Methylation Status of Imprinted Genes and Repetitive Elements in Sperm DNA from Infertile Males [PDF]
Stochastic, environmentally and/or genetically induced disturbances in the genome-wide epigenetic reprogramming processes during male germ-cell development may contribute to male infertility.
El Hajj, N. +7 more
core +1 more source
Introduction: Human spermatogenesis is a highly intricate process that requires the input of thousands of testis-specific genes. Defects in any of them at any stage of the process can have detrimental effects on sperm production and/or viability.
Sidra Qureshi +18 more
doaj +1 more source
Perturbation of genomic imprinting in oligozoospermia [PDF]
The role of epigenetic modifications in oligozoospermia and other disorders of spermatogenesis remains poorly understood. While a variety of environmental, nutritional and genetic abnormalities can cause oligozoospermia, a condition associated with infertility, it is unclear whether chromatin modifications might be also involved in impaired ...
Filipponi, D., Feil, Robert
openaire +3 more sources
The Effect of Recombinant Human Follicle-Stimulating Hormone on Sperm Quality, Chromatin Status and Clinical Outcomes of Infertile Oligozoospermic Men Candidate for Intracytoplasmic Sperm Injection: A Randomized Clinical Trial [PDF]
Background: Follicle-stimulating hormone (FSH) plays a crucial role in spermatogenesis; in this study, we assessed the effect of recombinant human FSH (rhFSH) on sperm parameters, chromatin status and clinical outcomes of infertile oligozoospermic men ...
Atefeh Verdi +3 more
doaj +1 more source
Study on occurrence of the IVS8-5T allele of the CFTR gene in Ukrainian males with spermatogenesis failure [PDF]
Aim. To study the IVS8-5T allele of the CFTR gene and it is involvement in spermatogenesis failure in men with azoospermia and oligozoospermia. Methods.
Fesai O. A. +3 more
core +1 more source
Decreased Sperm Motility Retarded ICSI Fertilization Rate in Severe Oligozoospermia but Good-Quality Embryo Transfer Had Achieved the Prospective Clinical Outcomes. [PDF]
INTRODUCTION:Spermatozoa motility is the critical parameter to affect the treatment outcomes during assisted reproductive technologies (ART), but its reproductive capability remains a little informed in condition of severe male factor infertility.
Jufeng Zheng +7 more
doaj +1 more source
Testicular histopathology, semen analysis and FSH, predictive value of sperm retrieval: supportive counseling in case of reoperation after testicular sperm extraction (TESE) [PDF]
Background: To provide indicators for the likelihood of sperm retrieval in patients undergoing testicular sperm extraction is a major issue in the management of male infertility by TESE.
Basciani, S +10 more
core +1 more source
Fertility of rats with artificial oligozoospermia [PDF]
Three different methods to obtain "oligospermic" rats were investigated. (1) Surgical reduction of the amount of tubular tissue diminished the number of spermatozoa present in the epididymis, but the animals were not infertile as long as they were able to ejaculate (32/33 rats).
J H, Aafjes, J M, Vels, E, Schenck
openaire +2 more sources
Relationship between Dairy Product Consumption and Oligospermia; a Case-Control Study
Introduction: Infertility affects an estimated 15% of couples globally and in Iran, a quarter of Introduction: One of the current debates regarding men’s reproductive health is the declining sperm count and the role of nutritional and environmental ...
Alireza Dizavi +4 more
doaj +1 more source
Genetic and epigenetic factors: Role in male infertility
Genetic factors contribute upto 15%-30% cases of male infertility. Formation of spermatozoa occurs in a sequential manner with mitotic, meiotic, and postmeiotic differentiation phases each of which is controlled by an intricate genetic program.
M B Shamsi, K Kumar, R Dada
doaj +1 more source

