Results 11 to 20 of about 7,055,245 (153)

An alternative synthesis of Azilsartan: an angiotensin II receptor blocker [PDF]

Current Issues in Pharmacy and Medical Sciences, 2015
This paper provides a description of an alternative, novel and commercially viable process which has been developed for the preparation of Azilsartan, a pro-drug of Azilsartan medoxomil, an angiotensin II receptor blocker.
Garaga Srinivas, Misra Nimesh C., Reddy Ambati V. Raghava, Prabahar Koilpillai Joseph, Takshinamoorthy Chandiran, Sanasi Paul Douglas, Korupolu Raghubabu   +6 more
doaj   +4 more sources

Effect of angiotensin II receptor blocker on TGF-β1, MMP-1, and collagen type I and type III concentration in New Zealand rabbit urethral stricture model

Research and Reports in Urology, 2018
Safendra Siregar, Reni Farenia, Suwandi Sugandi, Rully M Roesli Urology Division, Department of Surgery, Hasan Sadikin Hospital Bandung, Faculty of Medicine Padjadjaran University, Bandung, Indonesia Introduction: Urethral stricture is a disease with a ...
Siregar S, Farenia R, Sugandi S, Roesli RM   +3 more
doaj   +1 more source

The vascular renin-angiotensin-aldosterone system [PDF]

, 2001
PhDThe renin-angiotensin-aldosterone system (RAAS) is one of the major regulators of blood pressure. The actions and generation of RAAS components at the tissue level are less well appreciated.
Xiao, Fang
core   +4 more sources

Signaling of angiotensin II-induced vascular protein synthesis in conduit and resistance arteries in vivo [PDF]

, 2004
<b>Background</b> From in vitro studies, it has become clear that several signaling cascades are involved in angiotensin II-induced cellular hypertrophy.
Martens Fabrice MAC, Fabrice MAC Martens, Touyz, R.M., Daigle, Christine, Martens, Fabrice, Touyz Rhian M, Dao Huy, Christine Daigle, Huy Hao Dao, Daphné Girardot, Rhian M Touyz, Moreau Pierre, Girardot, D., Daigle, C., Dao, H., Moreau, P., Girardot, Daphné, Martens, F.M.A.C., Dao, Huy, Daigle Christine, Moreau, Pierre, Girardot Daphné, Pierre Moreau, Touyz, Rhian   +23 more
core   +2 more sources

The β-blocker Nebivolol Is a GRK/β-arrestin Biased Agonist [PDF]

, 2013
Nebivolol, a third generation β-adrenoceptor (β-AR) antagonist (β-blocker), causes vasodilation by inducing nitric oxide (NO) production. The mechanism via which nebivolol induces NO production remains unknown, resulting in the genesis of much of the ...
Jackson, Edwin K., Blessing, CP, Tammy Liu, Liu, Tammy, Liu, T, Christopher P Blessing, Jackson Edwin K., Liu Tammy, Gul, R, Pulakat, Lakshmi, Pulakat, L, Murat Bastepe, Blessing, Christopher P., Edwin K Jackson, Catherine E Erickson, Rukhsana Gul, Bastepe Murat, Lakshmi Pulakat, Andresen Bradley T., Nguyen, J, Pulakat Lakshmi, Gul, Rukhsana, Andresen, Bradley T., Erickson, CE, Blessing Christopher P., Holowka, David, Nguyen Jenny, Bastepe, Murat, Jackson, EK, Andresen, BT, Gul Rukhsana, Jenny Nguyen, Erickson Catherine E., Bastepe, M, Erickson, Catherine E., Nguyen, Jenny, Bradley T Andresen   +36 more
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Circumscribed ciliochoroidal effusion presenting as an acute angle closure attack

Journal of Ophthalmic & Vision Research, 2017
Purpose: To report a case of choroidal effusion probably caused by angiotensin receptor II blocker. Case Report: A 52-year-old man with aplastic anemia and high blood pressure who developed unilateral acute angle closure glaucoma after receiving oral ...
Roslyn Kathryn Manrique Lipa, María Eugenia González Sánchez, Carlos Antonio Hijar Ordovas, Abel Rojo Aragües, Carmen Garcia Borque   +4 more
doaj   +1 more source

Effect of long-term therapy with AT1angiotensin II receptor blockers in combination with aldosterone receptor inhibitor on ischemic myocardial remodelling and chronic heart failure

Медицинский совет, 2014
The article presents the results of a 6-month long-term therapy with angiotensin II receptor blocker Valsacor and aldosterone receptor blocker Spironolactone in patients with chronic heart failure (CHF) against a background of ischemic and/or post ...
AT Teplyakov, EV Grakova, AV Andrianova, EY Pushnikova, NV Protopopova, RS Karpov   +5 more
doaj   +1 more source

Adenoviral delivery of angiotensin-(1-7) or angiotensin-(1-9) inhibits cardiomyocyte hypertrophy via the mas or angiotensin Type 2 receptor [PDF]

, 2012
The counter-regulatory axis of the renin angiotensin system peptide angiotensin-(1-7) [Ang-(1-7)] has been identified as a potential therapeutic target in cardiac remodelling, acting via the mas receptor.
Nicklin Stuart A., Almalik Abdulaziz, Bruno M D C Godinho, Flores-Muñoz Monica, Flores-Muñoz, M., Almalik, A., Nicklin, S.A., Monica Flores-Muñoz, Stuart A Nicklin, Abdulaziz Almalik, Godinho, B.M.D.C., Godinho Bruno M. D. C.   +11 more
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Methylglyoxal Augments Angiotensin II–Induced Contraction in Rat Isolated Carotid Artery

Journal of Pharmacological Sciences, 2010
.: Methylglyoxal (MGO), a metabolite of glucose, accumulates in vascular tissues of a hypertensive animal. In the present study, we examined the effect of MGO on angiotensin (Ang) II–induced contraction of rat carotid artery.
Masashi Mukohda, Hideyuki Yamawaki, Muneyoshi Okada, Yukio Hara   +3 more
doaj   +1 more source

Intoxication with massive doses of amlodipine and candesartan requiring venoarterial extracorporeal membrane oxygenation

Acute Medicine & Surgery, 2023
Background Calcium channel blockers and angiotensin II receptor blockers are commonly prescribed to treat hypertension. Massive overdoses can cause both distributive and cardiogenic shock because of their effects on vascular smooth muscles and severe ...
Minagawa Yusuke, Yamana Hidetoshi, Tsutsumi Yusuke, Ishigami Koji, Togo Masahito, Yasuda Susumu, Ogura Takayuki   +6 more
doaj   +1 more source