Results 201 to 210 of about 124,278 (281)

CD56bright NK cells are negatively associated with antibody response to vaccination in people with multiple sclerosis on B‐cell‐depleting therapy

Clinical &Translational Immunology, Volume 15, Issue 2, 2026.
Antibody response to vaccination in people with multiple sclerosis receiving B‐cell depletion therapy is associated with B‐cell frequency but not time since B‐cell depletion. Immunoregulatory CD56bright NK cells may negatively impact antibody responses in this group.
Griffith B Perkins, Christopher M Hope, Cheng Sheng Chai, Matthew J Tunbridge, Sebastian Sterling, Kevin Webb, Joey Yap, Arthur Eng Lip Yeow, Makutiro G Masavuli, Jacqueline Scaffidi, James D Zuiani, Anouschka Akerman, Anupriya Aggarwal, Vanessa Milogiannakis, Matthew B Roberts, Plinio R Hurtado, Stuart Turville, Branka Grubor‐Bauk, Simon C Barry, Janakan Ravindran, Patrick Toby Coates, Pravin Hissaria   +21 more
wiley   +1 more source

Correction to: Comment on: Antiviral effect of Evusheld in COVID-19 hospitalized patients infected with pre-Omicron or Omicron variants: a modelling analysis of the randomized DisCoVeRy trial. [PDF]

J Antimicrob Chemother
europepmc   +1 more source

A booster dose of an inactivated SARS-CoV-2 vaccine targeting virus variants sustains protective humoral and cellular immunity. [PDF]

BMC Med
Méndez C, Rodríguez-Guilarte L, Palacios PA, Gutierrez-Vera C, Román F, Moreno-Tapia D, Ríos M, Reyes A, Cancino FA, Otero FF, Zurita C, Rivera D, Cabrera A, Duarte LF, Urzúa M, Iturriaga C, Rojas Á, Perez CM, Redlich AS, Fasce RA, Fernández J, Mora J, Ramírez E, Domínguez A, Weiskopf D, Grifoni A, Sette A, Zeng G, Meng W, Goldbatt D, Johnson M, CoronaVarCL study group, González-Aramundiz JV, Álvarez-Figueroa MJ, Abarca K, Carreño LJ, González PA, Kalergis AM, Peñaloza HF, Bueno SM.   +39 more
europepmc   +1 more source

Neutralization susceptibility of Omicron lineages

Nature Reviews Immunology, 2022
openaire   +2 more sources

Comparing Cross‐Sectional and Longitudinal Study Designs for Accurate Viral Dynamics Estimation: Insights From the NBA Cohort Data

Journal of Medical Virology, Volume 98, Issue 2, February 2026.
ABSTRACT Viral load data provide critical insights into host‐pathogen interactions and guide clinical and public health decisions. Because frequent testing is often infeasible, viral dynamics models are used to reconstruct infection trajectories, but optimal sampling strategies remain unclear.
Jihyeon Kim, Hyeongki Park, Hoong Kai Chua, Yuqian Wang, Shingo Iwami, Yong Dam Jeong, Koya Ariyoshi, Po Ying Chia, Barnaby E. Young, Matthew E. Cove, Robin N. Thompson, William Hart, Il Hyo Jung, Kwang Su Kim, Hyojung Lee, Keisuke Ejima   +15 more
wiley   +1 more source

Tracking the pandemic through molecular and sequencing tools: a story of SARS- CoV-2 over five years, lessons learned, and further directions. [PDF]

BMC Infect Dis
Khan S, Faruqui H, Zahid M, Chaudhry S, Rehman Z, Noor H, Naushad M.   +6 more
europepmc   +1 more source

Progress in RNA‐Targeted Therapeutics for Human Diseases

MedComm, Volume 7, Issue 2, February 2026.
RNA‐targeted therapies are revolutionizing molecular medicine by transitioning from a “protein‐centric” focus to an “RNA‐regulatory network” approach. Leveraging RNA's diverse roles in gene regulation, signaling, and epigenetic modifications, advanced platforms such as ASOs, siRNA, miRNA, mRNA, aptamers, shRNA, and CRISPR/Cas systems are enabling ...
Wangzheqi Zhang, Aimin Jiang, Bin‐Kui Jia, Yuming Jin, Yinghu Chen, Zhaoyu Li, Yan Liao, Haoling Zhang, Zhiheng Lin, Xiao Fang, Linhui Wang   +10 more
wiley   +1 more source

Accelerate the Highly Efficient Development of mRNA Vaccines Through Advanced Computational Methods

MedComm, Volume 7, Issue 2, February 2026.
This review explores the recent advancements in applying computational methods to optimize mRNA vaccines, with a primary focus on improvements in sequence design and delivery systems. ABSTRACT mRNA medicine is an emerging therapeutic approach that utilizes messenger RNA to synthesize functional proteins directly within target cells.
Ruichu Gu, Duanmiao Si, Dingwei Lei, Xiaoxue Xie, Yongge Li, Han Wen   +5 more
wiley   +1 more source

Predictive markers of SARS-CoV-2 spike-specific cytotoxic T cell activity following Omicron breakthrough infection. [PDF]

Emerg Microbes Infect
Holder KA, Ings DP, Hatfield KM, Fifield KE, Barnes DA, Barnable KA, Harnum DOA, Grant MD.   +7 more
europepmc   +1 more source

Selective and Tunable Routes for Glucose to Fructose Conversion Using MgCl2 Catalysis and Comparison to Other Metal Ions

ChemistryOpen, Volume 15, Issue 2, February 2026.
MgCl2 is a cheap catalyst for glucose to fructose conversion in water with excellent selectivity if competing pathways leading to CC bond breakage avoided by control of pH and oxygen and use of mild temperatures. Both a stereoselective 1,2‐hydride shift and isomerization via an enediol intermediate contribute to the isomerization.
Ramesh Maragani, Sebastian Meier
wiley   +1 more source