Efficacy and safety of olmesartan medoxomil-amlodipine besylate tablet in Chinese patients with essential hypertension: A prospective, single-arm, multi-center, real-world study. [PDF]
Abstract There lacks real‐world study with a large sample size assessing olmesartan medoxomil‐amlodipine besylate (OM‐AML) tablet. Therefore, this study aimed to evaluate the efficacy and safety of OM‐AML tablet in patients with essential hypertension.
Cui Z +39 more
europepmc +2 more sources
Is early and fast blood pressure control important in hypertension management? [PDF]
Control of blood pressure (BP) in hypertension is recognized as a key measure in the management of cardiovascular (CV) risk and is a cornerstone of preventive strategies. It is not defined, however, whether an initiation of the antihypertensive treatment
Gallo, Giovanna +2 more
core +1 more source
Unemployment and initiation of psychotropic medication:a case-crossover study of 2,348,552 Norwegian employees [PDF]
Objectives: The study investigated initiation of psychotropic medication in relation to unemployment in the months before, during and after job loss to detect the period of greatest risk.Methods: The Norwegian working population in 2004 (N=2 348 552) was
Bjorngaard, Johan Hakon +4 more
core +3 more sources
Background. For patients with hypertension, effective 24-hour blood pressure (BP) control is vital to ensure protection against the early morning surge in BP and the associated increased risk of cardiovascular events.
Hans R. Brunner, Kikuo Arakawa
doaj +1 more source
Fixed combinations in the management of hypertension: Patient perspectives and rationale for development and utility of the olmesartan – amlodipine combination [PDF]
Although the awareness and control of hypertension has increased, only 37% of hypertensive patients in the US achieve the conservative goal ...
Pimenta, Eduardo, Oparil, Suzanne
core +2 more sources
Olmesartan medoxomil (1) is the latest angiotensin receptor antagonist approved by the FDA for the treatment of hypertension. During the process development of olmesartan medoxomil, three process-related impurities were observed along with the final API.
G. Venkanna +5 more
doaj +1 more source
Comparative effect of olmesartan and candesartan on lipid metabolism and renal function in patients with hypertension: a retrospective observational study [PDF]
Background Angiotensin II receptor blockers (ARBs), including olmesartan and candesartan, are widely used antihypertensive agents. Many clinical studies have demonstrated that ARBs have organ-protecting effects, e.g., cardioprotection ...
Yayoi Nishida +4 more
core +1 more source
Enhancement of Dissolution Rate of Olmesartan Medoxomil Using Urea as Carrier by Different Solid Dispersion Techniques [PDF]
The poor solubility of drug substances in water and their low dissolution rate in aqueous G.I.T fluid often leads to insufficient bioavailability. As per Biopharmaceutical Classification System (BCS), Olmesartan belongs to the class-II category having ...
Gomathi, M. (M), Sangameswaran, B. (B)
core +5 more sources
Preparation of Broad-Spectrum Polyclonal Antibody and Development of an Indirect Competitive-Enzyme Linked Immunosorbent Assay for Multi-Residue Detection of Biphenyl Tetrazolium Sartans in Antihypertensive Health Foods [PDF]
An indirect competitive-enzyme linked immunosorbent assay (ic-ELISA) was established to detect the multi-residue of biphenyl tetrazolium sartans in antihypertensive health foods. Candesartan was coupled with bovine serum albumin to obtain immunogen.
LIU Fengyin, SU Peiyun, LIN Haobiao, LIU Hui, CHEN Jiayi, LU Zicheng, MU Hongtao, LI Gongke
doaj +1 more source
Angiotensin II receptor blockers decreased blood glucose levels: a longitudinal survey using data from electronic medical records [PDF]
Background A beneficial effect on glucose metabolism is reported with angiotensin receptor blocker (ARB) treatment of hypertension. The effect on blood glucose level during the course of treatment with ARBs in clinical cases is uncertain.
Noboru Kitamura +3 more
core +1 more source

