Results 161 to 170 of about 2,769,403 (287)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Distribution and Antimicrobial Resistance Trends of Bloodstream Bacterial Isolates: A 10-year Single-Center Study in China. [PDF]

Infect Drug Resist
He X, Liu M, Wang X, Li S, Zhang Y, Jiang S, Liu Z, Waqas M, Wang X.   +8 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

blaOXA−51-Negative Acinetobacter calcoaceticus–baumannii Complex as a Cause of Human Infection in Peru

Journal of Tropical Medicine
Rosario Oporto-Llerena, Rosario Huerto-Huánuco, Yaneth Quispe-Hualpa, Luciano A. Palomino-Kobayashi, Gabriela Soza, Jesús Rojas-Jaimes, Patricia Gonzales, Luis Pollack, Andrea C. Gomez, Gina Salvador-Luján, Edwin Cuaresma, Nestor Luque, Martín Casapia, Kovy Arteaga-Livias, Yolanda Sáenz, Maria J. Pons, Joaquim Ruiz   +16 more
doaj   +1 more source

Dissecting the population structure, diversity and genetic architecture of rust resistance in wild emmer wheat (Triticum turgidum subsp. dicoccoides). [PDF]

BMC Genomics
Adhikari L, Olivera PD, Raupp J, Sela H, Distelfeld A, Maccaferri M, Bozzoli M, Mazzucotelli E, Brandolini A, Tuberosa R, Özkan H, Wulff BBH, Steffenson BJ, Poland J.   +13 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Author Correction: Semi-automated surveillance of surgical site infections using machine learning and rule-based classification models

npj Digital Medicine
Américo Agostinho, Etienne Chalot, Daniel Teixeira, Davide Bosetti, Niccolò Buetti, Gaud Catho, Stephan Harbarth, Mohamed Abbas   +7 more
doaj   +1 more source

BRAF inhibitor resistance in melanoma: from resistance mechanisms to therapeutic innovations. [PDF]

Mol Biomed
Shang Y, Cao T, Li J, Li J, Zhang L, Ma Q, Feng L, Zhao H.   +7 more
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Trends in antimicrobial resistance and antibiotic use before and during the coronavirus disease 2019 pandemic in a university research and practice hospital in Türkiye. [PDF]

Access Microbiol
Buyukcelik M, Akcam FZ, Uskun E, Sesli Cetin E, Kaya O, Yilmaz GR, Unal O, Nurlu Temel E.   +7 more
europepmc   +1 more source