Results 121 to 130 of about 407,505 (399)
Microphysiological Systems of Lymphatics and Immune Organs
Advanced Healthcare Materials, EarlyView.This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain +2 more
wiley +1 more source
Advances in single-cell multi-omics methods and their applications in developmental biology [PDF]
, 2020 Xin Cheng, Rui Yan, Fan Guo
openalex +1 more source
Multi-omics approaches to disease
Genome Biology, 2017 High-throughput technologies have revolutionized medical research. The advent of genotyping arrays enabled large-scale genome-wide association studies and methods for examining global transcript levels, which gave rise to the field of “integrative ...
Y. Hasin, M. Seldin, A. Lusis
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.A bone substitute with gentamicin physically precipitated onto the surface of carbonate apatite exhibits prompt drug release, high bactericidal activity, and osteogenic capacity. Efficient antibacterial activity mitigates early postoperative neutrophil accumulation, the status of which may serve as a potential parameter for evaluating the antibacterial
Linghao Xiao +6 more
wiley +1 more source
A fast, scalable and versatile tool for analysis of single-cell omics data
Nature MethodsSingle-cell omics technologies have revolutionized the study of gene regulation in complex tissues. A major computational challenge in analyzing these datasets is to project the large-scale and high-dimensional data into low-dimensional space while ...
Kai Zhang +3 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim +6 more
wiley +1 more source
The role of genetic polymorphisms on drug response in Alzheimer’s disease: a systematic review
BMC Medical GenomicsAlzheimer’s disease (AD) is the most common neurodegenerative disorder, affecting over 32 million people globally. The variability in treatment response to AD medications is influenced by genetic factors, sex, comorbidities, and medication history ...
Fresthel Monica M. Climacosa +12 more
doaj +1 more source
Systematic review on citizens’ literacy in omic sciences and web search of initiatives to improve it [PDF]
, 2020 Michele Sassano +5 more
openalex +1 more source
Isolation Defines Identity: Functional Consequences of Extracellular Vesicle Purification Strategies
Advanced Healthcare Materials, EarlyView.Four extracellular vesicle purification strategies are compared using ovarian‐cancer ascites and ES‐2 cell supernatants. A novel workflow links purification to function by combining particle‐normalized proteomics with matched cell‐free and cell‐based assays.
Christian Preußer +10 more
wiley +1 more source
An evaluation of the National Institutes of Health grants portfolio: identifying opportunities and challenges for multi-omics research that leverage metabolomics data [PDF]
, 2022 Catherine T. Yu +9 more
openalex +1 more source