Results 11 to 20 of about 71,118,458 (209)

Resistance-resistant antibiotics [PDF]

open access: yesTrends in Pharmacological Sciences, 2014
New antibiotics are needed because drug resistance is increasing while the introduction of new antibiotics is decreasing. We discuss here six possible approaches to develop 'resistance-resistant' antibiotics. First, multitarget inhibitors in which a single compound inhibits more than one target may be easier to develop than conventional combination ...
Eric, Oldfield, Xinxin, Feng
openaire   +2 more sources

Resisting Resistance [PDF]

open access: yesAnnual Review of Cancer Biology, 2017
Targeted therapies, immunotherapies, and improved chemotherapies are being developed to reduce the suffering and mortality that come from human cancer. Although these approaches, and in particular combinations of them, are expected to succeed eventually to a large degree, they all suffer one obstacle: Populations of replicating cells move away ...
Ivana Bozic, Martin A. Nowak
openaire   +1 more source

Resistance to “Castration-Resistant” [PDF]

open access: yesThe Oncologist, 2014
The author challenges the use of the phrase “castration resistance,” which is widely used in the literature and also appears in a recent article by Merseburger et al.
openaire   +2 more sources

Antimicrobial resistance surveillance in Europe 2013: Annual Report of the European Antimicrobial Resistance Surveillance Network (EARS-Net) [PDF]

open access: yes, 2014
Portugal - EARS-Net Management Team & National representatives of EARS-Net (Manuela Caniça, José Artur Paiva, Vera Manageiro, Eugénia Ferreira)The results presented in this report are based on antimicrobial resistance data from invasive isolates reported
European Antimicrobial Resistance Surveillance Network (EARS-Net)
core   +1 more source

Resisting Potato Cyst Nematodes With Resistance [PDF]

open access: yesFrontiers in Plant Science, 2021
Potato cyst nematodes (PCN) are economically important pests with a worldwide distribution in all temperate regions where potatoes are grown. Because above ground symptoms are non-specific, and detection of cysts in the soil is determined by the intensity of sampling, infestations are frequently spread before they are recognised.
Ulrike Gartner   +14 more
openaire   +5 more sources

Manual wheelchair's turning resistance: swivelling resistance parameters of front and rear wheels on different surfaces [PDF]

open access: yes, 2019
Purpose: Daily locomotion with a manual wheelchair includes curvilinear movements. However, little is known about the resisting forces in play during turning manoeuvres where the wheels are generally both rolling and swivelling.
BASCOU, Joseph   +3 more
core   +1 more source

ESBL-Producing Escherichia coli Carrying CTX-M Genes Circulating among Livestock, Dogs, and Wild Mammals in Small-Scale Farms of Central Chile

open access: yesAntibiotics, 2021
Antibiotic-resistant bacteria of critical importance for global health such as extended-spectrum beta-lactamases-producing (ESBL)-Escherichia coli have been detected in livestock, dogs, and wildlife worldwide. However, the dynamics of ESBL-E.
Julio A. Benavides   +8 more
doaj   +1 more source

Genome-wide association studies reveal candidate genes associated to bacteraemia caused by ST93-IV CA-MRSA

open access: yesBMC Genomics, 2021
Background The global emergence of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has seen the dominance of specific clones in different regions around the world with the PVL-positive ST93-IV as the predominant CA-MRSA clone ...
Stanley Pang   +5 more
doaj   +1 more source

Transmission of gram-negative antibiotic-resistant bacteria following differing exposure to antibiotic-resistance reservoirs in a rural community: a modelling study for bloodstream infections

open access: yesScientific Reports, 2022
Exposure to community reservoirs of gram-negative antibiotic-resistant bacteria (GN-ARB) genes poses substantial health risks to individuals, complicating potential infections. Transmission networks and population dynamics remain unclear, particularly in
Kasim Allel   +7 more
doaj   +1 more source

A New Dual-Direction SCR With High Holding Voltage and Low Dynamic Resistance for 5 V Application

open access: yesIEEE Journal of the Electron Devices Society, 2019
Dual-directional silicon-controlled rectifiers (DDSCRs), which provide both positive and negative electrostatic discharge (ESD) surge paths, are ESD protection devices with an excellent area efficiency.
Kyoung-Il Do   +2 more
doaj   +1 more source

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