Results 41 to 50 of about 60,936 (194)

A case study on the transformation of context-aware domain data onto XML schemas [PDF]

open access: yes, 2007
In order to accelerate the development of context-aware applications, it would be convenient to have a smooth path between the context models and the automated services that support these models. This paper discusses how MDA technology (metamodelling and
Ferreira Pires, L.   +2 more
core   +2 more sources

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo   +9 more
wiley   +1 more source

Comparison of olive leaf, olive oil, palm oil, and omega-3 oil in acute kidney injury induced by sepsis in rats [PDF]

open access: yesPeerJ, 2019
Background Hypotension, increased production of reactive oxygen species, and inflammation are all observed in experimental models of sepsis induced by lipopolysaccharide (LPS).
Maria Fátima de Paula Ramos   +9 more
doaj   +2 more sources

Reliability prediction in model driven development [PDF]

open access: yes, 2005
Evaluating the implications of an architecture design early in the software development lifecycle is important in order to reduce costs of development.
Rodrigues, G.N.   +2 more
core   +1 more source

GMO or OMG? [PDF]

open access: yesIEEE Pulse, 2019
Just when it looked like there could be a breakthrough in the application of biotechnology to crops and food plants, a new wrinkle appeared in the form of a scientific development. Genetically modified organisms (GMOs) have been planted for years because they offer advantages for producers or consumers.
openaire   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin   +11 more
wiley   +1 more source

The octet rule in chemical space: Generating virtual molecules

open access: yes, 2017
We present a generator of virtual molecules that selects valid chemistry on the basis of the octet rule. Also, we introduce a mesomer group key that allows a fast detection of duplicates in the generated structures. Compared to existing approaches, our
Hamaekers, Jan   +2 more
core   +1 more source

An elastic segment of the whisker shaft enables coding of the whisking phase via whisker torsion in rats and mice

open access: yesThe Anatomical Record, EarlyView.
An elastic segment was found in the basal part of the whisker shaft in rats and mice. Application of force to the whisker bulb of isolated follicles caused bending and twisting of this segment. Active whisker movements deform this segment, causing whisker shaft deflection and selective activation of mechanoreceptors at different phases of whisking ...
Sebastian Haidarliu   +4 more
wiley   +1 more source

AADLib, A Library of Reusable AADL Models [PDF]

open access: yes, 2013
The SAE Architecture Analysis and Design Language is now a well-established language for the description of critical embedded systems, but also cyber-physical ones.
Hugues, Jérôme
core   +1 more source

Valorization of Yacon (Smallanthus sonchifolius) peel for peroxidase production and its immobilization on alginate beads for 2,4‐dichlorophenol bioconversion

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Sodium alginate was modified with EDC/NHS for the immobilization of Yacon peel peroxidase, resulting in a novel biocatalyst for the oxidation of 2,4‐dichlorophenol. Abstract Yacon (Smallanthus sonchifolius) roots are emerging as an alternative source of peroxidase. This study aimed to extract, immobilize, and characterize the peroxidase from Yacon peel,
Mariana Gomes Oliveira   +4 more
wiley   +1 more source

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