Tyrosol effectively improves spermatogenesis recovery by S100A9/TLR4/NF-κB pathway in busulfan-induced oligozoospermia mice [PDF]
PeerJBackground Oligozoospermia is a prevalent clinical manifestation of male infertility. It has been provided to be bound up with testicular inflammation and oxidative stress.
Weizhen Wang +10 more
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Novel biallelic HFM1 variants cause severe oligozoospermia with favorable intracytoplasmic sperm injection outcome [PDF]
Asian Journal of AndrologyMale factors contribute to 50% of infertility cases, with 20%–30% of cases being solely attributed to male infertility. Helicase for meiosis 1 (HFM1) plays a crucial role in ensuring proper crossover formation and synapsis of homologous chromosomes ...
Liu Liu +7 more
doaj +2 more sources
Association between methylenetetrahydrofolate reductase C677T polymorphisms and male oligozoospermia, asthenozoospermia or oligoasthenozoospermia: a case–control study [PDF]
Scientific ReportsMutation of methylenetetrahydrofolate reductase (MTHFR) C677T leads to the decrease of folate utilization and the impairment of spermatogenesis. This study attempts to investigate the association between MTHFR C677T polymorphisms and nonobstructive ...
Fu-jia Ren +2 more
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Methylation Status Of MTHFR Promoter And Oligozoospermia Risk: An Epigenetic Study And In Silico Analysis [PDF]
Cell Journal, 2021 Objective: In this study, we evaluated the effects of promoter methylation of MTHFR on oligozoospermia risk, followed by an in silico analysis. Materials and Methods: In a case-control study, semen samples were collected from infertile and healthy ...
Atefeh Rezaeian +2 more
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Interleukin 17 and Growth Differentiation Factor 9 Influence in a Sample of Iraqi Infertile Males [PDF]
Archives of Razi Institute, 2023 Infertility is defined as the inability of couples to conceive after 1 year of regular unprotected intercourse, which affects 10-15% of couples. The present study aimed to investigate the influence of Interleukin-17 (IL-17) and growth differentiation ...
D. S Al-Rubaye +2 more
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From azoospermia to macrozoospermia, a phenotypic continuum due to mutations in the ZMYND15 gene
Asian Journal of Andrology, 2022 Thanks to tremendous advances in sequencing technologies and in particular to whole exome sequencing (WES), many genes have now been linked to severe sperm defects.
Zine-Eddine Kherraf +7 more
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Taiwanese Journal of Obstetrics & Gynecology, 2022 Objective: We present our study about the significance of karyotyping and azoospermia factor(AZF) analysis in patients with azoospermia or oligozoospermia.
Shin-Wen Chen +4 more
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Evaluation of five candidate genes from GWAS for association with oligozoospermia in a Han Chinese population. [PDF]
PLoS ONE, 2013 BACKGROUND: Oligozoospermia is one of the severe forms of idiopathic male infertility. However, its pathology is largely unknown, and few genetic factors have been defined.
Miaofei Xu +13 more
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Assessment of Thyroid Functions and its Relationship With Semen Quality in Men [PDF]
International Journal of Basic Science in Medicine, 2023 Introduction: In recent years, a partial relationship has been discovered between thyroid hormones and the formation of germ cells and the process of spermatogenesis.
Luay Qasim Abdulhameed
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Heliyon, 2022 The contribution of pyridoxine on various human disorders has been revealed in so many studies; however, this contribution on poor semen quality has yet to be investigated.
Saleem A. Banihani, Shefa’ M. Aljabali
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