Intraoperative angioedema induced by angiotensin II receptor blocker: a case report [PDF]
Patient Safety in Surgery, 2018 Background Angiotensin II receptor blockers are a class of antihypertensive agent that is developed to exclude the adverse effects of angiotensin converting enzyme inhibitors.
Ala”a Alhowary +3 more
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Labial adhesions due to vulvovaginal lichen planus suspected to be caused by angiotensin II receptor blocker [PDF]
IJU Case ReportsIntroduction Lichenoid drug eruption, induced by gold or cardiovascular drugs, is one of the causes of lichen planus, and vulvovaginal erosive lichen planus can cause labial adhesions.
Yugo Sawada +4 more
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Angiotensin Ii Receptor Blockers [PDF]
Baylor University Medical Center Proceedings, 2003 The ARBs have very similar clinical profiles. They do, however, have different pharmacokinetic profiles, which may lead to some differences in efficacy. The newer agents irbesartan, candesartan, telmisartan, and olmesartan have longer half-lives and durations of action than the older agents losartan and valsartan (5).
Amy, Barreras, Cheryle, Gurk-Turner
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Oxidative DNA damage in kidneys and heart of hypertensive mice is prevented by blocking angiotensin II and aldosterone receptors. [PDF]
PLoS ONE, 2014 INTRODUCTION: Recently, we could show that angiotensin II, the reactive peptide of the blood pressure-regulating renin-angiotensin-aldosterone-system, causes the formation of reactive oxygen species and DNA damage in kidneys and hearts of hypertensive ...
Susanne Brand +4 more
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Angiotensin II receptor pharmacology and AT1-receptor blockers [PDF]
Journal of Human Hypertension, 1999 Angiotensin II (Ang II) has diverse physiological actions leading, for example, to increases in extracellular volume, peripheral vascular resistance and blood pressure, and has also been implicated in the regulation of cell growth and differentiation.
O, Chung, T, Csikós, T, Unger
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Role of vascular smooth muscle PPARγ in regulating AT1 receptor signaling and angiotensin II-dependent hypertension. [PDF]
PLoS ONE, 2014 Peroxisome proliferator activated receptor γ (PPARγ) has been reported to play a protective role in the vasculature; however, the underlying mechanisms involved are not entirely known.
Maria Alicia Carrillo-Sepulveda +4 more
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Heliyon, 2023 Bisphenol-A (BPA) is a synthetic chemical compound broadly used in the plastic and epoxy resin industries with a considerable potential for food contamination. Literary reports have suggested that the altered renin-angiotensin system (RAS) is a mechanism
Ahmed A. Morsi +11 more
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Receptor Interactions of Angiotensin II and Angiotensin Receptor Blockers—Relevance to COVID-19 [PDF]
Biomolecules, 2021 Angiotensin II (Ang II) may contain a charge relay system (CRS) involving Tyr/His/carboxylate, which creates a tyrosinate anion for receptor activation. Energy calculations were carried out to determine the preferred geometry for the CRS in the presence and absence of the Arg guanidino group occupying position 2 of Ang II.
Graham J. Moore +6 more
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Comparison of First-Line Dual Combination Treatments in Hypertension: Real-World Evidence from Multinational Heterogeneous Cohorts. [PDF]
, 2020 Background and objectives: 2018 ESC/ESH Hypertension guideline recommends 2-drug combination as initial anti-hypertensive therapy. However, real-world evidence for effectiveness of recommended regimens remains limited.
Cho, Jaehyeong +10 more
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Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 Background Sacubitril/Valsartan has been highly efficacious in randomized trials of heart failure with reduced ejection fraction (HFrEF). However, the effectiveness of sacubitril/valsartan in older patients hospitalized for HFrEF in real‐world US ...
Stephen J. Greene +16 more
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