Results 41 to 50 of about 8,359 (251)
Mechanisms of oligozoospermia: an oxidative stress perspective [PDF]
Infertile patients presenting with poor semen concentration, motility, and morphology have significantly higher levels of reactive oxygen species (ROS). In this cross-sectional study, our goal was to: 1) determine how semen parameters such as concentration, motility, morphology, as well as ROS are altered in oligozoospermic men alone and those in ...
Ashok Agarwal+3 more
openaire +3 more sources
Mutations involving the SRY-related gene SOX8 are associated with a spectrum of human reproductive anomalies [PDF]
SOX8 is an HMG-box transcription factor closely related to SRY and SOX9. Deletion of the gene encoding Sox8 in mice causes reproductive dysfunction but the role of SOX8 in humans is unknown.
Achermann, JC+37 more
core +11 more sources
Methylation Status of Imprinted Genes and Repetitive Elements in Sperm DNA from Infertile Males [PDF]
Stochastic, environmentally and/or genetically induced disturbances in the genome-wide epigenetic reprogramming processes during male germ-cell development may contribute to male infertility.
El Hajj, N.+7 more
core +1 more source
The contribution of pyridoxine on various human disorders has been revealed in so many studies; however, this contribution on poor semen quality has yet to be investigated.
Saleem A. Banihani, Shefa’ M. Aljabali
doaj
PURPOSE: To determine the frequency of genetic alterations in a population of Brazilian infertile men with severe oligozoospermia or non-obstructive azoospermia.
Fernanda A. Mafra+6 more
doaj +1 more source
A large proportion of patients with idiopathic spermatogenic failure (SPGF; oligozoospermia or nonobstructive azoospermia [NOA]) do not receive a diagnosis despite an extensive diagnostic workup.
Rossella Cannarella+7 more
doaj +1 more source
Testicular Biopsy in Azoospermia and Severe Oligozoospermia [PDF]
The continued experience of testicular biopsy application in 861 cases of azoospermia and 152 cases of severe oligospermia is reported adding to the previously published cases of 1075 patients with azoospermia. The most common finding in the whole series was that of normal testis denoting obstruction (48%), while among cases of functional azoospermia ...
S. M. Girgis+4 more
openaire +3 more sources
Genetic and epigenetic factors: Role in male infertility
Genetic factors contribute upto 15%-30% cases of male infertility. Formation of spermatozoa occurs in a sequential manner with mitotic, meiotic, and postmeiotic differentiation phases each of which is controlled by an intricate genetic program.
M B Shamsi, K Kumar, R Dada
doaj +1 more source
Factors associated with aberrant imprint methylation and oligozoospermia [PDF]
AbstractDisturbingly, the number of patients with oligozoospermia (low sperm count) has been gradually increasing in industrialized countries. Epigenetic alterations are believed to be involved in this condition. Recent studies have clarified that intrinsic and extrinsic factors can induce epigenetic transgenerational phenotypes through apparent ...
Nobuo Yaegashi+10 more
openaire +3 more sources
Biochemistry and functional aspects of human glandular kallikreins [PDF]
Human urinary kallikrein was purified by gel filtration on Sephacryl S-200 and affinity chromatography on aprotinin-Sepharose, followed by ion exchange chromatography on DEAE-Sepharose.
B. Schütte+24 more
core +1 more source