Results 1 to 10 of about 60,936 (194)

OMG: Open Molecule Generator [PDF]

Journal of Cheminformatics, 2012
Computer Assisted Structure Elucidation has been used for decades to discover the chemical structure of unknown compounds. In this work we introduce the first open source structure generator, Open Molecule Generator (OMG), which for a given elemental ...
Peironcely Julio E, Rojas-Chertó Miguel, Fichera Davide, Reijmers Theo, Coulier Leon, Faulon Jean-Loup, Hankemeier Thomas   +6 more
doaj   +4 more sources

Robotic thymectomy for ocular myasthenia gravis: a case series from a UK tertiary centre [PDF]

BMJ Neurology Open
Background Ocular myasthenia gravis (oMG), characterised by ptosis and diplopia, may progress to generalised MG (gMG). Thymectomy is established for seropositive gMG, but its role in oMG remains unclear.
David Lawrence, Jennifer Spillane, Thomas Roberts, Stephen Cone, Alessandro Maraschi, Kunal Bhakhri   +5 more
doaj   +2 more sources

Ocular myasthenia gravis management [PDF]

Frontiers in Neurology
Ocular myasthenia gravis (OMG) has no agreed-upon diagnostic and management criteria, leading to misdiagnoses and often misguided treatments. The purpose of this minireview is to provide guidance to clinicians who encounter possible OMG patients. We cite
Mark J. Kupersmith, Gil I. Wolfe, Henry Kaminski   +2 more
doaj   +2 more sources

OMG! A proteomic determinant of neurodegenerative resiliency [PDF]

Molecular Neurodegeneration
Background Biofluid proteomics can enhance our understanding of the neurodegenerative mechanisms underlying Alzheimer’s disease and related dementias (ADRDs). Oligodendrocyte myelin glycoprotein (OMG) is a brain-specific protein implicated in myelination,
Michael R. Duggan, Hamilton Se-Hwee Oh, Philipp Frank, Gabriela T. Gomez, David Zweibaum, Yuhan Cui, Jingsha Chen, Aditya Surapaneni, Cassandra O. Blew, Heather E. Dark, Cassandra M. Joynes, Sridhar Kandala, Murat Bilgel, Amelia Farinas, Guray Erus, Qu Tian, Julián Candia, Krishna A. Pucha, Bennett A. Landman, Logan Dumitrescu, Timothy J. Hohman, Alexandria Lewis, Abhay Moghekar, Fatemeh Siavoshi, Muhammad Ali, Menghan Liu, Ying Xu, Daniel Western, Naoto Kaneko, Shintaro Kato, Makio Furuichi, Masaki Shibayama, Masahisa Katsuno, Yukiko Nishita, Rei Otsuka, Rebecca F. Gottesman, Eric B. Dammer, Nicholas T. Seyfried, Allan I. Levey, Erik C. B. Johnson, Elizabeth Mormino, Anthony D. Wagner, Kathleen L. Poston, Dimitrios Kapogiannis, Morgan E. Grams, Pavan Bhargava, Iwao Waga, Christos Davatzikos, Susan M. Resnick, Luigi Ferrucci, David A. Bennett, Carlos Cruchaga, Tony Wyss-Coray, Mika Kivimäki, Josef Coresh, Keenan A. Walker   +55 more
doaj   +2 more sources

Evaluating the Effectiveness of Large Language Models in Providing Patient Education for Chinese Patients With Ocular Myasthenia Gravis: Mixed Methods Study [PDF]

Journal of Medical Internet Research
BackgroundOcular myasthenia gravis (OMG) is a neuromuscular disorder primarily affecting the extraocular muscles, leading to ptosis and diplopia.
Bin Wei, Lili Yao, Xin Hu, Yuxiang Hu, Jie Rao, Yu Ji, Zhuoer Dong, Yichong Duan, Xiaorong Wu   +8 more
doaj   +2 more sources

Transport and expression of transporters for 3-O-methyl-D-glucose and L-methionine along the intestine of broiler chickens receiving different methionine supplements [PDF]

Poultry Science
The present study hypothesized that supplementation of different methionine (Met) sources might influence the intestinal absorption of L-Met and 3-O-methyl-D-glucose (3-OMG) in broilers.
Julia Riedel, Isabel I. Schermuly, Stella Romanet, Eva-Maria Saliu, Andreas Lemme, Jürgen Zentek, Jörg R. Aschenbach   +6 more
doaj   +2 more sources

Desarrollo de nuevos diseños vegetales: Mejora genética vs transformación genética y edición génica

Magna Scientia UCEVA, 2021
El objetivo de esta reflexión es realizar un estudio comparativo sobre la eficacia, eficiencia técnica y costo de las tecnologías más importantes para el desarrollo de nuevos diseños vegetales, incluyendo la mejora genética, la transformación genética y ...
Pedro Martínez Gómez
doaj   +1 more source

Striatal Transcriptome Reveals Differences Between Cognitively Impaired and Unimpaired Aged Male Rats

Frontiers in Aging Neuroscience, 2021
Cognitive processes require striatal activity. The underlying molecular mechanisms are widely unknown. For this reason the striatal transcriptome of young (YM), aged cognitively impaired (OMB), and unimpaired (OMG) male rats was analyzed.
Volker Korz, Christopher Kremslehner, Jovana Maliković, Ahmed Hussein, Daniel Daba Feyissa, Ionela-Mariana Nagelreiter, Ionela-Mariana Nagelreiter, Roman Smidak, Roberto Plasenzotti, Florian Gruber, Gert Lubec   +10 more
doaj   +1 more source

Omarigliptin Mitigates 6-Hydroxydopamine- or Rotenone-Induced Oxidative Toxicity in PC12 Cells by Antioxidant, Anti-Inflammatory, and Anti-Apoptotic Actions

Antioxidants, 2022
Dipeptidyl peptidase-4 (DPP-4) inhibitors are reported to exhibit promising effects on several pathological processes associated with Parkinson’s disease (PD).
Noha A. Gouda, Jungsook Cho
doaj   +1 more source

Immunotherapy for ocular myasthenia gravis: an observational study in Japan

Therapeutic Advances in Neurological Disorders, 2023
Background: Treatment for ocular myasthenia gravis (OMG) has not yet been well established. Few reports have been published on the clinical practice and outcomes of OMG. Objectives: We investigated treatment of OMG and its outcomes in Japan.
Tomoko Narita, Shunya Nakane, Akiko Nagaishi, Naoya Minami, Masaaki Niino, Naoki Kawaguchi, Hiroyuki Murai, Jun-ichi Kira, Jun Shimizu, Kazuo Iwasa, Hiroaki Yoshikawa, Yuki Hatanaka, Masahiro Sonoo, Yuko Shimizu, Hidenori Matsuo   +14 more
doaj   +1 more source