Effect of sulfonamide derivatives of phenylglycine on scopolamine‐induced amnesia in rats
Ibrain, 2023 Alzheimer's disease is a neurodegenerative disease responsible for dementia and other neuropsychiatric symptoms. In the present study, compounds 30 and 33, developed earlier in our laboratory as selective butyrylcholinesterase inhibitors, were tested ...
Ankit Ganeshpurkar +6 more
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Biomolecules, 2020 Oxidative stress-mediated neuroinflammatory events are the hallmark of neurodegenerative diseases. The current study aimed to synthesize a series of novel succinamide derivatives and to further investigate the neuroprotective potential of these compounds
Sumbal Iqbal +9 more
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Neuroprotective Potential of New Monoterpene-Adamatane Conjugates—A Pilot Study [PDF]
Current Issues in Molecular BiologyNeurodegenerative diseases, including Alzheimer’s disease, are marked by cholinergic dysfunction, oxidative stress, and reduced neurotrophic support, which drives the quest for multifunctional therapeutic agents.
Stela Dragomanova +18 more
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A Novel Probiotic Limosilactobacillus fermentum IOB802 and Its Postbiotic Alleviate Cognitive Impairment Induced by Scopolamine in Mice [PDF]
FoodsCognitive impairment is acknowledged as an early stage between normal aging and Alzheimer’s disease, emphasizing the need for prompt intervention. There is growing evidence that the gut–brain axis plays a role in regulating cognitive function, indicating
Yuxuan Song +9 more
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Bioorganic Chemistry, Toxinology, and Pharmaceutical Uses of Datura Metabolites and Derivatives [PDF]
ToxinsDatura species have been recognized for their potent pharmacological properties, producing a diverse array of tropane and non-tropane alkaloids with significant clinical and toxicological relevance.
Amin Mahmood Thawabteh +6 more
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Electroacupuncture Ameliorates Scopolamine-Induced Dry Eye Disease in Mice by Restoring Lacrimal Gland Lipid Homeostasis and Reducing IL-1β/IL-18 Expression [PDF]
Journal of Immunology ResearchDry eye disease (DED) can lead to severe eye discomfort, which manifests as dryness, pain and decreased vision, and significantly affects daily life.
Shangjie Liang +5 more
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Comparative neuroprotective and cognitive effects of human umbilical cord mesenchymal stem cells, secretome, and exosomes in a rat model of pilocarpine-induced epilepsy [PDF]
Veterinary WorldBackground and Aim: Epilepsy is a chronic neurological disorder characterized by recurrent seizures, neuronal degeneration, and cognitive impairment. Current antiepileptic therapies mainly control seizures and do not effectively prevent epileptogenesis ...
Sri Hastuti +4 more
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Antiamnestic effect of new nicotinic acid derivatives [PDF]
Research Results in Pharmacology, 2021 Introduction: The search for new drugs for the prevention and treatment of vascular cognitive disorders continues to be a relevant task of pharmacology.
Victor V. Yasnetsov +3 more
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Atropine and Scopolamine in Maize Products from the Retail Stores in the Republic of Serbia
Toxins, 2022 The cereal grains, which represent the cultivated grasses fruits, supply almost half of the total caloric requirements for humans and provide more nourishment compared with any other class of the food.
Gorica Vuković +11 more
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Thermal (In)stability of Atropine and Scopolamine in the GC-MS Inlet
Toxics, 2021 The intoxication due to unintentional or intentional ingestion of plant material containing tropane alkaloids is quite frequent. GC-MS method is still widely used for the identification of these toxicologically important substances in human specimen ...
Gordana Koželj, Helena Prosen
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