Results 151 to 160 of about 1,399,412 (310)

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Non-Contact Measurement and Analysis of Machine Tool Spindles [PDF]

An increasing demand on the manufacturing industry to produce tighter tolerance parts at a consistent rate means it is necessary to gain a greater understanding of machine tool capabilities, error sources and factors affecting asset availability.
Clough, David A
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Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Bayesian machine learning for measurement noise estimation of focus variation microscopy instrument

Measurement + Control
ISO 25178-600 is an international standard explaining metrological characteristics that are applied to calibrate the optical areal surface topography measuring instruments.
Anas Alburayt, Wahyudin P. Syam
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Evaluation and Comparison of a Large Machine Tool Structure with ISO Standard Alignment Tests [PDF]

, 2009
In order to satisfactorily machine precision components it is necessary for machine tools to be able to achieve extremely high levels of geometric accuracy.
Longstaff, Andrew P., Myers, A., Barrans, Simon, Longstaff, A. P., Fletcher, Simon, Barrans, S. M., Fletcher, S., Ford, Derek G., Ford, D. G., Myers, Alan   +9 more
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Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Review of the application of high temperature superconductors in coated conductor development and the measurement of their properties [PDF]

, 2005
Since the 1960s, Nb-Ti, exhibiting a superconducting transition temperature Tc of 9K, and Nb3Sn, with a Tc of 18K have been the materials of choice for superconducting applications.
Bruneel, ElsWE068010009432800000-0002-6527-004XF4C6AE2E-F0ED-11E1-A9DE-61C894A0A6B4, Van Driessche, IsabelWE06WE51WE628010007010830000-0001-5253-3325F4614F2A-F0ED-11E1-A9DE-61C894A0A6B4, Penneman, Greet, Van Driessche, Isabel, Hoste, Serge, Hoste, SergeUGent801000316824972603757559F3AECC4C-F0ED-11E1-A9DE-61C894A0A6B4, Bruneel, Els, Schoofs, Bart8010017085706F8A37BC-B25E-11E6-B104-2D2FD0AF0289, Schoofs, Bart, Penneman, Greet80100150123472FD2896-B25E-11E6-B104-2D2FD0AF0289   +9 more
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RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Representing the Process of Machine Tool Calibration in First-order Logic [PDF]

, 2011
Machine tool calibration requires a wide range of measurement techniques that can be carried out in many different sequences. Planning a machine tool calibration is typically performed by a subject expert with a great understanding of International ...
Longstaff, Andrew P., Myers, A., Parkinson, Simon, Longstaff, A. P., Allen, Gary, Parkinson, S., Fletcher, Simon, Allen, G., Crampton, Andrew, Fletcher, S., Myers, Alan, Crampton, A.   +11 more
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