Results 131 to 140 of about 169,926 (265)

Impact of exercise training on tumour‐infiltrating T cells in human prostate cancer: A secondary analysis of a randomized controlled trial (PRO‐TEST)

Experimental Physiology, EarlyView.
Abstract Exercise training reduces tumour growth by increasing tumour‐infiltrating T‐cell density in preclinical models. However, it remains unknown whether exercise training can modify intratumoural T cells in humans.The aim of this study was to compare the effects of an exercise training intervention versus control on human prostate intratumoural T ...
Simon Nørskov Thomsen, Emil Wriedt, Marianne Gardar Stærk, Sissal Sigmundsdottir Djurhuus, Birgitte Grønkær Toft, Sabrina Wielsøe, Andreas Røder, Thomas Hasselager, Peter Busch Østergren, Henrik Jakobsen, Klaus Brasso, Jesper Frank Christensen, Louise Lang Lehrskov, Casper Simonsen   +13 more
wiley   +1 more source

Pregnancy shifts endothelial progenitor cell morphology and function: Role of metabolism, pro‐inflammatory cytokines and fetal sex

The Journal of Physiology, EarlyView.
Abstract figure legend We recruited non‐pregnant women (NP), women in early pregnancy (EP) and late pregnancy (LP) for isolation of endothelial colony forming cells (ECFCs) via density gradient centrifugation. Plasma supernatant was collected for analysis of markers of glucose and lipid metabolism (fasting glucose, triglycerides, cholesterol, low ...
Marie‐Therese Weiser‐Fuchs, Andreas Jantscher, Simone Tischler, Elena Osto, Lusik Balayan, Hubert Scharnagl, Gabriele Jäger, Bettina Amtmann, Azra Kulovic‐Sissawo, Sabrina Puster, Herbert Fluhr, Barbara Obermayer‐Pietsch, Christina Stern, Ursula Hiden, Evelyn Jantscher‐Krenn   +14 more
wiley   +1 more source

Evaluation of Acute Exposure to Combustible and Novel Tobacco Products Using an In Vitro Human Airway Organ Tissue Equivalent Model

Journal of Applied Toxicology, Volume 46, Issue 5, Page 1548-1565, May 2026.
ABSTRACT Despite the well‐known risks of tobacco use, tobacco exposure remains a major contributor to morbidity and mortality worldwide. Although cigarette use has declined, the popularity of novel tobacco products (NTPs), such as electronic cigarettes (ECs) and heated tobacco products (HTPs), has increased.
Timothy S. Leach, Steven Albertson, Phillip W. Clapp, Vikram Surendran, Trang Simon, Eric C. Donny, Stephen J. Walker, Anthony Atala, Sean V. Murphy   +8 more
wiley   +1 more source

Daytime Ionospheric Density Enhancement Driven by Poleward Neutral Wind Shear Associated With Gravity Waves During the November 2025 Geomagnetic Storm

Geophysical Research Letters, Volume 53, Issue 7, 16 April 2026.
Abstract The threefold daytime electron density increases, along with strong poleward meridional winds exceeding 200 m/s were captured by Sanya Incoherent Scatter Radar (SYISR) during the geomagnetic storm of 12 November 2025. The great ionospheric enhancements were extending to mid‐latitudes over 40° observed by total electron content (TEC) from ...
Qi Jiang, Jiuhou Lei, Zhongli Li, Fuqing Huang, Rong Xia, Tong Dang, Xinan Yue, Xiaoli Luan   +7 more
wiley   +1 more source

Outcomes and risk factors of hemorrhage in patients with resected brain metastases

International Journal of Cancer, Volume 158, Issue 8, Page 2120-2138, 15 April 2026.
What's New? Brain metastases may present with hemorrhage, yet risk factors and clinical outcomes remain unclear. Based on a cohort of 880 patients with resected brain metastases, this study identified tumor volume and primary tumor histology (melanoma and non‐small cell lung cancer) as key predictors of hemorrhage.
Melisa S. Guelen, Kiarash Ferdowssian, Niklas Jung, Hava N. Celik, Andrea Dell'Orco, Semil Eminovic, Anton Früh, Majd Samman, Güliz Acker, Arend Koch, Helena Radbruch, Michael Scheel, Mike P. Wattjes, Julia Onken, Peter Vajkoczy, Nils Hecht, Jawed Nawabi, David Wasilewski   +17 more
wiley   +1 more source

