Effects of α lipoic acid combined with olmesartan medoxomil on blood glucose and oxidation indicators in patients with diabetic nephropathy [PDF]
. Background:. Diabetic nephropathy (DN) is a common microvascular complication of diabetes, which poses a serious threat to the health and life of patients.
Shengfu Jiao, MB +4 more
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A novel nano-formulation of olmesartan medoxomil with improved delivery and efficacy in the treatment of indomethacin-induced duodenitis in rats [PDF]
There are few studies addressing duodenal inflammation. This study was designed to investigate the effects of a recently developed biotechnological product, a nano-formulation of olmesartan medoxomil (OM) - olmesartan medoxomil zeinmersomes (OMZ) - for ...
H.A. Murad, T.M. Alqurashi
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Synthesis and Characterization of Process-Related Impurities of Antihypertensive Drug Olmesartan Medoxomil [PDF]
Olmesartan medoxomil (1) is the latest angiotensin receptor antagonist approved by the FDA for the treatment of hypertension. During the process development of olmesartan medoxomil, three process-related impurities were observed along with the final API.
G. Venkanna +5 more
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Investigation of hydrolysis of olmesartan medoxomil in different pH buffers by simultaneously measuring olmesartan medoxomil and olmesartan. [PDF]
Olmesartan medoxomil (OLM) is an ester prodrug of olmesartan (OL) developed to overcome the poor permeability of OL. OLM is an angiotensin receptor blocker and is commonly used to treat hypertension.
Lauren Landry, Xiaowei Dong
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Antihypertensive efficacy of olmesartan medoxomil and candesartan cilexetil in achieving 24-hour blood pressure reductions and ambulatory blood pressure goals [PDF]
Background. For patients with hypertension, effective 24-hour blood pressure (BP) control is vital to ensure protection against the early morning surge in BP and the associated increased risk of cardiovascular events.
Hans R. Brunner, Kikuo Arakawa
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Development and Validation of a Chromatography Method Using Tandem UV/Charged Aerosol Detector for Simultaneous Determination of Amlodipine Besylate and Olmesartan Medoxomil: Application to Drug-Excipient Compatibility Study [PDF]
A study was carried out to investigate compatibility of amlodipine besylate and olmesartan medoxomil with a variety of pharmaceutical excipients. Both drugs are antihypertensive agents that can be administered alone, in monotherapy, or in pharmaceutical ...
Ariadne M. Brondi +2 more
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Development of Transdermal Oleogel Containing Olmesartan Medoxomil: Statistical Optimization and Pharmacological Evaluation [PDF]
Ibrahim Elsayed +2 more
exaly +2 more sources
Interaction and Compatibility Studies in the Development of Olmesartan Medoxomil and Hydrochlorothiazide Formulations under a Real Manufacturing Process [PDF]
Araya-Sibaja A M +2 more
exaly +2 more sources
Development and validation of stability-indicating RP-HPLC method for determination of Olmesartan medoxomile in pharmaceutical dosage form and identification, characterization of alkaline degradation impurity of Olmesartan medoxomile drug substance as well as drug product [PDF]
Olmesartan Medoxomil (OLME) belongs to a group of angiotensin II receptor blockers used as an antihypertensive agent and is currently being used for prevention of Hypertension.
Jain P.S., Chaudhari A.J., Surana S.J.
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Preparation of Broad-Spectrum Polyclonal Antibody and Development of an Indirect Competitive-Enzyme Linked Immunosorbent Assay for Multi-Residue Detection of Biphenyl Tetrazolium Sartans in Antihypertensive Health Foods [PDF]
An indirect competitive-enzyme linked immunosorbent assay (ic-ELISA) was established to detect the multi-residue of biphenyl tetrazolium sartans in antihypertensive health foods. Candesartan was coupled with bovine serum albumin to obtain immunogen.
LIU Fengyin, SU Peiyun, LIN Haobiao, LIU Hui, CHEN Jiayi, LU Zicheng, MU Hongtao, LI Gongke
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