Results 81 to 90 of about 8,359 (251)

Gonadal function in males with WFS1 spectrum disorder (Wolfram syndrome)—A European cohort perspective

Andrology, EarlyView.
Abstract Background WFS1 spectrum disorder, also known as Wolfram syndrome (WS) is an ultra‐rare (<1:500,000; ORPHA: 3463) monogenic (OMIM #222300) progressive neuroendocrine and neurodegenerative disorder, characterised by early‐onset insulin‐dependent diabetes, optic atrophy, central diabetes insipidus and sensi‐neuronal deafness.
Julia Rohayem, Olivia Cunningham, Denise Williams, Joachim Wistuba, Liam McCarthy, Timothy G. Barrett, Renuka P. Dias   +6 more
wiley   +1 more source

Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report

BMC Pregnancy and Childbirth, 2022
Background Permanent progression of paternal age and development of reproductive medicine lead to increase in number of children conceived with assisted reproductive techniques (ART).
Lidiia Zhytnik, Maire Peters, Kadi Tilk, Tiia Reimand, Piret Ilisson, Tiina Kahre, Ülle Murumets, Aivar Ehrenberg, Eva-Liina Ustav, Neeme Tõnisson, Signe Mölder, Hindrek Teder, Kaarel Krjutškov, Andres Salumets   +13 more
doaj   +1 more source

Paternal ischemic heart disease and chance of successful pregnancy outcomes

Andrology, EarlyView.
Abstract Background Only approximately 30% of conceptions result in live births. Historically, research has predominantly focused on maternal factors impacting pregnancy success, despite the cause remaining unidentified in most cases. The influence of paternal factors on a couple's likelihood of achieving a successful pregnancy is still not well ...
Anne‐Sofie Sønnichsen‐Dreehsen, Caroline Theilgaard Thorarinsson, Bente Mertz Nørgård, Jens Fedder, Mette Wod   +4 more
wiley   +1 more source

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

Combined Effects of the FSHR 2039 A/G and FSHR -29 G/A Polymorphisms on Male Reproductive Parameters

The World Journal of Men's Health, 2021
Purpose: The aim of this study was to evaluate the combined effect of FSHR 2039 A/G and FSHR -29 G/A single nucleotide polymorphisms (SNPs) on the male reproductive function in a cohort of Sicilian men.
Rossella Cannarella, Nicolò Musso, Rosita A. Condorelli, Marco Musmeci, Stefania Stefani, Sandro La Vignera, Aldo E. Calogero   +6 more
doaj   +1 more source

AZF-deletion – one of the genetic causes of male infertility [PDF]

, 2018
Можливості дослідження причин безпліддя у чоловіків значно розширилися завдяки розшифровці генома людини, секвенуванню Y-хромосоми і впровадженню сучасних молекулярних технологій в медичну практику.
Padalko, L.I., Polion, M.Y., Stus, V.P.
core  

Isodicentric Y Chromosomes and Sex Disorders as Byproducts of Homologous Recombination that Maintains Palindromes [PDF]

, 2009
Massive palindromes in the human Y chromosome harbor mirror-image gene pairs essential for spermatogenesis. During evolution, these gene pairs have been maintained by intrapalindrome, arm-to-arm recombination.
Brown, Laura G., Embry, Stephanie L., Korver, Cindy M., Lange, Julian, Oates, Robert D., Page, David C., Repping, Sjoerd, Silber, Sherman, Skaletsky, Helen, van Daalen, Saskia K.M.   +9 more
core   +1 more source

Adverse impact of acute Toxoplasma gondii infection on human spermatozoa

The FEBS Journal, EarlyView.
Toxoplasma gondii tachyzoites injected intraperitoneally crossed the blood‐testes barrier, appearing in testes/epididymis by day 6 post‐infection. In vitro exposure caused increased sperm necrosis/apoptosis and structural damage to heads/tails. Immunofluorescence and SEM revealed tachyzoites attaching to sperm tails, inducing twisting/detachment, and ...
Lisbeth Rojas‐Barón, Leandro Tana‐Hernandez, Mireille H. Nguele Ampama, Raúl Sanchéz, Ulrich Gärtner, Florian M. E. Wagenlehner, Christian Preußer, Elke Pogge von Strandmann, Carlos Hermosilla, Anja Taubert, María E. Francia, Zahady D. Velasquez   +11 more
wiley   +1 more source

Reproductive health aspects in men with idiopathic inflammatory myopathy: a multicenter study [PDF]

, 2009
OBJECTIVE: To evaluate reproductive health of males with idiopathic inflammatory myopathies (IIM), and comparing them with a control group. METHODS: Demographic data, urologic evaluation (including pubertal parameters and sexual/erectile function ...
Bonfá, Eloisa Silva Dutra de Oliveira, Borges, Claudia Tereza Lobato, Hallak, Jorge, Hilário, Maria Odete Esteves, Leal, Marta Miranda, Moraes, Ana Julia Pantoja, Ronchezel, Marcos, Saito, Osmar, Sallum, Adriana Maluf Elias, Silva, Clovis Artur Almeida da, Terreri, Maria Teresa Ramos Ascensão   +10 more
core   +2 more sources

How exome sequencing improves the diagnostics and management of men with non‐syndromic infertility

Andrology, Volume 13, Issue 5, Page 1011-1024, July 2025.
Abstract Male infertility affects approximately 17% of all men and represents a complex disorder in which not only semen parameters such as sperm motility, morphology, and number of sperm are highly variable, but also testicular phenotypes range from normal spermatogenesis to complete absence of germ cells.
Birgit Stallmeyer, Ann‐Kristin Dicke, Frank Tüttelmann   +2 more
wiley   +1 more source