Results 1 to 10 of about 3,835 (176)

OMG! A proteomic determinant of neurodegenerative resiliency [PDF]

Molecular Neurodegeneration
Background Biofluid proteomics can enhance our understanding of the neurodegenerative mechanisms underlying Alzheimer’s disease and related dementias (ADRDs). Oligodendrocyte myelin glycoprotein (OMG) is a brain-specific protein implicated in myelination,
Michael R. Duggan, Hamilton Se-Hwee Oh, Philipp Frank, Gabriela T. Gomez, David Zweibaum, Yuhan Cui, Jingsha Chen, Aditya Surapaneni, Cassandra O. Blew, Heather E. Dark, Cassandra M. Joynes, Sridhar Kandala, Murat Bilgel, Amelia Farinas, Guray Erus, Qu Tian, Julián Candia, Krishna A. Pucha, Bennett A. Landman, Logan Dumitrescu, Timothy J. Hohman, Alexandria Lewis, Abhay Moghekar, Fatemeh Siavoshi, Muhammad Ali, Menghan Liu, Ying Xu, Daniel Western, Naoto Kaneko, Shintaro Kato, Makio Furuichi, Masaki Shibayama, Masahisa Katsuno, Yukiko Nishita, Rei Otsuka, Rebecca F. Gottesman, Eric B. Dammer, Nicholas T. Seyfried, Allan I. Levey, Erik C. B. Johnson, Elizabeth Mormino, Anthony D. Wagner, Kathleen L. Poston, Dimitrios Kapogiannis, Morgan E. Grams, Pavan Bhargava, Iwao Waga, Christos Davatzikos, Susan M. Resnick, Luigi Ferrucci, David A. Bennett, Carlos Cruchaga, Tony Wyss-Coray, Mika Kivimäki, Josef Coresh, Keenan A. Walker   +55 more
doaj   +4 more sources

Comparative study of ocular and generalized myasthenia gravis in a South Korean cohort. [PDF]

PLoS ONE
PurposeTo compare ocular myasthenia gravis (OMG) and generalized myasthenia gravis (GMG) in a South Korean cohort through an integrated analysis of clinical characteristics, diagnostic findings, and treatment patterns.MethodsWe conducted a retrospective ...
Chaerin Kwon, Jeeyoung Oh, Hyun Jin Shin
doaj   +2 more sources

Validation and clinical utility of OMGRate and MG-QOL15 in evaluating symptoms and quality of life in Chinese patients with ocular myasthenia gravis [PDF]

Frontiers in Neurology
PurposeThis study aimed to evaluate the value of the OMGRate and MG-QOL 15 in assessing quality of life (QoL) before and after treatment in ocular myasthenia gravis (OMG) and to validate the applicability of OMGRate in the Chinese OMG population ...
Ting Tang, Qiwen Feng, Qiwen Feng, Youran Cai, Yuying Dong, Jian Chen, Rijia Zhang, Qing Zhou   +7 more
doaj   +2 more sources

OMG: Open Molecule Generator [PDF]

Journal of Cheminformatics, 2012
Computer Assisted Structure Elucidation has been used for decades to discover the chemical structure of unknown compounds. In this work we introduce the first open source structure generator, Open Molecule Generator (OMG), which for a given elemental ...
Peironcely Julio E, Rojas-Chertó Miguel, Fichera Davide, Reijmers Theo, Coulier Leon, Faulon Jean-Loup, Hankemeier Thomas   +6 more
doaj   +4 more sources

Robotic thymectomy for ocular myasthenia gravis: a case series from a UK tertiary centre [PDF]

BMJ Neurology Open
Background Ocular myasthenia gravis (oMG), characterised by ptosis and diplopia, may progress to generalised MG (gMG). Thymectomy is established for seropositive gMG, but its role in oMG remains unclear.
David Lawrence, Jennifer Spillane, Thomas Roberts, Stephen Cone, Alessandro Maraschi, Kunal Bhakhri   +5 more
doaj   +2 more sources

Ocular myasthenia gravis management [PDF]

Frontiers in Neurology
Ocular myasthenia gravis (OMG) has no agreed-upon diagnostic and management criteria, leading to misdiagnoses and often misguided treatments. The purpose of this minireview is to provide guidance to clinicians who encounter possible OMG patients. We cite
Mark J. Kupersmith, Gil I. Wolfe, Henry Kaminski   +2 more
doaj   +2 more sources

Proanthocyanidin-Rich Cranberry Extract Lowers Glycemia in Established Obesity by Delaying Glucose Absorption. [PDF]

FASEB J
Schematic summary of the metabolic effects and proposed mechanisms of action of proanthocyanidin‐rich cranberry extract (PRCE) supplementation in mice with established diet‐induced obesity housed under thermoneutral (30°C) or cold‐exposed (10°C) conditions.
Beji S, Mouchiroud M, Tribouillard L, Efole B, Perazza L, Favereaux L, Poirier A, Idris W, Gélinas Y, Varin TV, Rovère C, Anhê FF, Picard F, Laplante M, Marette A, Michaud A, Caron A.   +16 more
europepmc   +2 more sources

Desarrollo de nuevos diseños vegetales: Mejora genética vs transformación genética y edición génica

Magna Scientia UCEVA, 2021
El objetivo de esta reflexión es realizar un estudio comparativo sobre la eficacia, eficiencia técnica y costo de las tecnologías más importantes para el desarrollo de nuevos diseños vegetales, incluyendo la mejora genética, la transformación genética y ...
Pedro Martínez Gómez
doaj   +1 more source

Striatal Transcriptome Reveals Differences Between Cognitively Impaired and Unimpaired Aged Male Rats

Frontiers in Aging Neuroscience, 2021
Cognitive processes require striatal activity. The underlying molecular mechanisms are widely unknown. For this reason the striatal transcriptome of young (YM), aged cognitively impaired (OMB), and unimpaired (OMG) male rats was analyzed.
Volker Korz, Christopher Kremslehner, Jovana Maliković, Ahmed Hussein, Daniel Daba Feyissa, Ionela-Mariana Nagelreiter, Ionela-Mariana Nagelreiter, Roman Smidak, Roberto Plasenzotti, Florian Gruber, Gert Lubec   +10 more
doaj   +1 more source

Advocating Patient-Centred Research in Ocular Myasthenia Gravis (OMG): A Call for an OMG Research Consortium

Frontiers in Ophthalmology, 2022
Sui H Wong
exaly   +3 more sources