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Acta Crystallographica Section C Crystal Structure Communications, 1999 The title compound (I),9-methoxy-2,4-dimethyl-5-thioxo-5-hydro-pyrido[1',2':3,4] imidazo[1,2-a] benzimidazol-3-one is isolated during impurity profiling of Omeprazole. It is Crystallized from ethanol. The molecule is essentially planar. van der Waals interactions stabilize the molecules in the lattice.
D Sreenivas Rao +4 more
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Equine Veterinary Journal, 2019
BACKGROUND Previous studies have demonstrated a poor response to healing of gastric glandular lesions with oral omeprazole and other medications. OBJECTIVES To evaluate the efficacy of two novel treatments (misoprostol [M] and combined omeprazole ...
G. Varley +4 more
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BACKGROUND Previous studies have demonstrated a poor response to healing of gastric glandular lesions with oral omeprazole and other medications. OBJECTIVES To evaluate the efficacy of two novel treatments (misoprostol [M] and combined omeprazole ...
G. Varley +4 more
semanticscholar +1 more source
Journal of Allergy and Clinical Immunology, 1996
respiratory arrest in young patients with asthma. N Engl J Med 1991;324:359-63. 4. Malling HJ. Diagnosis and immunotherapy of mould allergy. Allergy 1986;41:342-50. 5. Beaumont F, Kauffman H, Sluiter H, de Vries K. Sequential sampling of fungal air spores inside and outside the homes of mold-sensitive asthmatic patients: a search for a relationship to ...
Rita A.S. Phaff +3 more
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respiratory arrest in young patients with asthma. N Engl J Med 1991;324:359-63. 4. Malling HJ. Diagnosis and immunotherapy of mould allergy. Allergy 1986;41:342-50. 5. Beaumont F, Kauffman H, Sluiter H, de Vries K. Sequential sampling of fungal air spores inside and outside the homes of mold-sensitive asthmatic patients: a search for a relationship to ...
Rita A.S. Phaff +3 more
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Journal of Veterinary Internal Medicine, 2015 Background Gastric acid suppressants frequently are used in cats with acid‐related gastric disorders. However, it is not known if these drugs effectively increase intragastric pH in cats.
S. Sutalo +4 more
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Annals of Allergy, Asthma & Immunology, 1999
Omeprazole is a non-competitive inhibitor of the parietal cell enzyme H+-K--adenosine triphosphatase. To date, two cases of angioedema and urticaria and two cases of anaphylaxis from omeprazole have been published.To report a new patient with omeprazole-induced anaphylaxis demonstrated by skin tests and increased serum tryptase levels.Elevated serum ...
R. Garcia +6 more
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Omeprazole is a non-competitive inhibitor of the parietal cell enzyme H+-K--adenosine triphosphatase. To date, two cases of angioedema and urticaria and two cases of anaphylaxis from omeprazole have been published.To report a new patient with omeprazole-induced anaphylaxis demonstrated by skin tests and increased serum tryptase levels.Elevated serum ...
R. Garcia +6 more
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Human & Experimental Toxicology, 1993
The clinical features and pharmacokinetics of omeprazole in overdose have not previously been described. We report 2 cases. The major clinical features were flushing, tachycardia and headache. Omeprazole pharmacokinetics remained unchanged in overdose.
R E, Ferner, T R, Allison
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The clinical features and pharmacokinetics of omeprazole in overdose have not previously been described. We report 2 cases. The major clinical features were flushing, tachycardia and headache. Omeprazole pharmacokinetics remained unchanged in overdose.
R E, Ferner, T R, Allison
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Omeprazole and the Gastric Mucosa
Digestion, 1990The potential for either omeprazole or its sulphenamide to interact with DNA was investigated by incubating tritiated omeprazole at either neutral or acidic pH with either purified prokaryotic (Escherichia coli) or purified eukaryotic (salmon sperm) DNA. Each incubation was carried out for 30 min.
M Reuben, D Scott, Gary S. Sachs
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Equine Veterinary Journal, 2015
REASONS FOR PERFORMING THE STUDY A previous study demonstrated that a dose effect between 1.6 and 4.0 mg/kg bwt of omeprazole per os s.i.d. is present in the treatment of equine gastric ulceration.
B. Sykes, K. M. Sykes, G. Hallowell
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REASONS FOR PERFORMING THE STUDY A previous study demonstrated that a dose effect between 1.6 and 4.0 mg/kg bwt of omeprazole per os s.i.d. is present in the treatment of equine gastric ulceration.
B. Sykes, K. M. Sykes, G. Hallowell
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Oral pharmacokinetics of omeprazole
European Journal of Clinical Pharmacology, 1984The pharmacokinetics of omeprazole were studied in a group of healthy male subjects after single and repeated oral doses of 30 and 60 mg. Absorption of omeprazole from its enteric-coated formulation was unpredictable. There was a highly significant increase in the area under the plasma concentration time curve (AUC) after repeated dosing.
J. A. H. Forrest +3 more
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Solid solution hardening of molecular crystals: tautomeric polymorphs of omeprazole.
Journal of the American Chemical Society, 2015In the context of processing of molecular solids, especially pharmaceuticals, hardness is an important property that often determines the manufacturing steps employed.
M. Mishra, U. Ramamurty, G. Desiraju
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