Results 111 to 120 of about 853 (171)

Estudio de la resistencia a los antifúngicos en hongos patógenos humanos [PDF]

, 2019
Las mejoras en el diagnóstico, el tratamiento y el cuidado de pacientes inmunodeprimidos han incrementado su tasa de supervivencia, pero también han dado lugar al aumento progresivo de otras enfermedades, como las infecciones fúngicas invasoras.
Rivero Menéndez, Olga
core   +1 more source

Clinical characterization and etiological insights: a small cohort study of pulmonary infections caused by Microascus spp. in critically ill patients [PDF]

Microascus spp., globally distributed fungi, are increasingly recognized as causative agents of rare and refractory invasive infections in immunocompromised populations, with approximately 50 cases reported worldwide. This study aimed to characterize the
Jian-Jun Cheng, Jun-Mei Zhu, Li-Ting Zhou, Qing-Zhen Han, Ru-Ru Bi, Ting Zhang, Yan Chen   +6 more
core   +1 more source

A one health roadmap towards understanding and mitigating emerging Fungal Antimicrobial Resistance: fAMR [PDF]

The emergence of fungal antimicrobial resistance-fAMR-is having a growing impact on human and animal health, and food security. This roadmap charts inter-related actions that will enhance our ability to mitigate the risk of fAMR.
Armstrong-James D, Bromley M, Burnett F, Chandler C, Fisher MC, Gow NAR, Gurr S, Hart A, Holmes A, May RC, Quinn J, Soliman T, Talbot NJ, West HM, West JS, White PL   +15 more
core  

Dihydroorotate dehydrogenase inhibitors in anti-infective drug research [PDF]

, 2019
Boschi, D., Lolli, M. L., Pippione, A. C., Sainas, S.   +3 more
core   +1 more source

Fungal lung disease. [PDF]

Fungal lung disease encompasses a wide spectrum of organisms and associated clinical conditions, presenting a significant global health challenge. The type and severity of disease are determined by underlying host immunity and infecting fungal strain ...
Agarwal, Ritesh, Chotirmall, Sanjay, Delhaes, Laurence, Hage, Chadi, Jaggi, Tavleen, Langelier, Charles, Lydon, Emily, Shah, Anand, Tiew, Pei, Waterer, Grant   +9 more
core   +1 more source

Towards covalent inhibition of phosphoglucomutase in Aspergillus fumigatus [PDF]

, 2023
Kowalski, Bartosz
core   +1 more source

P-1238. Assessment of Body Weight upon PK of Olorofim in Patients with Invasive Mould Infections [PDF]

Open Forum Infect Dis
Abstract Background Olorofim (OLO) is a novel antifungal active vs. Aspergillus (including azole-resistant strains), resistant moulds (e.g., Lomentospora prolificans [LoPro]), and dimorphic moulds. Potential impact of bodyweight upon systemic exposure was explored using pharmacokinetic (PK) data from ...
Cornelissen, Karen, Rex, John H, Zinzi, Daniela, Galbraith, Hal, Burt, Howard   +4 more
europepmc   +2 more sources

Disseminated <i>Lomentospora prolificans</i> infection in a patient with neutropenia treated with ipilimumab and nivolumab. [PDF]

BMJ Case Rep
Dunstan NW, Robinson JO, Walczak A, Higgins A, Karthaus M, Ariyapperuma MH.   +5 more
europepmc   +1 more source

Compassionate Use of Olorofim for Invasive Mold Infections: A Nationwide Observational Study in France. [PDF]

Open Forum Infect Dis
Esnault V, Godet C, Garcia-Hermoso D, Charmillon A, Parize P, Bonnal C, Debourgogne A, Morio F, Bougnoux ME, Dannaoui E, Bellanger AP, Gangneux JP, Sendid B, Cardot E, Melenotte C, Rouzaud C, Lefort A, Colin de Verdiere S, Brugiere O, Tetart M, Eschapasse E, Berceanu A, Tattevin P, Levy R, Faure E, Lanternier F.   +25 more
europepmc   +1 more source

In vitro evaluation of olorofim and antifungal combinations against Aspergillus and Candida species. [PDF]

J Antimicrob Chemother
Pinder C, Lebedinec R, Oliver JD, Birch M, Law D.   +4 more
europepmc   +1 more source