Results 1 to 10 of about 7,681 (214)

Alternative mechanisms for tiotropium

Pulmonary Pharmacology and Therapeutics, 2009
Tiotropium is commonly used in the treatment of chronic obstructive pulmonary disease. Although largely considered to be a long-acting bronchodilator, its demonstrated efficacy in reducing the frequency of exacerbations and preliminary evidence from ...
Eric D Bateman, Peter J Barnes, Nicholas J Gross   +2 more
exaly   +4 more sources

Tiotropium and exercise training in COPD patients: Effects on dyspnea and exercise tolerance [PDF]

International Journal of COPD, 2008
Nicolino Ambrosino1, Katia Foglio2, Gianni Balzano2, Pier Luigi Paggiaro1, Patrizia Lessi3, Steven Kesten3 On behalf of the Tiotropium Multicentric Italian Study Group1Cardio-Thoracic Department, University Hospital, Pisa, Italy; 2S Maugeri Foundation ...
Nicolino Ambrosino, Katia Foglio, Gianni Balzano, Pier Luigi Paggiaro, Patrizia Lessi, Steven Kesten   +5 more
doaj   +2 more sources

Tiotropium HandiHaler® and Respimat® in COPD: a pooled safety analysis [PDF]

International Journal of COPD, 2015
David MG Halpin,1 Ronald Dahl,2 Christoph Hallmann,3 Achim Mueller,3 Donald Tashkin4 1NHS SW, Royal Devon and Exeter Hospital, Exeter, Devon, England, UK; 2Allergy Centre, Odense University Hospital, Odense, Denmark; 3Boehringer Ingelheim Pharma GmbH ...
Halpin DMG, Dahl R, Hallmann C, Mueller A, Tashkin D   +4 more
doaj   +2 more sources

Comparison of tiotropium plus fluticasone propionate/salmeterol with tiotropium in COPD: A randomized controlled study

Respiratory Medicine, 2012
SummaryBackgroundThe combination of tiotropium and fluticasone propionate/salmeterol (FSC) is commonly used to treat chronic obstructive pulmonary disease (COPD), but no study had evaluated the effectiveness of tiotropium plus FSC with 250 μg of ...
Ki-Suck Jung, Hye Yun Park, Se Kyu Kim
exaly   +2 more sources

A randomized multicenter Phase II study of perioperative tiotropium intervention in gastric cancer patients with chronic obstructive pulmonary disease

International Journal of COPD, 2015
Sachio Fushida,1,2 Katsunobu Oyama,1,2 Masahide Kaji,2 Yasuo Hirono,2 Jun Kinoshita,1,2 Tomoya Tsukada,1,2 Hideaki Nezuka,2 Tatsuo Nakano,2 Masahiro Noto,2 Koji Nishijima,2 Takashi Fujimura,2 Tetsuo Ohta1,2 1Department of Gastroenterological Surgery ...
Fushida S, Oyama K, Kaji M, Hirono Y, Kinoshita J, Tsukada T, Nezuka H, Nakano T, Noto M, Nishijima K, Fujimura T, Ohta T   +11 more
doaj   +1 more source

Ten years of tiotropium: clinical impact and patient perspectives

International Journal of COPD, 2013
Abebaw M Yohannes,1 Martin J Connolly,2 Nicola A Hanania31Manchester Metropolitan University, Department of Health Professions, Manchester, UK; 2University of Auckland, Freemasons’ Department of Geriatric Medicine, Auckland, New Zealand ...
Yohannes AM, Connolly MJ, Hanania NA
doaj   +1 more source

Anti-inflammatory effects of tiotropium in COPD: a randomised double-blind trial [PDF]

ERJ Open Research
Background COPD is a major global health issue characterised by respiratory symptoms and exacerbations, significantly impacting mortality and quality of life.
Lisa H. van Smoorenburg, Tatiana Karp, Benedikt Ditz, Wouter H. van Geffen, Victor Guryev, Ali Almusa, Loes Kistemaker, Reinoud Gosens, Maarten van den Berge, Huib A.M. Kerstjens   +9 more
doaj   +2 more sources

Tiotropium: a new therapeutic option in asthma

Monaldi Archives for Chest Disease, 2013
Tiotropium: a new therapeutic option in asthma. F. Novelli, F. Costa, M. Latorre, L. Malagrinò, A. Celi, B. Vagaggini, P. Paggiaro. Although bronchial hyperresponsiveness to cholinergic agents is a main feature of asthma, the role of anticholinergic ...
F. Novelli, F. Costa, M. Latorre, L. Malagrinò, A. Celi, B. Vagaggini, P. Paggiaro   +6 more
doaj   +3 more sources

Bronchodilator response to formoterol after regular tiotropium or to tiotropium after regular formoterol in COPD patients

Respiratory Medicine, 2005
SummaryWe conducted a randomized, crossover trial with tiotropium 18μg once daily (group A), and formoterol 12μg twice daily (group B) over a 5-day period for each drug, with a 10-day washout, in 20 COPD patients.
Mario Cazzola, Paolo Noschese, Antonello Salzillo   +2 more
exaly   +2 more sources

Tiotropium inhibits methacholine-induced extracellular matrix production via β-catenin signaling in human airway smooth muscle cells

International Journal of COPD, 2018
Yating Huo, Lili Guan, Jiawen Xu, Luqian Zhou, Rongchang Chen State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China Background: Airway ...
Huo Y, Guan L, Xu J, Zhou L, Chen R
doaj   +1 more source