Results 71 to 80 of about 47,819,563 (268)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Precise Orbit Determination for ADEOS-II

open access: yes, 2006
We performed the precise orbit determination of ADEOS-II using single frequency GPS data and reviewed the results. JAXA precise orbit determination system is called “GUTS (Global and high accUracy Trajectory determination system)”.
Yamamoto, Y.   +3 more
core  

Design of optimal Earth pole-sitter transfers using low thrust propulsion [PDF]

open access: yes, 2011
Recent studies have shown the feasibility of an Earth pole-sitter mission using low-thrust propulsion. This mission concept involves a spacecraft following the Earth's polar axis to have a continuous, hemispherical view of one of the Earth's poles.
Biggs, James   +9 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Accuracy Assessment of SGP4 Orbit Information Conversion into Osculating Elements

open access: yes, 2013
The SGP4 model is one of the analytical orbit models applied for the orbit prediction using TLE orbit information. For the orbit accuracy improvement, a model conversion was performed to apply a more precise model. Assuming that a TLE data set is the
Aida, Saika, Kirschner, Michael
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

First In-orbit Experience of TerraSAR-X Flight Dynamics Operations

open access: yes, 2007
TerraSAR-X is an advanced synthetic aperture radar satellite system for scientific and commercial applications that is realized in a public-private partnership between the German Aerospace Center (DLR) and the Astrium GmbH.
Kiehling, Reinhard   +11 more
core  

Rendezvous Simulation for On-Orbit Servicing Missions Using Advanced Robotic Technology

open access: yes, 2013
Increasing complexity and costs of satellite missions promote the idea of extending the operational lifetime or improving functionalities/performance of a satellite in orbit instead of simply replacing it by a new one.
Boge, Toralf, Benninghoff, Heike
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

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