BPM31510 Increases the CoQ Pool in Chemically Induced CoQ‐Deficient Cells, CoQ‐Deficient Patient Fibroblasts, and in Metabolically Active Murine Tissues

The FASEB Journal, Volume 40, Issue 7, 15 April 2026.
Graphical abstract illustrating the in vitro and in vivo experimental workflow used to compare BPM31510, a nanoliposomal formulation of oxidized CoQ10, with conventional CoQ10. Chemically induced CoQ‐deficient SH‐SY5Y cells, CoQ‐deficient patient fibroblasts, and C57BL/6J mice receiving oral CoQ10 or intraperitoneal BPM31510 were subjected to plasma ...
Juan J. Aristizabal‐Henao, Sarah R. Wessel, Sylwia A. Stopka, Srada Karmacharya, Devon Van Cura, Alba Pesini, Kelsey R. Nickerson, Kashni Grover, Oksana Zavidij, Archna Ravi, Andressa L. Mota, Kenneth M. Rosen, Maria‐Dorothea Nastke, Megan K. Cox, Niven R. Narain, Vijay Modur, Catarina M. Quinzii, Stephane Gesta, Michael A. Kiebish   +18 more
wiley   +1 more source

Psilocybin Production With Genetically Modified Aspergillus nidulans Under Pressurized Conditions

Biotechnology and Bioengineering, Volume 123, Issue 4, Page 886-898, April 2026.
Shake flask cultures of psilocybin‐producing A. nidulans were investigated with respect to nitrogen source, rheology, power input, and oxygen availability, and subsequently scaled to a stirred tank reactor scale based on specific power input to develop and optimize a pressurized bioprocess.
Sophie Weiser, Sidney Jung, Bettina Bardl, Johann E. Kufs, Slavica Janevska, Vito Valiante, Dirk Hoffmeister, Lars Regestein   +7 more
wiley   +1 more source

Cystatin B Attenuates Cerebral Ischemia Reperfusion Injury by Inhibiting the JAK2/STAT3 Signaling Pathway

CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
Using experimental models of stroke, we demonstrate that Cystatin B (CSTB) alleviates brain injury following cerebral ischemia reperfusion. This protection is mediated by inhibiting the JAK2/STAT3 signaling pathway, which reduces neuroinflammation and neuronal apoptosis. Our findings highlight CSTB as a promising therapeutic target for ischemic stroke.
Gang Zhou, Fengjiao Hu, Ju Gao, Lei Wang, Xiangbo Wu, Yu Tian, Peng Zhang, Guangming Xia, Feng Wan, Jinhua Wang   +9 more
wiley   +1 more source

What Is Your Diagnosis? Splenic Mass in an African Pygmy Hedgehog

Veterinary Clinical Pathology, EarlyView.
Gabriela Hartmann, Milena Carolina Paz, Paola Sônego, Ana Carolina Contri Natal, Lívia Surita, Marcele Bettim Bandinelli, Luciana Sonne   +6 more
wiley   +1 more source

Effects of Whole‐Body Vibration on Lower‐Limb Muscle Activity in a Flywheel Half‐Squat

European Journal of Sport Science, Volume 26, Issue 4, April 2026.
ABSTRACT Strength and conditioning professionals continuously seek innovative strategies to enhance neuromuscular performance. This study examined muscle activation in the rectus femoris (RF), vastus lateralis (VL), vastus medialis (VM), biceps femoris (BF), gluteus maximus (GMAX), gastrocnemius medialis (GASMED), and gastrocnemius lateralis (GASLAT ...
Clàudia Baraut, Bernat Buscà, Joan Aguilera‐Castells, Margaret T. Jones, Julio Calleja‐González, Faith Brown, Jordi Arboix‐Alió   +6 more
wiley   +1 more source