated. (1) Surgical reduction of the amount of tubular tissue diminished the number of spermatozoa present in the epididymis, but the animals were not infertile as long as they were able to ejaculate (32/33 rats). (2) Treatment with oestradiol benzoate on the 5th day after birth
J H, Aafjes, J M, Vels, E, Schenck
openaire   +2 more sources

Approach to the Patient With Oligozoospermia [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2013
Male infertility affects 1 in 20 men and is the sole or contributory factor in half of assisted reproductive treatments (ARTs). A reduced sperm density (oligozoospermia) is often accompanied by poor motility and morphology reflecting qualitative and quantitative defects in spermatogenesis.
openaire   +2 more sources

Sperm transcriptome profiling in oligozoospermia [PDF]

Journal of Assisted Reproduction and Genetics, 2011
Investigate in what extent sperm transcriptome of infertile men is different from that of fertile individuals.Semen samples were collected for determination of sperm parameters as well as for RNA isolation. Gene expression profile was investigated in spermatozoa of 8 infertile and 3 fertile men by microarray analysis using the Affymetrix Chip HG-U133 ...
Debbie, Montjean, Pierre, De La Grange, David, Gentien, Audrey, Rapinat, Stéphanie, Belloc, Paul, Cohen-Bacrie, Yves, Menezo, Moncef, Benkhalifa   +7 more
openaire   +2 more sources

Serum inhibin B as a marker of spermatogenesis [PDF]

, 1998
Inhibin B is produced by Sertoli cells, provides negative feedback on FSH secretion, and may prove to be an important marker for the functioning of seminiferous tubules.
Jong, F.H. (Frank) de, Pierik, F.H. (Frank), Stijnen, Th. (Theo), Vreeburg, J.T.M. (Jan), Weber, R.F.A. (Robert)   +4 more
core   +4 more sources

Perturbation of genomic imprinting in oligozoospermia [PDF]

Epigenetics, 2009
The role of epigenetic modifications in oligozoospermia and other disorders of spermatogenesis remains poorly understood. While a variety of environmental, nutritional and genetic abnormalities can cause oligozoospermia, a condition associated with infertility, it is unclear whether chromatin modifications might be also involved in impaired ...
Filipponi, D., Feil, Robert
openaire   +3 more sources