Results 51 to 60 of about 2,876 (190)

A case of myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA)-associated glomerulonephritis and concurrent membranous nephropathy [PDF]

open access: yes, 2013
BACKGROUND: Myeloperoxidase anti-neutrophil cytoplasmic antibody-associated glomerulonephritis (MPO-ANCA-GN) and concurrent membranous nephropathy (MN) are very rare combination. Their causal relationship has been suggested, but not determined.
Hideaki Yamabe   +8 more
core   +1 more source

Co-Milling: A Successful Approach to Enhance Solubility of a Poorly Soluble Antihypertensive Drug [PDF]

open access: yes, 2023
The aim of the work was to enhance the solubilization of Olmesartan-medoxomil (OM) and formulate stable, rapidly-dissolving-tablet formulations. OM, on the other hand, is classified as Biopharmaceutics Classification System (BCS) Class II drug, which ...
Bayoumi, Asmaa Abdelaziz   +1 more
core   +2 more sources

Rational Design of Palladium and Platinum Chemosensors for Bio‐Applications

open access: yesAdvanced Sensor Research, Volume 4, Issue 2, February 2025.
Precious group 10 d‐block metals, particularly palladium, and platinum, are widely utilized in various industries. However, their widespread use comes at a cost with potentially adverse effects to human health and the environment. This review which surveys the chemosensing mechanism and practical applications of palladium and platinum sensor probes ...
Daniel Nnaemaka Tritton   +5 more
wiley   +1 more source

Synthesis and Physicochemical Characterization of the Process-Related Impurities of Olmesartan Medoxomil. Do 5-(Biphenyl-2-yl)-1-triphenylmethyltetrazole Intermediates in Sartan Syntheses Exist?

open access: yesMolecules, 2015
During the process development for multigram-scale synthesis of olmesartan medoxomil (OM), two principal regioisomeric process-related impurities were observed along with the final active pharmaceutical ingredient (API). The impurities were identified as
Iwona Dams   +7 more
doaj   +1 more source

The potential therapeutic use of renin-angiotensin system inhibitors in the treatment of inflammatory diseases [PDF]

open access: yes, 2019
Inflammation is a normal part of the immune response to injury or infection but its dysregulation promotes the development of inflammatory diseases, which cause considerable human suffering.
Avan, Amir   +5 more
core   +1 more source

Uptake and metabolization of four sartan drugs by eight different plants: Targeted and untargeted analyses by HPLC‐drift‐tube‐ion‐mobility quadrupole time‐of‐flight mass spectrometry

open access: yesELECTROPHORESIS, Volume 46, Issue 3-4, Page 135-142, February 2025.
Abstract In this study, we investigated the uptake and metabolization of four drugs (plus the associated prodrugs) from the sartan family by eight edible plants. Growing the plants hydroponically in a medium containing the respective drug, more than 40 phases I and II metabolites derived from the four sartan drugs could be tentatively identified.
Laura Zellner   +4 more
wiley   +1 more source

EVALUATION OF ANTIHYPERTENSIVE THERAPY WITH THE COMBINATION OF OLMESARTAN MEDOXOMIL AND HYDROCHLOROTHIAZIDE

open access: yesРоссийский кардиологический журнал, 2011
Most patients with hypertension require more than one agent to control blood pressure (BP). The purpose of this study was to assess the efficacy and safety of the angiotensin II receptor blocker olmesartan medoxomil in combination with ...
Steven G. Chrysant   +3 more
doaj  

Malabsorción inducida por fármacos. Revisión de los casos notificados al Sistema Español de Farmacovigilancia [PDF]

open access: yes, 2019
El objetivo de este trabajo es revisar los casos notificados al SEFV – H por problemas de malabsorción en relación con el consumo de fármacos y describir sus características.
Navajo Lozano, Francisco Javier
core  

Efficacy of Fixed-Dose Combination Therapy in the Treatment of Patients with Hypertension: Focus on Amlodipine/valsartan [PDF]

open access: yes, 2010
Early initiation of rational and effective combination therapy consisting of antihypertensive drugs with two different and complementary mechanisms of actions is increasingly becoming accepted in clinical practice and by guidelines as a first-line ...
Marques da Silva, P
core   +1 more source

Association between chronic diseases and severe periodontal disease progression: A retrospective cohort study in a city of Japan

open access: yesJournal of General and Family Medicine, Volume 26, Issue 1, Page 54-64, January 2025.
This manuscript is a study demonstrating the association between the progression of severe periodontal diseases and chronic diseases commonly addressed in primary care. We used claims data and defined the outcome as the “progression of severe periodontitis” and followed patients for 4 years.
Sayaka Nin   +8 more
wiley   +1 more source

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