Results 21 to 30 of about 7,681 (214)

Protective effects of tiotropium alone or combined with budesonide against cadmium inhalation induced acute neutrophilic pulmonary inflammation in rats. [PDF]

open access: yesPLoS ONE, 2018
As a potent bronchodilator, the anti-inflammatory effects of tiotropium and its interaction with budesonide against cadmium-induced acute pulmonary inflammation were investigated.
Shiwei Zhao   +6 more
doaj   +1 more source

Effects of tiotropium on the risk of coronary heart disease in patients with COPD: a nationwide cohort study

open access: yesScientific Reports, 2022
Inhaled long-acting muscarinic antagonist (LAMA) is recommended for the treatment of chronic obstructive pulmonary disease (COPD). However, there is still concern that LAMA may cause cardiovascular adverse events in COPD patients.
Jiyoung Shin, Jin Hwa Lee
doaj   +1 more source

Tiotropium in asthma: a systematic review

open access: yesJournal of Asthma and Allergy, 2014
Elizabeth Befekadu,1 Claudia Onofrei,1 Gene L Colice1,2 1MedStar Washington Hospital Center, Washington, DC, USA; 2The George Washington University School of Medicine and Health Sciences, Washington, DC, USA Introduction: The objective of this paper is ...
Befekadu E, Onofrei C, Colice GL
doaj   +2 more sources

The interaction of tiotropium with long lasting β2-agonists on lung cell function [PDF]

open access: yes, 2013
The major question addressed in this thesis was to find the mechanism(s) by which muscarinic receptors interact with β2-adrenergic receptors in human airway fibroblasts.
Costa, Luigi
core   +1 more source

Real-world effectiveness of early intervention with fixed-dose tiotropium/olodaterol vs tiotropium in Japanese patients with COPD: a high-dimensional propensity score–matched cohort analysis

open access: yesRespiratory Research, 2021
Background Escalation to triple therapy (long-acting muscarinic antagonist/β2-agonist, inhaled corticosteroid [ICS]) in chronic obstructive pulmonary disorder (COPD) is recommended for patients on LAMA/LABA combinations with frequent exacerbations and ...
Shigeo Muro   +6 more
doaj   +1 more source

Update on Long-Acting Anticholinergics in Children and Adolescents With Difficult and Severe Asthma

open access: yesFrontiers in Pediatrics, 2022
Tiotropium bromide is the only long-acting muscarinic antagonist (LAMA) approved for treatment of patients aged ≥6 years old who have symptoms of uncontrolled asthma.
Francesca Santamaria   +4 more
doaj   +1 more source

Effect of Tiotropium Bromide on Airway Inflammation and Programmed Cell Death 5 in a Mouse Model of Ovalbumin-Induced Allergic Asthma

open access: yesCanadian Respiratory Journal, 2019
Rationale. We previously demonstrated increased expression of programmed cell death 5 (PDCD5) in asthmatic patients and ovalbumin-induced allergic asthma.
Juan Wang   +3 more
doaj   +1 more source

Skin reaction to inhaled tiotropium bromide: a case report

open access: yesJournal of Medical Case Reports, 2011
Introduction Systemic reactions to inhaled drugs are rare. To the best of our knowledge, we report the first case of generalized itching related to the use of tiotropium bromide, a long acting inhaled anti-cholinergic agent commonly used to treat chronic
Megali Raffaella   +3 more
doaj   +1 more source

Tiotropium [PDF]

open access: yespharma-kritik, 2003
Tiotropium, ein neues Mittel zur Behandlung der chronisch-obstruktiven Lungenkrankheit, hat eine ähnliche Struktur wie Ipratropium, zeichnet sich aber durch eine deutlich längere Halbwertszeit aus und muss deshalb nur einmal pro Tag inhaliert werden. Tiotropium scheint mindestens so wirksam zu sein wie andere Bronchodilatatoren, ist innerhalb dieser ...
openaire   +1 more source

Tiotropium in the add-on treatment of asthma in adults: clinical trial evidence and experience

open access: yesTherapeutic Advances in Respiratory Disease, 2016
Asthma is a chronic inflammatory airway disease, and its treatment is frequently challenging despite detailed national and international guidelines. While basic anti-inflammatory therapy usually consists of inhaled corticosteroids in doses adapted to the
Christian Vogelberg
doaj   +1 more source

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