Results 61 to 70 of about 69,107,912 (284)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Evaluation of measurement technique for a precision aspheric artefact using a nano-measuring machine [PDF]

open access: yes
A precision aspheric artefact is measured in 3D by a commercially available nano-measuring machine (NMM) integrated with a contact inductive sensor as the probe. The mathematics of 3D compensation of the error caused by the probe radius is derived.
Longstaff, Andrew P.   +3 more
core   +3 more sources

Calculation of Tool Offset and Tool Radius Errors Based on On-Machine Measurement and Least Squares Method in Ultra-Precision Diamond Turning

open access: yesPhotonics
Metal mirrors will be widely used in the coming decades. Therefore, as one of the enabling technologies for metal optical freeform surface manufacturing, ultra-precision (UP) diamond turning error compensation has become a research hotspot.
Yao Peng, Han Ding, Dong Zhang, Miao Luo
doaj   +1 more source

Automatic Error Compensation for Free-Form Surfaces by Using On-Machine Measurement Data

open access: yesApplied Sciences, 2019
Currently, most computer numerical control (CNC) controllers lack the function needed to compensate machining errors for free-form surfaces. The objective of this research was to enhance the accuracy and precision of the machined free-form surfaces of a ...
Wei-chen Lee, Yu-tzu Lee, Ching-Chih Wei
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Automated planning to minimise uncertainty of machine tool calibration [PDF]

open access: yes, 2014
When calibrating a machine tool, multiple measurement tasks will be performed, each of which has an associated uncertainty of measurement. International Standards and best-practice guides are available to aid with estimating uncertainty of measurement ...
Longstaff, Andrew P.   +8 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Performance evaluation of a new taut wire system for straightness measurement of machine tools [PDF]

open access: yes, 2014
This paper describes evaluation of a method of measuring the straightness of motion of machine tool axes using a taut wire and an optical sensor head mounted at the tool point location. In contrast to commonly used taut wire instruments, straightedges or
Longstaff, Andrew P.   +4 more
core   +1 more source

On-Machine Measurement and Error Compensation for 6061 Aluminum Alloy Hexagonal Punch Using a Turn-Milling Machine

open access: yesMachines, 2021
For machining parts with complex shapes, consisting of computer numerical control (CNC) machine tools, different CNC machine tools will be used according to the machining method.
Cheng-Hsien Kuo, Po-Cheng Chen
doaj   +1 more source

Home - About - Disclaimer - Privacy