Results 21 to 30 of about 5,625 (178)
Tiotropium in children and adolescents with asthma [PDF]
Annals of Allergy, Asthma & Immunology, 2020 Asthma is a major cause of morbidity in children, despite the availability of various treatments. In adults, tiotropium-a long-acting muscarinic antagonist-as add-on therapy to an inhaled corticosteroid with or without a long-acting β2-agonist provides clinical benefit with a safety profile similar to placebo.To review published evidence on the ...
Kevin R, Murphy, Bradley E, Chipps
openaire +2 more sources
Improvement of Severe Volume Dependent Airway Closure With Tezepelumab: A Case Report
Clinical Case Reports, Volume 14, Issue 8, August 2026.ABSTRACT Severe asthma may be complicated by airway remodeling, manifesting as higher symptom burden, airflow limitation and reduced treatment response. The effect of biologics on lung function changes remains uncertain. We report a 31‐year‐old man with severe uncontrolled asthma and chronic rhinosinusitis with nasal polyposis, characterized by ...
Philipp Suter +3 more
wiley +1 more source
ChemistryOpen, Volume 15, Issue 8, August 2026.Psoralen (PSN) demonstrates significant dose‐dependent antiemetic activity in a copper sulfate–induced chick emesis model. Integrated in vivo and in silico analyses reveal reduced retching frequency, prolonged latency, and favorable multi‐receptor interactions with D2, 5‐HT3A, and muscarinic receptors, highlighting PSN as a promising multi‐target ...
Kishor Chandra +12 more
wiley +1 more source
British Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 2203-2211, July 2026.Abstract Aim The quantitative effect of several inhibitory drugs on the development of adverse drug reactions (ADRs) is currently difficult to estimate. Our aim was to identify metabolic pathways, which, when inhibited, increase the risk for certain ADRs, and to use this system to consider comedication at individual level. Methods Data of a prospective
Judith Berres +8 more
wiley +1 more source
Tiotropium in chronic obstructive pulmonary disease – a review of clinical development
Respiratory Research, 2020 Background Bronchodilators are the mainstay of pharmacological treatment in chronic obstructive pulmonary disease (COPD), and long-acting muscarinic antagonist (LAMA) monotherapy is recommended as initial treatment for Global Initiative for Chronic ...
Antonio Anzueto, Marc Miravitlles
doaj +1 more source
Food Frontiers, Volume 7, Issue 4, July 2026.Luteolin‐7‐O‐β‐d‐glucuronide mitigates CS‐induced COPD progression by promoting cytokine‐mediated functional cross‐talk between alveolar macrophages and epithelial cells. ABSTRACT Chronic obstructive pulmonary disease (COPD) is associated with inflammation of the airway and lung parenchyma with limited airflow due to continued exposure to harmful ...
Jianhu Jia +13 more
wiley +1 more source
Non‐Linear Dysanaptic Lung Growth in Patients With Post‐Infectious Bronchiolitis Obliterans
Pediatric Pulmonology, Volume 61, Issue 7, July 2026.ABSTRACT Introduction Few studies have assessed longitudinal pulmonary function outcomes in post‐infectious bronchiolitis obliterans (PIBO). This study analyzes pulmonary function changes from patients with PIBO at a single center with respect to time and inciting respiratory pathogen.
James M. Clegg +3 more
wiley +1 more source
Dupilumab Beyond the Airway: Decreased Morbidity in a Real‐World Analysis
International Forum of Allergy &Rhinology, Volume 16, Issue 6, Page 607-614, June 2026.ABSTRACT Background Post hoc analyses of clinical trials have characterized dupilumab's adverse effects, yet the real‐world impact in chronic rhinosinusitis with nasal polyps (CRSwNP) and asthma is not well described. This study aims to characterize the risks of lymphoma, cardiovascular events, eosinophilia, joint pain, inflammatory arthritis, and ...
Emma J. Anisman +9 more
wiley +1 more source
British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1787-1808, June 2026.Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale +5 more
wiley +1 more source
International Journal of COPD, 2019 Martine Hoogendoorn,1 Isaac Corro Ramos,1 Michael Baldwin,2 Laura Luciani,3 Cecile Fabron,4 Bruno Detournay,4 Maureen PMH Rutten-van Mölken1,5 1institute for Medical Technology Assessment (iMTA), Erasmus University Rotterdam, Rotterdam, the ...
Hoogendoorn M +6 more
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