Results 21 to 30 of about 11,492 (188)

Severe pediatric asthma with a poor response to omalizumab: a report of three cases and three-dimensional bronchial wall analysis

open access: yesJournal of International Medical Research, 2022
Omalizumab is used for the treatment of persistent severe allergic asthma in adults and children. However, some patients remain symptomatic even after omalizumab treatment. In bronchial asthma, chronic inflammation of the bronchial wall causes thickening
Mitsuru Tsuge   +3 more
doaj   +1 more source

Biologics for the treatment of chronic rhinosinusitis with nasal polyps : state of the art [PDF]

open access: yes, 2019
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a complex upper airway disease affecting up to 11% of the population of Western Europe. In these western countries, 85% of the CRSwNP disease reveals a type 2 inflammatory pattern. In the last 15 years,
Bachert, Claus   +3 more
core   +1 more source

Recovery of smell sense loss by mepolizumab in a patient allergic to dermatophagoides and affected by chronic rhinosinusitis with nasal polyps [PDF]

open access: yes, 2019
Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) frequently presents with dysfunction or loss of the sense of smell, resulting in a signifcant impairment in quality of life.
Cavaliere, Carlo   +7 more
core   +1 more source

Atopic Dermatitis Host and Environment Model: Revisiting Therapeutic Options [PDF]

open access: yes, 2020
Atopic Dermatitis affects both children and adults and is a serious health concern in many countries. AD is a complex disease with host and environmental factors underlying its pathology. Its treatment is multidimensional reflecting the diverse nature of
Abreu, C   +3 more
core   +1 more source

Learnings from real-life experience of using omalizumab for chronic urticaria in Latin America

open access: yesWorld Allergy Organization Journal, 2019
Background: Updated urticaria guidelines recommend that patients should be assessed for disease activity, severity, control, and quality of life at baseline and follow up.
Ivan Cherrez-Ojeda   +15 more
doaj   +1 more source

Cost-effectiveness of omalizumab in real world uncontrolled allergic asthma patients

open access: yesPulmonology, 2021
Objective To estimate the cost-effectiveness of omalizumab compared with standard of care in the treatment and control of severe persistent asthma, using the outcomes from the Portuguese subpopulation of the eXpeRience registry.Methods This was a ...
A. Arrobas   +4 more
doaj   +3 more sources

Description of Baseline Characteristics of Pediatric Allergic Asthma Patients Including those Initiated on Omalizumab

open access: yesAllergy & Rhinology, 2018
Background Indication of omalizumab in the United States was recently extended to include pediatric (6–11 years) uncontrolled moderate-to-severe allergic asthma patients.
Abhishek Kavati   +8 more
doaj   +1 more source

Prototype of running clinical trials in an untrustworthy environment using blockchain. [PDF]

open access: yes, 2019
Monitoring and ensuring the integrity of data within the clinical trial process is currently not always feasible with the current research system.
Bhattacharya, Sanchita   +2 more
core   +3 more sources

Treatment of estrogen-induced dermatitis with omalizumab [PDF]

open access: yes, 2019
In 1945, Drs Bernhard Zondek and Yehuda Bromberg demonstrated intradermal treatment with estrone and estradiol benzoate induced urticarial lesions in some patients.1 Fifty years later, Shelley et al,2 who introduced the concept of progesterone dermatitis
Baker, William H.   +5 more
core   +1 more source

Development of Assay for Determining Free IgE Levels in Serum from Patients Treated with Omalizumab

open access: yesAllergology International, 2014
Background: Omalizumab, a monoclonal anti-IgE antibody, is currently indicated for the treatment of moderate-to-severe allergic asthma. To measure active IgE levels in sera from patients treated with omalizumab, the IgE subfraction in complex with ...
Reiko Ito   +9 more
doaj   +1 more source

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