Results 41 to 50 of about 964 (170)

Absence of Adverse Effects of Tiotropium/Olodaterol Compared with the Monocomponents on Long-Term Heart Rate and Blood Pressure in Patients with Moderate-to-Very-Severe COPD

open access: yesInternational Journal of COPD, 2020
Stefan Andreas,1,2 Lorcan McGarvey,3 Ulrich Bothner,4 Matthias Trampisch,4 Alberto de la Hoz,4 Matjaz Fležar,5 Roland Buhl,6 Peter Alter7 1Department of Cardiology and Pneumology, University Medical Center Göttingen, Göttingen, Germany ...
Andreas S   +7 more
doaj  

Errors associated with co‐names of medicines: The nomenclature of combination medicinal products

open access: yesBritish Journal of Clinical Pharmacology, Volume 90, Issue 11, Page 2705-2712, November 2024.
In comparison to the efforts required to bring a new drug or formulation to the clinic, bestowing a name on a medicine is relatively simple. However, if the name we choose causes confusion—by making its contents ambiguous or if it is too alike another drug—it can precipitate clinical errors.
Oisín N. Kavanagh   +2 more
wiley   +1 more source

COST-MINIMIZATION OF VILANTEROL / UMECLIDINIUM VERSUS OLODATEROL / TIOTROPIUM IN THE BASIC THERAPY OF SEVERE AND VERY SEVERE COPD

open access: yesФармакоэкономика, 2017
The recently introduced novel drug combinations for the treatment of COPD are based on long-acting beta-agonists (vilantererol / umeclidinum bromide) and long-acting anticholinergics (olodaterol / tiotropium bromide).
E. G. Kosolapov   +5 more
doaj   +1 more source

A severe tremor caused by a beta2 agonist in a patient with asthma‐chronic obstructive pulmonary disease overlap

open access: yesClinical Case Reports, Volume 12, Issue 8, August 2024.
Key Clinical Message A 46‐year‐old male developed respiratory distress due to asthma‐chronic obstructive pulmonary disease overlap and experienced severe tremor caused by beta2 agonist inhalant. We present our successful experience with tizanidine administration.
Kota Nakajima, Kenji Momo
wiley   +1 more source

Olodaterol attenuates citric acid-induced cough in naïve and ovalbumin-sensitized and challenged guinea pigs. [PDF]

open access: yesPLoS ONE, 2015
Excessive coughing is a common feature of airway diseases. Different G-protein coupled receptors, including β2-adrenergic receptors (β2-AR), have been implicated in the molecular mechanisms underlying the cough reflex.
Eva Wex, Thierry Bouyssou
doaj   +1 more source

Long-term safety of tiotropium/olodaterol Respimat® in patients with moderate-to-very severe COPD and renal impairment in the TONADO® studies

open access: yesInternational Journal of COPD, 2018
Craig LaForce,1 Eric Derom,2 Ulrich Bothner,3 Isabel M Kloer,3 Matthias Trampisch,4 Roland Buhl5 1NC Clinical Research, Raleigh, NC, USA; 2Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium; 3Pharmacovigilance, Boehringer ...
LaForce C   +5 more
doaj  

A perspective current and past modes of inhalation therapy

open access: yesMicrobial Biotechnology, Volume 17, Issue 2, February 2024.
Abstract Inhalation is the preferred route of delivery for anti‐asthma and chronic obstructive pulmonary disease (COPD) drugs. The use of this route has demonstrated efficacy in these and other conditions, it offers rapid onset of action, and is associated with minimal systemic exposure, thereby reducing the risk of adverse effects.
José Canto Mangana   +6 more
wiley   +1 more source

Efficacy of tiotropium–olodaterol fixed-dose combination in COPD

open access: yesInternational Journal of COPD, 2016
Eric Derom, Guy G Brusselle, Guy F Joos Department of Respiratory Medicine, Ghent University Hospital, Ghent, BelgiumAbstract: Tiotropium–olodaterol, formulated in the Respimat soft-mist inhaler, is an inhaled fixed-dose combination (FDC) of a long-
Derom E, Brusselle GG, Joos GF
doaj  

Prioritizing Asthma Treatment Drugs through Multicriteria Decision Making

open access: yesInternational Journal of Analytical Chemistry, Volume 2024, Issue 1, 2024.
Asthma is a medical condition characterized by inflammation, narrowing, and swelling of a person’s airways, leading to increased mucus production and difficulties in breathing. Topological indices are instrumental in assessing the physical and chemical attributes of these asthma drugs.
Sobia Sultana, Mahmood Ahmed
wiley   +1 more source

Lung function efficacy and symptomatic benefit of olodaterol once daily delivered via Respimat® versus placebo and formoterol twice daily in patients with GOLD 2–4 COPD: results from two replicate 48-week studies

open access: yesInternational Journal of COPD, 2014
Andrea Koch,1 Emilio Pizzichini,2 Alan Hamilton,3 Lorna Hart,3 Lawrence Korducki,4 Maria Cristina De Salvo,5 Pierluigi Paggiaro6 1Medical Clinic III for Pneumology, Allergology, Sleep and Respiratory Medicine, University Hospital Bochum-Bergmannsheil ...
Koch A   +6 more
doaj  

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