Luteinizing hormone receptor knockout mouse: What has it taught us?
Andrology, EarlyView.Abstract Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis ...
Ilpo T. Huhtaniemi
wiley +1 more source
CAG repeats polymorphism of androgen receptor gene, Kennedy’s disease and male infertility
Андрология и генитальная хирургия, 2019 Genetic factors are a common cause of severe pathozoospermia and male infertility. An increase in the length of trinucleotide repeats causes a number of progressive neurodegenerative diseases, including spinal bulbar muscular atrophy — Kennedy syndrome ...
L. P. Melikyan, V. B. Chernykh
doaj +1 more source
The role of iron in normal and impaired testicular function
Andrology, EarlyView.Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer +2 more
wiley +1 more source
Genetic causes of nonsyndromic forms of azoospermia and severe oligozoospermia in infertility men
Андрология и генитальная хирургия, 2019 Spermatogenesis is a complex biological process of male germ cells differentiation and maturation involving more than 2300 genes in the human. Until recently, only a small part of them was investigated in severe pathozoospermia and male infertility ...
O. A. Solovova, V. B. Chernykh
doaj +1 more source
Pesquisa de microdeleções AZF em homens inférteis na população portuguesa [PDF]
, 2014 A infertilidade conjugal, definida como a incapacidade de conceção de um casal ao fim de um ano de relações sexuais desprotegidas, afeta 10 a 15% dos casais em idade reprodutiva, sendo que as causas masculinas constituem 30 a 40% das causas de ...
Aguiar, Ana +8 more
core
Sperm Telomere Interactions Are Impaired in Testicular Cancer Before and After Adjuvant Therapy
Andrology, EarlyView.ABSTRACT Background No study has yet explored telomere length or interaction in sperm nuclei of testicular cancer (TC) patients exposed to chemotherapy or radiotherapy. However, sperm telomere dynamics have emerged as a potential marker in male infertility.
Benoit Berby +10 more
wiley +1 more source
Ekspresi Gen Family Bcl-2 dan Ekspresi Gen Protein Kanal Ion Vdac1 pada Oligozoospermia
Jurnal Kesehatan Andalas, 2014 AbstrakSalah satu bentuk infertilitas pada pria adalah jumlah spermatozoa yang kurang dari normal (Oligozoospermia). Berbagai mekanisme diduga berperan dalam terjadinya oligozoospermia, mulai dari faktor fisik, stress, makanan dan molekuler.
Arni Amir
doaj
Reproductive health aspects in men with idiopathic inflammatory myopathy: a multicenter study [PDF]
, 2009 OBJECTIVE: To evaluate reproductive health of males with idiopathic inflammatory myopathies (IIM), and comparing them with a control group. METHODS: Demographic data, urologic evaluation (including pubertal parameters and sexual/erectile function ...
Bonfá, Eloisa Silva Dutra de Oliveira +10 more
core +2 more sources
Semen Cryopreservation for Men Banking for Oligozoospermia, Cancers, and Other Conditions: 24 Years’ Experience of an Italian Bank [PDF]
, 2023 Sara Marchiani +10 more
openalex +1 more source
Andrology, EarlyView.ABSTRACT Background Asthenozoospermia is a significant contributing factor to male infertility. Accumulating evidence indicates that impaired sperm motility is closely linked to dysregulated microRNA expression during spermatogenesis. Seminal plasma exosomes are enriched with diverse microRNAs, which play pivotal roles in modulating sperm motility, the
Zhi‐Jian Zhu +8 more
wiley +1 more source