Results 31 to 40 of about 2,876 (190)

A review of olmesartan medoxomil monotherapy: antihypertensive efficacy similar to that of other angiotensin II receptor blocker/hydrochlorothiazide combinations?

open access: yesКардиоваскулярная терапия и профилактика, 2011
Angiotensin II receptor blockers (ARBs) have been available in the United Statessince 1995. These agents have demonstrated antihypertensive efficacy at least similar to that of agents from other antihypertensive classes.
M. Greathouse
doaj   +1 more source

In silico assessment of chronic toxicity of a combination drug namely ‘Olmesartan medoxomil and Hydrochlorothiazide’, marketed in Bangladesh

open access: yesFuture Journal of Pharmaceutical Sciences, 2021
Background Nowadays combination therapy has become more popular due to their additional effect, synergistic effect and antagonistic effect. Any of these can influence the treatment profile.
Matrika Saha Roy   +8 more
doaj   +1 more source

Single-Pill Combination with Three Antihypertensive Agents to Improve Blood Pressure Control in Hypertension: Focus on Olmesartan-Based Combinations. [PDF]

open access: yes, 2023
Blood pressure control remains an unmet clinical need. Only about half of patients achieve their blood pressure (BP) targets and of these, the majority require combination and double or triple therapies. International guidelines recommend the association
Burnier, M., Redon, J., Volpe, M.
core   +1 more source

Linking FHIR‐Based Medication Data to a Computable Algorithm for Heart Medication Optimization: A Critical Component of Any Medication Learning Health System

open access: yesLearning Health Systems, Volume 10, Issue 1, January 2026.
ABSTRACT Introduction Despite strong evidence supporting guideline‐directed medical therapy (GDMT) for heart failure with reduced ejection fraction (HFrEF), a significant gap persists in the consistent application of these therapies. This shortfall has prompted organizations like the American College of Cardiology to recommend leveraging electronic ...
Joey LeGrand   +5 more
wiley   +1 more source

The use of nanotechnology in cardiovascular disease [PDF]

open access: yes, 2018
Cardiovascular diseases claim a number of lives globally; many of which are preventable. With the increase in diets that consist of high saturated fat, salt, and sugar, people often living sedentary lifestyles, and a rise in cases of obesity, the ...
Chandarana, M, Curtis, A, Hoskins, C
core   +3 more sources

Repurposing Acebutolol for Osteoporosis Treatment: Insights From Multi‐Omics and Multi‐Modal Data Analysis

open access: yesClinical Pharmacology &Therapeutics, Volume 118, Issue 6, Page 1463-1476, December 2025.
Overview of a multi‐omics based drug repurposing strategy. The systematic drug repurposing strategy included the following steps: (1) osteoporosis driver signaling networks were identified from multi‐omics data; (2) drug functional modules were obtained using a network fusion approach to integrate drug similarity information; (3) all drugs were ranked ...
Dan‐Yang Liu   +21 more
wiley   +1 more source

Looking for an optimal antihypertensive combination. Focus on azilsartan medoxomil/chlorthalidone

open access: yesРоссийский кардиологический журнал
The article analyzes data from clinical studies on the efficacy and safety of azilsartan medoxomil/chlorthalidone combination and its components. According to the analyzed sources, both individual components and their combination have proven their ...
M. D. Smirnova   +2 more
doaj   +1 more source

Stability-indicating comparative methods using mekc and lc for determination of olmesartan medoxomil

open access: yesQuímica Nova, 2013
A stability-indicating method using MEKC was validated for the analysis of olmesartan medoxomil in tablets. Successful separation was achieved using a fused silica capillary (40 cm x 50 µm i.d.); background electrolyte consisted of a combination of 10 ...
Lisiane Bajerski   +8 more
doaj   +3 more sources

Epidemiology and Management of Hypertension in the Hispanic Population [PDF]

open access: yes, 2012
Hispanics are the fastest growing ethnic minority in the USA. Among Hispanics, lack of hypertension awareness and lack of effective blood pressure (BP) control are problematic, as are higher incidence rates of hypertension-related co-morbidities compared
Nicolas J. Guzman
core   +1 more source

Pseudo‐Hypoaldosteronism Type 2 due to New Variants of KLHL3 Gene Diagnosed in an Adult Woman With Very High Sensitivity to Hydrochlorothiazide

open access: yesClinical Case Reports, Volume 13, Issue 9, September 2025.
ABSTRACT We report a case of pseudo‐hypoaldosteronism type 2 (PHA II) in a hypertensive 55‐year‐old woman who carried new variants of the KLHL3 gene. Hypersensitivity to hydrochlorothiazide was noted. Low dosages of hydrochlorothiazide were needed to restore potassium levels.
Massimo Giusti   +2 more
wiley   +1 more source

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