Results 161 to 170 of about 77,382 (200)

ZBED6-IGF2-PIK3C3 autophagy axis drives ccRCC progression: A multi-omics integration study. [PDF]

iScience
Qi X, Li G, Liu Y, Sun J, Liu Y, Han Y, Wang Q, Chen F, Ren X, Che X, Wu G.   +10 more
europepmc   +1 more source

Multi-omics integration reveals that pyrimidine metabolism in lung adenocarcinoma drives an immunosuppressive microenvironment. [PDF]

iScience
Liu M, Li H, Xu S, Zhou Y, Yao M, Shi J, Zhong L.   +6 more
europepmc   +1 more source

Trans-Omics Integration Reveals That the Kidney Contributes to Systemic Aging via Sexually Dimorphic Accumulation of Glycosphingolipids. [PDF]

MedComm (2020)
Ni Z, Cao C, Tian Y, Mu J, Tian H, Wang Z, Zhang S, Cao M, Yang Y, Lim WLF, Cui J, Sun H, Miao H, Wang Y, Du J, Kwok T, Chen H, Lam SM, Shui G.   +18 more
europepmc   +1 more source

Multi-omics integration in biomedical research – A metabolomics-centric review

Analytica Chimica Acta, 2021
Recent advances in high-throughput technologies have enabled the profiling of multiple layers of a biological system, including DNA sequence data (genomics), RNA expression levels (transcriptomics), and metabolite levels (metabolomics).
Maria A Wörheide, Jan Krumsiek, Gabi Kastenmuller   +2 more
exaly   +2 more sources

Prospects and challenges of multi-omics data integration in toxicology

Archives of Toxicology, 2020
Exposure of cells or organisms to chemicals can trigger a series of effects at the regulatory pathway level, which involve changes of levels, interactions, and feedback loops of biomolecules of different types.
Sebastian Canzler, Jana Hertel, Wibke Busch   +2 more
exaly   +2 more sources

CLCLSA: Cross-omics linked embedding with contrastive learning and self attention for integration with incomplete multi-omics data

Computers in Biology and Medicine
Integration of heterogeneous and high-dimensional multi-omics data is becoming increasingly important in understanding etiology of complex genetic diseases.
Anqi Liu, Xiao Zhang, Zhengming Ding
exaly   +2 more sources

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Integrating Omics: The Future of IBD?

Digestive Diseases, 2014
The complexity of IBD is well recognized as are the putative four major components of its pathogenesis, i.e. environment, genetic makeup, gut microbiota and mucosal immune response. Each of these components is extremely complex on its own, and at present should be more appropriately defined by the terms ‘exposome', ‘genome', ‘microbiome' and ‘immunome',
openaire   +2 more sources

Integration of OMICS Technologies for Crop Improvement

Protein & Peptide Letters, 2021
Sustainable crop improvement can help to feed the exploding human population in an era of shrinking cultivable lands and dwindling water resources. In this scenario, crop improvement using OMICS technologies may help to ensure food security and alleviate the rural poverty in poor countries.
Amna Faryad, Faiza Aziz, Jannat Tahir, Maimoona Kousar, Muhammad Qasim, Aysha Shamim   +5 more
openaire   +2 more sources

Transforming Clinical Research: The Power of High-Throughput Omics Integration

Proteomes
High-throughput omics technologies have dramatically changed biological research, providing unprecedented insights into the complexity of living systems.
Rui Vitorino, Vitorino Rui
exaly   +2 more sources