Results 161 to 170 of about 853 (171)
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F2G gets $70 million to develop the antifungal olorofim
Chemical & Engineering News, 2022openaire +1 more source
Olorofim activity against multidrug-resistant unveils intra-species and inter-species variability.
Fungi in the genus are plant pathogens but are also capable of causing a wide range of diseases in humans. The intrinsic multi-drug resistance of often leads to a poor clinical outcome in patients with severe immune disorders. Olorofim, a member of the orotomide class, is a novel type of antifungal drug that interferes with pyrimidine biosynthesis by ...Xue, Ruoning +11 more
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Absorption, Metabolism and Excretion of 14C-olorofim in Man
Case Medical Research, 2019openaire +1 more source
Olorofim, a potential novel drug candidate against Helicobacter pylori infection
The Journal of AntibioticsSaba Ghaffari +2 more
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Olorofim: addressing unmet needs of patients with difficult-to-treat fungal infections
The Lancet Infectious DiseasesOlivier Paccoud, Fanny Lanternier
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A difficult-to-treat septic arthritis by Scedosporium apiospermum successfully treated with olorofim
Journal of Antimicrobial ChemotherapyStephany Febles Leyva +5 more
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A Biopharmaceutics Study to Assess the Pharmacokinetics of Single Oral and IV Doses of Olorofim
Case Medical Research, 2019openaire +1 more source

