Results 61 to 70 of about 8,465 (222)
ABSTRACT Background Testicular germ cell tumours (TGCT) are the most common malignancies among young men and represent a major threat to reproductive health. Both the disease itself and oncological treatments, particularly chemotherapy, can compromise spermatogenesis and semen quality.
Ondrej Sanovec +18 more
wiley +1 more source
Testicular Biopsy in Azoospermia and Severe Oligozoospermia [PDF]
The continued experience of testicular biopsy application in 861 cases of azoospermia and 152 cases of severe oligospermia is reported adding to the previously published cases of 1075 patients with azoospermia. The most common finding in the whole series was that of normal testis denoting obstruction (48%), while among cases of functional azoospermia ...
M N, Momen +4 more
openaire +2 more sources
Evaluation of Serial Thawing-Refreezing on Human Spermatozoa Resistance Using Cryovials and Straws [PDF]
Background: We designed this study to detect the cryoinjury rate on human sperm after serial freezing and thawing, taking into consideration the effects of using cryovials and straws.
Fatemeh Ghasemian +3 more
doaj
Pesquisa de microdeleções AZF em homens inférteis na população portuguesa [PDF]
A infertilidade conjugal, definida como a incapacidade de conceção de um casal ao fim de um ano de relações sexuais desprotegidas, afeta 10 a 15% dos casais em idade reprodutiva, sendo que as causas masculinas constituem 30 a 40% das causas de ...
Aguiar, Ana +8 more
core
ABSTRACT Background Klinefelter syndrome (KS) is characterized by marked phenotypic heterogeneity that might be influenced by genetic modifiers, including androgen receptor (AR) repeat length (CAGn and GGCn). The clinical relevance of these repeat lengths in patients with KS before testosterone replacement therapy (TRT) remains unclear.
Andrea Graziani +8 more
wiley +1 more source
Chromosomal disorders and male infertility [PDF]
Infertility in humans is surprisingly common occurring in approximately 15% of the population wishing to start a family. Despite this, the molecular and genetic factors underlying the cause of infertility remain largely undiscovered.
Harton, Gary L. +1 more
core +1 more source
ABSTRACT Background Genetic variability within the follicle‐stimulating hormone (FSH)‐related genes might contribute to phenotypic heterogeneity in patients with Klinefelter syndrome (KS), yet its clinical impact on sperm retrieval remains unclear. Objectives To investigate the association between FSHB c.211 G > T and FSHR polymorphisms (c.2039 A > G ...
Andrea Graziani +6 more
wiley +1 more source
A large proportion of patients with idiopathic spermatogenic failure (SPGF; oligozoospermia or nonobstructive azoospermia [NOA]) do not receive a diagnosis despite an extensive diagnostic workup.
Rossella Cannarella +7 more
doaj +1 more source
AZF-deletion – one of the genetic causes of male infertility [PDF]
Можливості дослідження причин безпліддя у чоловіків значно розширилися завдяки розшифровці генома людини, секвенуванню Y-хромосоми і впровадженню сучасних молекулярних технологій в медичну практику.
Padalko, L.I., Polion, M.Y., Stus, V.P.
core
Diagnostic yield of OCT3/4 reflex testing in testicular biopsy
GCNIS detection frequency was 48/3353 (1.4%) testicular biopsies from 42/1870 (2.2%) men who underwent testicular biopsy with or without testicular sperm extraction (TESE). OCT3/4 was particularly helpful for detecting interstitial seminoma, GCNIS coexisting with mature spermatogenesis, and focal GCNIS.
Roselyne Choiniere +2 more
wiley +1 more source

